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Kambhoja, S.
- In-vitro Antiprotozoal Activity of Zizyphus jujuba Mill and Lamk
Abstract Views :489 |
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Authors
Affiliations
1 Department of Pharmacognosy, The Oxford College of Pharmacy, Hongasandra, Bangaluru-560068, IN
1 Department of Pharmacognosy, The Oxford College of Pharmacy, Hongasandra, Bangaluru-560068, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 3, No 1 (2011), Pagination: 34-36Abstract
Zizyphus jujuba Mill and Lamk. Is also called as Baer tree, belongs to the family Rhamnaceae. The dried bark was powdered and extracted with various solvents by successive soxhlet hot extraction process with increasing order of polarity. On phytochemical investigation, the different extracts has shown the presence of carbohydrates, alkaloids, steroids, flavonoids and tannins. The different extracts were screened for antiprotozoal activity on Entamoeba histolytica and Giardia lamblia using metronidazole as standard drug. Both acetone and methanol extract showed significant antiprotozoal activity compared to standard drug metronidazole.Keywords
Antiprotozoal Activity, Zizyphus jujuba, Metronidazole, Entamoeba histolytica, Giardia lamblia.
References
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- Evaluation of Antibacterial Activity of the Stem Bark of Alstonia scholaris Linn. R.Br
Abstract Views :231 |
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Authors
Affiliations
1 The Oxford College of Pharmacy, 6/9, Hongasandra, Bangalore-68, Karnataka, IN
2 Department of Pharmacognosy, The Oxford College of Pharmacy, Hongasandra, Bangalore- 560068, Karnataka, IN
1 The Oxford College of Pharmacy, 6/9, Hongasandra, Bangalore-68, Karnataka, IN
2 Department of Pharmacognosy, The Oxford College of Pharmacy, Hongasandra, Bangalore- 560068, Karnataka, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 3, No 4 (2011), Pagination: 180-183Abstract
Alstonia scholaris Linn. R. Br. also called as Devil's tree and Dita bark belongs to the family Apocyanaceae. It is a large, ever green tree, found almost throughout India up to an altitude, 600m. The bark was collected and authenticated by Dr. Madhava Chetty, Sri Venkateshwara University, Tirupathi. The antibacterial activity of the stem bark of Alstonia scholaris Linn. R. Br. was investigated as there is a necessity for the search of new antibiotics as the infectious diseases continue to be the major concern for health institutions, pharmaceutical companies and Governments all over the world, especially with the current increasing trends of multidrug resistance among emerging - reemerging bacterial pathogens to the available modern drug or antibiotics. The plants are the cheapest and safe alternative source of antimicrobials. The powder of the dried stem bark was extracted with different solvents in increasing order of the polarity by soxhelation. Antibacterial activity was tested against both Gram positive (Staphylococcus aureus, Bacillus subtilis) and Gram negative (Pseudomonas aeruginosa, Escherichia coli) organisms using agar disc diffusion method. The methanol and benzene extracts exhibited significant antibacterial activity against Gram negative bacteria and ethanol extract against Gram positive bacteria. Chloroform and acetone extracts exhibited less activity, while petroleum ether and aqueous extracts showed no zone of inhibition. The results were compared with the standard drug, Ampicillin.
Keywords
Alstonia scholaris Linn. R. Br., Antibacterial Studies, Agar Disc Diffusion Method, Ampicillin.- Anthelmintic Activity of the Stem Bark of Juglans regia Linn
Abstract Views :239 |
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Authors
Affiliations
1 The Oxford College of Pharmacy, 6/9, Hongasandra, Bangalore – 68, Karnataka, IN
2 Department of Pharmacognosy, The Oxford College of Pharmacy, Hongasandra, Bangalore- 560068, Karnataka, IN
1 The Oxford College of Pharmacy, 6/9, Hongasandra, Bangalore – 68, Karnataka, IN
2 Department of Pharmacognosy, The Oxford College of Pharmacy, Hongasandra, Bangalore- 560068, Karnataka, IN