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Mukherjee, Pulok K.
- Therapeutic Potentials of Andrographolide from Andrographis paniculata : a Review
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Journal of Natural Remedies, Vol 6, No 1 (2006), Pagination: 1-13Abstract
Andrographolide, a bitter principle obtained from Andrographis paniculata (Family: Acanthaceae), is a diterpene lactone, responsible for various pharmacological activities. This is a well-known phytoconstituent from Indian System of Medicine, used in the management of different diseases since time immemorial. Research activities worldwide to exhibit the beneficial role of Andrographolide are continuously enriching the therapeutic arsenal of this important phytomolecule. In addition to the well known pharmacological activities like hepatoprotective, antioxidant, hypoglycemic etc., recent advances in the management of immune system and neoplastic diseases make andrographolide the phytomolecule of the hour. In this report an effort has been given to highlight the research findings related to therapeutic potentials and recent development in the pharmacological activities of andrographolide.Keywords
Andrographolide, Andrographis paniculata, Therapeutic Activity, PhytoconstituentsFull Text
- Phytochemical and Therapeutic Profile of Aloe vera
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PDF Views:295
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Journal of Natural Remedies, Vol 14, No 1 (2014), Pagination: 1 - 26Abstract
Aloe vera (L.) Burm. f. (Family Liliaceae) is an evergreen perennial succulent plant widely used from antiquity. Aloe vera contains various carbohydrate polymers, notably glucomannans, along with a range of other organic and inorganic components. Phenolic compounds have been identified so far as chromone, anthraquinone or anthrone derivatives. Three distinct preparations of aloe plants are mostly used in medicinal practices that are quite different in their chemical composition and their therapeutic properties, aloe latex (aloe); aloe gel (Aloe vera); and, aloe whole leaf (aloe extract). Aloe latex is used for its laxative effect; aloe gel is used topically for skin ailments, such as wound healing, psoriasis, genital herpes and internally by oral administration in diabetic and hyperlipidaemic patients and to heal gastric ulcers; and, aloe extract is potentially useful for cancer and AIDS. Aloe vera possesses several pharmacological properties such as promoting and healing wound and burn, frost-bite healing, with addition to having antiinflammatory, antifungal, hypoglycemic and gastroprotective properties. This review explored the phytochemical and pharmacological knowledge as well as several promising aspects for research on aloe.Keywords
Aloe vera, Aloe, Indian Aloe, Kumari, Ghritakumari, Aloin.Full Text
- Metabolomics of Medicinal Plants - A Versatile Tool for Standardization of Herbal Products and Quality Evaluation of Ayurvedic Formulations
Abstract Views :314 |
PDF Views:79
Authors
Pulok K. Mukherjee
1,
Ranjit K. Harwansh
1,
Shiv Bahadur
1,
Sayan Biswas
1,
Lalitha N. Kuchibhatla
2,
Sarada D. Tetali
2,
A. S. Raghavendra
2
Affiliations
1 School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700 032, IN
2 School of Life Sciences, Department of Plant Sciences, University of Hyderabad, Hyderabad 500 046, IN
1 School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700 032, IN
2 School of Life Sciences, Department of Plant Sciences, University of Hyderabad, Hyderabad 500 046, IN
Source
Current Science, Vol 111, No 10 (2016), Pagination: 1624-1630Abstract
Secondary metabolites from plants provide lead molecules for drug development. Metabolomics is a modern omic-technique for comprehensive analysis of phytochemicals. Advances in mass spectrometry (MS) based platforms like GC-MS and LC-MS, helped in separation and identification of several metabolites. Such analysis can be a valuable tool for identifying potential biomolecules from medicinal plants. Despite the potential use, metabolomics data of Indian medicinal plants and spices are extremely limited. Similarly, metabolomic studies on Ayurvedic formulations, e.g. Triphala/Trikatu, are lacking. Our review emphasizes the importance of metabolomics of Indian medicinal plants, crucial for quality evaluation and scientific validation of herbal products.Keywords
Metabolomics, Medicinal Plants, Metabolite Profiling, New Molecules, Quality Evaluation.Full Text
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