Refine your search
Collections
Co-Authors
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Athlekar, S. V.
- Synthesis and Biological Activity of 5-Substituted and 5, 6-Disubstituted-2-(N, N-Dialkyl Thiocarbamido) Benzimidazoles
Abstract Views :183 |
PDF Views:0
Authors
Affiliations
1 Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai-12, IN
1 Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai-12, IN
Source
Asian Journal of Research in Chemistry, Vol 3, No 2 (2010), Pagination: 305-307Abstract
Heterocyclic compounds such as 5-substituted and 5,6-disubstituted-2-(N, N-dialkyl Thiocarbamido) benzimidazoles were synthesized by condensation of 5-substituted and 5,6-disubstituted-2-mercapto benzimidazoles with N, N-dialkyl carbamoyl chlorides and triethyl amine in dry 1,4-dioxane. Synthesized compounds were further screened for their biological activity and found to have good to moderate antibacterial and antifungal activity. The structures of compounds have been established on basis of their elemental analysis and spectral data (IR and NMR).Keywords
Mercapto Benzimidazole, Antifungal, Antibacterial, N, N-Dialkyl Carbamoyl Chloride.- Synthesis and Antimicrobial Activity of 5-Substituted-2-(1-H-Benzimidazole) Sulfonamides
Abstract Views :183 |
PDF Views:0
Authors
Affiliations
1 Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai-12, IN
1 Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai-12, IN
Source
Asian Journal of Research in Chemistry, Vol 3, No 2 (2010), Pagination: 335-338Abstract
Heterocyclic compounds such as 5-substituted-2-(1-H-benzimidazole) sulfonamides were synthesized by condensation of 5-substituted-2-(1-H-benzimidazole)-sulfonyl chloride and 2-aminoheterocycles with triethyl amine in dry acetone. The synthesized compounds were checked for their antimicrobial potency by screening them against two bacterial strains as well as one fungal strain. The structures of compounds have been established on the basis of their elemental analysis and spectral data.Keywords
Sulphonamides, 2-Mercapto Benzimidazole, Antifungal, Antibacterial.- Synthesis and Antimicrobial Evaluation of Benzimidazole Analogs
Abstract Views :202 |
PDF Views:0
Authors
Affiliations
1 Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai-12, IN
1 Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai-12, IN
Source
Asian Journal of Research in Chemistry, Vol 3, No 2 (2010), Pagination: 342-345Abstract
A series of benzimidazole phenylthiocarbamoyl derivatives were synthesized by condensing substituted 2-mercaptobenzimidazole with substituted benzoyl chlorides. These benzimidazole derivatives were evaluated for their antibacterial activity against Gram Positive bacteria Staphylococcus aureus (ATCC 3750) and Gram Negative bacteria Salmonella typhi (NCTC 786), as well as antifungal activity against a fungal strain Candida albicans (ATCC 10231). It was observed that the 5-naphthoxy-6-chloro benzimidazole derivatives having dichloro substitutions on the phenylthiocarbamoyl part of the molecule showed better activity than the rest.Keywords
Benzimidazole, Antimicrobial, Phenylthiocarbamoyl Derivatives, Benzoyl Chloride.- Synthesis and Biological Evaluation of New Benzothiazole Derivatives
Abstract Views :180 |
PDF Views:0
Authors
Vrushali N. Patil
1,
Ameya Yadav
1,
A. S. Bobade
1,
S. V. Athlekar
1,
L. S. Patil
1,
Abhay Chowdhary
1
Affiliations
1 Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai-400012, IN
1 Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai-400012, IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 4 (2009), Pagination: 513-515Abstract
A series of 2-N-acetyl-[2’-(thieno substituted aryl ketone)-5’-methyl-1’,3’,4’-oxadiazolyl] benzothiazole (5a-e) have been synthesized. These structures are determined by the elemental analysis and spectral data (IR, 1H-NMR). These new derivatives are evaluated for in vitro antimicrobial activity against Staphylococcus aureus ATCC 3750, Salmonella typhi NCTC 786, Candida albicans ATCC 10231 and Aspergillus niger ATCC 16404.Keywords
2-Amino Benzothiazole, 1,3,4-Oxadiazole, Anti-Bacterial, Anti-Fungal.- Synthesis and Antimicrobial Activity of Some Benzimidazolyl Pyrazolone Derivatives
Abstract Views :205 |
PDF Views:0
Authors
Ameya G. Yadav
1,
Vrushali Patil
1,
A. S. Bobade
1,
S. V. Athlekar
1,
L. S. Patil
1,
Abhay Chowdhary
1
Affiliations
1 Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai-400012, IN
1 Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai-400012, IN