Informatics Publishing Limited

J. Anbu , R. Vasuki , P. Shanmugasundaram , Shiny George , R. Sujatha , M. Vijey Aanandhi

Abstract

The methanolic extract of the Citrus sinensis peel was screened for antidiarrhoeal activity using animal models against castor oil induced diarrhoea. The parameters evaluated are small intestine secretion by enteropooling assay, rate of defecation and small intestine transit. The methanolic extract showed significant activity (p<0.05) against castor oil induced diarrhoea and interluminal accumulation of fluid. It also reduced gastrointestinal motility after charcoal meal administration in albino mice. The results indicates that the action of Citrus sinensis peel extract (CSPE) could be through a combination of inhibition of elevated prostaglandin biosynthesis and reduced propulsive movement of the small intestine.

Keywords

Citrus Sinensis, Anti Diarrhoeal, Albino Mice, Castor Oil and Charcoal Meal

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A. Suneetha ¹, Pandit M. Risheela ¹, R. Sujatha ¹

Affiliations
1 Department of Pharmaceutical Analysis, Hindu College of Pharmacy, Amaravathi Road, Guntur- 522 002, Andhra Pradesh, IN

Abstract

The present method describes the development of a validated RP-HPLC for determination of ormeloxifene hydrochloride in presence of its degradation products or other pharmaceutical excipients. The drug substance was subjected to stress conditions of acid (2N HCl), alkali (2N NaOH), oxidative (30%H₂O₂), neutral, thermal and photolytic studies. Seperation was carried out on Agilent XDB C18 column,(250×4.6mm I.D, Particle size 5μm) by using mobile phase consisting of a mixture of buffer: acetonitrile: methanol (20:35:45,v/v/v) with the flow rate of 1.0mL/min. UV detection was performed at 245nm and retention time was found to be 5.48min. The method was validated for linearity, accuracy and precision. Linearity for ormeloxifene was in the range of 30-90μg/mL with correlation coefficient values 0.9999. The mean recoveries were found in the range of 99.73-100.84% and the %RSD was found to be less than 2% indicated, that the method is more accurate and precise. The Limit of Detection and Limit of Quantification were 0.11μg/ml and 0.32ì g/ml respectively, which indicate sensitivity of the method. No interfering peaks were found in the chromatogram indicating that excipients used in tablet formulations did not interfere with the estimation of the drug by proposed HPLC method.

Keywords

Ormeloxifene, RP-HPLC.

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G. Kuppuswami ¹, R. Sujatha ², W. B. Vasantha Kandasamy ³

Affiliations
1 Department of Mathematics, Jeppiaar Engineering College, Chennai - 600119, Tamil Nadu, IN
2 Department of Mathematics, SSN College of Engineering, Chennai - 603 110, Tamil Nadu, IN
3 Department of Mathematics, IIT, Madras, Chennai - 600036, Tamil Nadu, IN

Abstract

This paper presents a method to analyze the traffic flow pattern in Velachery Vijaya Nagar Signal, Chennai. Study of traffic congestion is significant these days so that traffic regulation can be made accordingly to avoid congestion and waiting time. The peak time and non-peak time are identified using the row sum of the Combined Effective Time Dependent Data (CETD) matrix in this duration.

Keywords

ATD Matrix, CETD Matrix, RTD Matrix, Traffic Flow.

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Usha Chandrasekhar ¹, A. Sakthivelmani ¹, R. Sujatha ²

Affiliations
1 Sri Avinashilingam Home Science College for Women, Coimbatore-43, IN
2 Sri Avinashilingam Home Science College for Women, Coimbatore-43, HU

Abstract

Health and sports are closely linked and physical exercise is as important to the mind as it is to the body. Nutrition and well being hence assumes vital role in the field of sports. During the past 20 years there have been great developments in the scientific understanding of the role of nutrition in health and physical performance. Efforts have constantly been made by the scientists to find out a suitable diet which can increase the physical performance or capacity of the athletes.

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S. Gopalakrishnan ¹, R. Sujatha ¹

Affiliations
1 Department of Pharmaceutical Chemistry, Manonmaniam Sundaranar University, Tirunelveli-627 012, Tamilnadu, IN

Abstract

Cardanol, a major ingredient of Cashew Nut Shell Liquid (>87%) is a long chain meta-substituted phenol. It reacts with furfural in different mole ratios in the presence of dicarboxylic acid as catalyst to give novolac resin. The characterized cardanol-furfural resin can be properly modified to a high molecular weight hydroxyalkylated derivative, a nucleophilic compound (polyol) through epoxidation followed by hydrolysis.Polyurethanes were formulated by reaction of the hydroxylalkylated cardanol-furfural resin with the commercially available polyol, polypropylene glycol-1200(PPG-1200) and 4, 4'- Diphenylmethane diisocyanate/Toluene diisocyanate. These polyurethanes were characterized with respect to their resistance to chemical reagents and mechanical properties such as tensile strength, percentage of elongation and hardness. Thermal properties were characterized by Thermo gravimetric Analysis (TGA).

Keywords

Cardanol, Polyurethane, Tensile Strength, Thermal Properties.

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R. Sujatha ¹, M. Durgadevi ¹, K. Janani ¹, A. Soundarya ¹, S. Thilagavathi ¹

Affiliations
1 Department of Information Technology, M. Kumarasamy College of Engineering, Karur, Tamil Nadu, IN

Abstract

Present days, individuals over the universe are getting progressively delicate to their eating routine. Unequal eating routine can cause numerous issues like weight gain, heftiness, sugar, and so forth. So various frameworks were grown to break down food pictures to compute calorie, sustenance level and so on. Food is one of the most significant necessities of each living being on earth. The individuals require their food to be new, unadulterated and of standard quality. The measures forced and computerization completed in food preparing industry deals with food quality. Presently a day, individuals over the universe are getting progressively delicate to their eating regimen. Weight is the significant reason for overweight this prompts the sort II diabetes, coronary illness and malignant growth. Estimating the food is significant for a fruitful solid eating regimen. Estimating calorie and sustenance in everyday food is one of the test techniques. Cell phone assumes a crucial job in the present innovative world utilizing this strategy will upgrade the issue in the admission of dietary utilization. In this venture, a food picture acknowledgement framework for estimating the calorie and sustenance esteem was created. The client needs to snap the photo of the food picture this framework will arrange the picture to recognize the kind of food and segment size and the acknowledgement data will gauge the quantity of calories in the food. In this framework the food region, size and volume will be utilized to figure the calorie and nourishment in an exact manner.

Keywords

BoW, CNN, DenseNet, MSMVFA, ResNet, VGG.

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