Informatics Publishing Limited

N. N. Magadalenal ¹, R. Prabhu ¹, R. M Inbaraj ¹

Affiliations
1 Department of Zoology, Madras Christian College, Tambaram, Chennai, 600 059, IN

Abstract

No Abstract

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N. Kannaiya Raja ¹, K. Arulanandam ², R. Prabhu ³

Affiliations
1 CSE Department, Arulmigu Meenakshi Amman College of Engineering, Thiruvannamalai district, Near Kanchipuram, IN
2 CSE Department, Ganadipathy Tulsi’s Jain Engineering College, Vellore, IN
3 Arulmigu Meenakshi Amman College of Engineering, Thiruvannamalai District, Near Kanchipuram, IN

Abstract

Multi-pattern string matching remains a major performance bottleneck in network intrusion detection and anti-virus systems for high-speed deep packet inspection (DPI). Although Aho-Corasick deterministic finite automaton (AC- DFA) based solutions produce deterministic throughput and are widely used in today's DPI systems such as Snort and ClamAV, the high memory requirement of AC-DFA (due to the large number of state transitions in AC-DFA) inhibits efficient hardware implementation to achieve high performance.. Novel and scalable pipeline architecture for memory- efficient multi-pattern string matching is then presented. The architecture can be easily extended to support multi-character input per clock cycle by mapping a compressed AC-DFA onto multiple pipelines. In this paper the architecture to support enhanced multi-character input per clock cycle to achieve multiplicative throughput improvement. By using multi pipelining Now we can use the efficient architecture also available to support much larger pattern sets by using a limited number of external memory and also work done integrating proposed string matching architecture with DPI processing engine such packet header and other flags with regular expressing. Very fast regular expression matching is currently used here for applications searching for large pattern sets with increasingly faster data streams and minimize the through put by pipelining process and comparing him high level to reduce the state and minimize the throughput.

Keywords

Deep Packet Inspection, DFA, FPGA, Pipeline, String Matching.

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G. Shanthi ¹, V. Sivakumari ², S. Giridaran ³, R. Prabhu ³

Affiliations
1 Department of Botany, Kunthavai Nacchiyar Government Arts College for Women, Thanjavur (T.N.), IN
2 Department of Environmental and Herbal Sciences, Tamil University, Thanjavur (T.N.), IN
3 Department of Biochemistry, Bharathidasan University, Trichy (T.N.), IN

Abstract

Coactivation of platelets and the blood coagulation cascade contributes to the pathophysiology of antithrombotic effect. Combination of antiplatelet drugs may be needed for maximizing the prevention and treatment of thrombosis. Aspirin inhibits platelets by inhibiting cyclooxygenase and was shown to reduce platelet-dependent thrombin generation, whereas clopidogrel inhibits platelet activity by blocking the platelet ADP receptors. The present study demonstrates that clopidogrel was an effective antithrombotic agent. Further the combination of aspirin and clopidogrel increases antithrombotic effect without increasing bleeding time.

Keywords

Coronary Artery Disease or Atherosclerosis and Transient Ischemic Attack.

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G. Shanthi ¹, V. Sivakumari ², R. Prabhu ³, S. Giridaran ³

Affiliations
1 Department of Botany, Kunthavai Nacchiyar Government Arts College for Women, Thanjavur (T.N.), IN
2 Department of Environmental and Herbal Sciences, Tamil University, Thanjavur (T.N.), IN
3 Department of Biochemistry, Bharathidasan University, Trichy (T.N.), IN

Abstract

Rheumatoid arthritis is potentially crippling disease. Numerous pharmacologic agents are available for treatment of rheumatoid arthritis; the goal in therapy is relief of pain and inflammation, through modification of disease process. Several corticosteroids play an important role in the management of RA, among corticosteroids methylprednisolone shows beneficial effect. In this study the level of ADA activity, C-reactive protein and erythrocyte sedimentation rates are reduced after treatment with methylprednisolone compared to rheumatoid arthritis patients. This shows that methylprednisolone involves in several metabolism of inflammatory process. But it does not shown any significant changes in pain score compared to rheumatoid arthritis patients, this may be due to it does not involves in analgesic process. In rheumatoid arthritis pain and inflammation are important two symptoms. Based on present study it can be concluded that methylprednisolone has more anti-inflammatory effect compared to analgesic effect. So, while treating rheumatoid patient with methylprednisolone they should take care of pain of patient with some other pain killers like NSAIDS or potent opioids. The understanding of the pathophysiology of rheumatoid arthritis and precise knowledge of the possible triggers of the inflammation may open novel therapeutic approaches. Hence, the present study suggests the importance of measuring the biomarkers of inflammation assessed in the study not only to determine the severity of inflammation and the effect of treatment with drug.

Keywords

Rheumatoid Arthritis, ADA Activity, C-Reactive Protein and Erythrocyte.

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