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Gaikwad, Puja S.
- Bioanalytical Method Validation
Abstract Views :203 |
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1 College of Pharmacy (D.Pharm) Degaon, Satara, (MH) - 415 004, IN
1 College of Pharmacy (D.Pharm) Degaon, Satara, (MH) - 415 004, IN
Source
Asian Journal of Pharmaceutical Analysis, Vol 5, No 4 (2015), Pagination: 219-225Abstract
The Bioanalytical method validation includes all of the procedures that demonstrate a particular method used for a quantitative measurement of analytes in a given biological matrix is selective, sensitive, reliable and reproducible for the deliberate use. Measurement of drug concentrations in biological matrices is an important aspect of medicinal product development for those products containing new active substances and generic products. Such data may be required to support new applications as well as variations to licensed drug products. The results of toxic kinetic, pharmacokinetic and bioequivalence studies are used to make critical decisions supporting the safety and efficacy of a medicinal drug substance or product. It is therefore paramount that the applied Bioanalytical methods used are well characterized, fully validated and documented to a satisfactory standard in order to yield reliable results.Keywords
BMV-Bioanalytical Method Validation.- A Compressive Review on the Study of Nanotechnology for Herbal Drugs
Abstract Views :328 |
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1 College of Pharmacy (D.Pharm), Degaon, Satara, (MH) - 415 004, IN
1 College of Pharmacy (D.Pharm), Degaon, Satara, (MH) - 415 004, IN
Source
Asian Journal of Pharmaceutical Research, Vol 5, No 4 (2015), Pagination: 203-207Abstract
The traditional medicine system is gaining wider popularity in the present times leading to increase in its commercialization at an international level. Ayurveda can serve as an excellent template for the development of nanomedicine for human theragnostics. Nanoparticals are colloidal systems with particles verying in size from 10 nm to 100 nm. The nano formulations are reportated to have remarkable advantages over respective crude drugs preparations and conventional formulations of plant actives or extracts which includes enhancement of solubility, bioavaibility, protection from toxicity, enhancement of pharmacological activity, reduction in dose enhancement of stability, improved tissue macrophages distribution, sustained delivery and protection from physical and chemical degradation. The present study shows that traditional medicines may hold strong relevance in the emerging era of nanomedicine. Thus nano sized novel drug delivery system of herbal drugs has a potential future for enhancing the activity and overcoming problem associative with herbals.Keywords
Herbal Drugs, Nanomedicine, Novel Drug Delivery System.- A Comprehensive Review on Biodegradable Polymers
Abstract Views :332 |
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1 College of Pharmacy (D. Pharm), Degaon, Satara (MH) 415 004, IN
1 College of Pharmacy (D. Pharm), Degaon, Satara (MH) 415 004, IN
Source
Asian Journal of Research in Pharmaceutical Sciences, Vol 6, No 2 (2016), Pagination: 65-76Abstract
Biodegradable polymers have been widely used in biomedical applications because of their known biocompatibility and biodegradability. Degradable polymeric biomaterials are preferred candidates for developing therapeutic devices such as temporary prostheses, three dimensional porous structures as scaffolds for tissue engineering and as controlled/sustained release drug delivery vehicles. Biodegradable materials are used in packaging, agriculture, medicine and other areas. In the biomedical area, polymers are generally used as implants and are expected to perform long term service. These improvements contribute to make medical treatment more efficient and to minimize side effects and other types of inconveniences for patients. The following review presents an overview of the different biodegradable polymers and their applications.Keywords
Biodegradable, Biocompatibility, Polymers.- Pleiotropic Effects of Statins
Abstract Views :176 |
PDF Views:2
Authors
Affiliations
1 College of Pharmacy (D.Pharm) Degaon, Satara, (MH)- 415 004, IN
2 College of Pharmacy (D.Pharm) Degaon, Satara, (MH) - 415 004, IN
1 College of Pharmacy (D.Pharm) Degaon, Satara, (MH)- 415 004, IN
2 College of Pharmacy (D.Pharm) Degaon, Satara, (MH) - 415 004, IN
Source
Asian Journal of Research in Pharmaceutical Sciences, Vol 5, No 1 (2015), Pagination: 55-58Abstract
Statins are the most commonly prescribed drugs worldwide, are cholesterol lowering agents used to manage and prevent cardiovascular and coronary heart diseases. Recently a multifaceted actions in different physiological and pathological conditions has been also proposed for statins such as antiiflammation, neuroprotection etc. Statins have been shown to act through cholesterol dependant & independent mechanisms which are able to affect several tissue functions and modulate specific signal transduction pathways. Here we review the pharmacology of statins, providing a comprehensive update of the current knowledge of their effects on tissues, biological processes & pathological conditions; but statins are now becoming recognized as powerful anti-inflammatory agents that exert beneficial effects beyond low density lipoprotein cholesterol reduction.- Quality by Design
Abstract Views :175 |
PDF Views:2
Authors
Affiliations
1 College of Pharmacy (D. Pharm), Degaon, Satara (MH)-415 004, IN
1 College of Pharmacy (D. Pharm), Degaon, Satara (MH)-415 004, IN
Source
Asian Journal of Research in Pharmaceutical Sciences, Vol 6, No 1 (2016), Pagination: 45-50Abstract
Quality by design (QbD) is an essential part of the modern advance to pharmaceutical quality. QbD is best key to build a quality in all pharmaceutical products. Under this concepts of Be throughout design and growth of product, it is important to identify desire product performance report [Target product profile (TPP), Quality Target product profile (QTPP)] and identify critical quality attributes (CQA). To recognize the impact of raw material [critical material attributes (CAM)], critical process parameters (CPP) on the CQAs and identification and control sources of changeability. The plan of pharmaceutical development is to design a quality products and its manufacturing process always deliver the future performance of the product. The base of Quality by design is ICH Guidelines Q8 for Pharmaceutical for development, Q9 quality risk management, Q10 for pharmaceutical quality systems.Keywords
QBD-Quality by Design.- Role of Dental and Healthcare Professionals in Preventing Oral Cancer
Abstract Views :173 |
PDF Views:2
Authors
Affiliations
1 College of Pharmacy (D.Pharm), Degaon, Satara (MH) - 415 004, IN
1 College of Pharmacy (D.Pharm), Degaon, Satara (MH) - 415 004, IN
Source
Asian Journal of Research in Pharmaceutical Sciences, Vol 5, No 4 (2015), Pagination: 239-246Abstract
Oral cavity cancer, or just oral cancer, is cancer that start in the mouth (also called the oral cavity). Oropharyngeal cancer starts in the oropharynx, which is the part of the throat just behind the mouth. The major causes of oral cancer include tobacco use, areca nut chewing and heavy alcohol drinking; avoiding these can prevent the disease. Preceded by precancerous lesions, early oral cancers present as small painless ulcers or growths that can be detected, by careful physical examination, and if effectively treated by the physician. Prevention, early detection and treatment are effective interventions to reduce the worldwide burden of oral cancer. Early detection of oral cancer needs more than just understanding of the signs and symptoms of disease. The process must be managed effectively and handled sensitively. Every member of the dental team has a part to play and protocols should be developed for effective delivery of Dental and healthcare professionals have a crucial role to play in raising awareness of the dangers to oral health associated with smoking and the use of smokeless tobacco. Early detection of oral cancer needs more than just understanding of the signs and symptoms of disease. In its early stages, oral cancer can be treated in up to 90% of cases.Keywords
Oral Cancer, Early Detection, Prevention, Treatment.- DNA Vaccines: A Hope Full Ray in Immunology
Abstract Views :220 |
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Authors
Affiliations
1 College of Pharmacy (D. Pharm), Degaon, Satara, IN
1 College of Pharmacy (D. Pharm), Degaon, Satara, IN