Informatics Publishing Limited

Santosh J. Pawar ¹, Pruthviraj S. Pawar ², Sachin B. Jadhav ², A. S. Alkunte ², S. M. Patil ²

Affiliations
1 C/o-D. K. Mane’s house, Near Mukteshwar-Ashram, Vasant Nagar, Nanded 431602(MS), IN
2 Department of Pharmaceutics, ASPM’s K.T. Patil College of Pharmacy, Osmanabad 413501, IN

Abstract

Nanocapsules have been proposed as drug carrier that may be used as to realize magic bullet in 20^th century, which refers to capable of targating a perticular and releasing its content when desired at site of action Nanocapsules prepared from preformed polymers as active substances carriers is presented. This entails a general review of the different preparation methods nanoprecipitation, emulsion-diffusion, double emulsification, emulsion-coacervation, polymer-coating and layer-by-layer, from the point of view of the methodological and mechanistic aspects involved. Encapsulation of the active substance and the raw materials used. Similarly, a comparative analysis is given of the size, zeta-potential, encapsulation efficiency, active substance Release, stability and in vivo and in vitro pharmacological performances, using as basis the data reported in the different research works published.

Keywords

Nanocapsules, Encapsulation Efficiency, Zeta-Potential, Encapsulation Method.

Full Text