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Saini, Rakesh
- Synthesis and Analgesic Activity of 2, 5 Di-Substituted 1, 3, 4 Oxadiazoles
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Authors
Affiliations
1 Dept. of Pharmacy, Pranveer Singh Institute of Technology, Kalpi Road, Bhauti, Kanpur-08020, (U. P.), IN
2 Department of Pharmacy, Aligarh College of Pharmacy, Aligarh (U.P), IN
3 Department of Pharmacy, Allahabad Agriculture Deemed University, Allahabad (U.P), IN
1 Dept. of Pharmacy, Pranveer Singh Institute of Technology, Kalpi Road, Bhauti, Kanpur-08020, (U. P.), IN
2 Department of Pharmacy, Aligarh College of Pharmacy, Aligarh (U.P), IN
3 Department of Pharmacy, Allahabad Agriculture Deemed University, Allahabad (U.P), IN
Source
Asian Journal of Research in Chemistry, Vol 3, No 2 (2010), Pagination: 292-295Abstract
1, 2, 3 benzotriazole derivative also show several pharmacological activities viz.example. Antimicrobial activity, Anti inflammatory, Anti analgesic activity, Anticancer etc. On the basis of our observation the parent research work was carried out to synthesize 1, 2, 3 triazole substituted 1, 3, 4 oxadiazoles and to further evaluate Analgesic activity. Synthesis of (ethyl 2- (1H Benzo [d] [1, 2, 3] triazole-1-yl] acetate) and (2H-benzo [d] [1,2,3] triazole-1-yl aceto hydrazine) along with their derivatives has been done. The entire synthesized compounds were characterized by UV, IR and 1H-NMR specteoscopy. The Antimicrobial activity of the synthesized compounds was evaluated, on albino rats. The present investigation deals with the synthesized compounds possessing good Analgesic activity.Keywords
Hydrazine, Benztriazole, Analgesic Activity.- Chemical Investigation of Polygonatum verticillatum
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Authors
Affiliations
1 Pranveer Singh Institute of Technology, Bhauti, Kanpur (U.P), IN
2 Jamiya Hamdard University, New Delhi, IN
3 Govt. P.G. College, Hamirpur (U.P), IN
1 Pranveer Singh Institute of Technology, Bhauti, Kanpur (U.P), IN
2 Jamiya Hamdard University, New Delhi, IN
3 Govt. P.G. College, Hamirpur (U.P), IN
Source
Asian Journal of Research in Chemistry, Vol 3, No 1 (2010), Pagination: 20-21Abstract
Polygonatum verticillatum, Convallariaceae erect glabrous herb upto 20 cm. in height with thick ischolar_main stock. Upper part of the stem the leafy zig-zag grooved, leaves whorled sensible linear or lanceolate flowers 2-3 together, white, pinkish and white or pale green in whorled racemes fruits berries, red when ripe. Root stock is sweet, cooling, Emollient, Diuretic aphrodisiac, galactogogue, appetizing, tonic. It is useful in vitiated condition of pitas and vat, burning sensation fever, stongury, seminal weakness, anorexia and general debility. The author have done some work and isolated few higher fatty acids from the rhizome of this plant.- Synthesis and Evaluation of Pyrrole Derivative Conjugates of Aspirin as Anti-Platelet Agents
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Authors
Saurabh Chaturvedi
1,
Rakesh Saini
1,
A. N. Kesari
1,
Awani Rai
1,
Neelotma Maurya
1,
M. Shahar Yar
2
Affiliations
1 Pranveer Singh Institute of Technology, Bhauti, Kanpur-208020, (U.P), IN
2 Jamiya Hamdard University, New Delhi, IN
1 Pranveer Singh Institute of Technology, Bhauti, Kanpur-208020, (U.P), IN
2 Jamiya Hamdard University, New Delhi, IN
Source
Asian Journal of Research in Chemistry, Vol 3, No 1 (2010), Pagination: 22-25Abstract
A new series of NSAID’S in which aspirin is joined by ester linkage to pyrrole-2-carboxylic acid were synthesized and tested for anti-platelet activity. Related propyl esters of aspirin and aspirin as such were taken as references. All the compounds described here show anti-platelet activity but they do not behave as prodrugs of aspirin in blood serum.Keywords
NSAID’S, Aspirin, Anti-Platelet Agents, Pyrrole.- Synthesis and Biological Evaluation of 2, 5 Di-Substituted 1, 3, 4 Oxadiazoles
Abstract Views :174 |
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Authors
Affiliations
1 Department of Pharmacy, Pranveer Singh Institute of Technology, Kalpi Road, Bhauti, Kanpur-208020, Uttar Pradesh, IN
2 Department of Pharmacy, Jamia Hamdurd, New Delhi, IN
1 Department of Pharmacy, Pranveer Singh Institute of Technology, Kalpi Road, Bhauti, Kanpur-208020, Uttar Pradesh, IN
2 Department of Pharmacy, Jamia Hamdurd, New Delhi, IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 1 (2009), Pagination: 34-36Abstract
Synthesis of (ethyl 2-(1H Benzo [d] [1, 2, 3] triazole-1-yl] acetate) and (2H-benzo [d] [1, 2, 3] triazole -1-yl aceto hydrazine) along with their derivatives has been done. The entire synthesized compounds were characterized by UV, IR and 1H-NMR spectroscopy. The Antimicrobial activity of the synthesized compounds was evaluated, on Streptococcus aureus and Esteria coli. The present investigation deals with the synthesized compounds possessing good antimicrobial activity.Keywords
Esterification, Benztriazole, Antimicrobial Activity.- Ester and Fatty Acid from Pleurospermum densiflorum
Abstract Views :159 |
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Authors
Affiliations
1 Department of Pharmacy, Pranveer Singh Institute of Technology, Kalpi Road, Bhauti, Kanpur-208020, Uttar Pradesh, IN
2 Department of Chemistry, Govt. PG College, Hamirpur-210301 (U.P), IN
1 Department of Pharmacy, Pranveer Singh Institute of Technology, Kalpi Road, Bhauti, Kanpur-208020, Uttar Pradesh, IN
2 Department of Chemistry, Govt. PG College, Hamirpur-210301 (U.P), IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 1 (2009), Pagination: 41-42Abstract
High altitude herbs were used as herbal perfume and used incense in the folk of Himalayan region. From aerial part of the plants the alcohols and higher ester of fatty acids were isolated and identified. It is used in the manufacture of metallic stearates, pharmaceuticals, soaps, cosmetics, and food packaging. It is also used as a softener, fragrance.Keywords
Pleurospermum densiflorum, Ester and Fatty Acid.- Preliminary Results of Hybrid Bathymetry and GLOF Risk Assessment for Neelkanth Lake, Lahaul Himalaya, India
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Authors
Affiliations
1 Department of Geography, Government College, Dujana, Jhajjar 124 102, IN
2 Centre for the Study of Regional Development, Jawaharlal Nehru University, New Delhi 110 067, IN
3 Department of Geography, Dr Hari Singh Gour Central University, Sagar 470 003, IN
4 Department of Geography, Government College, Dujana,Jhajjar 124 102, IN
1 Department of Geography, Government College, Dujana, Jhajjar 124 102, IN
2 Centre for the Study of Regional Development, Jawaharlal Nehru University, New Delhi 110 067, IN
3 Department of Geography, Dr Hari Singh Gour Central University, Sagar 470 003, IN
4 Department of Geography, Government College, Dujana,Jhajjar 124 102, IN