Informatics Publishing Limited

Ruchi Dabas ¹, Mahesh Kumar ², Sat Pal ³, Virender Verma ⁴, Suman Sharma ⁵, Praveen Prashant ⁶

Affiliations
1 Department of Ophthalmology, PGIMS, Rohtak, IN
2 HCMS, IN
3 Department of Physiology, PGIMS, Rohtak, IN
4 Dept of Pediatrics, PGIMS, Rohtak, IN
5 Dept. Medicine, PGIMER, Dr RML Hospital, New Delhi, IN
6 Dept. of Physiology, PGIMS, Rohtak, IN

Abstract

Retinoblastoma is the most common intraocular malignancy in children with a reported incidence averaging about 1 in 15000 to 1 in 18000 livebirths . Like other solid tumors of childhood ,this tumor also results from a genetic disturbance .Early diagnosis and awareness about this tumor is important for saving the eye and life of the affected child. Pediatrician may be the first contact of the parents of these children. Awareness among pediatricians is a must for avoiding delay in referral to ocular oncologists.

Keywords

Retinoblastoma, Childern.

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Ruchi Dabas ¹, Mahesh Kumar ², Sat Pal ³, Virender Verma ⁴, Suman Sharma ⁵, Praveen Prashant ⁶

Affiliations
1 Dept. of Ophthalmology, PGIMS, Rohtak, IN
2 HCMS, IN
3 Department of Physiology, PGIMS, Rohtak, IN
4 Dept of Pediatrics, PGIMS, Rohtak, IN
5 Dept. Medicine, PGIMER, Dr RML Hospital, New Delhi, IN
6 Dept. of Physiology, PGIMS, Rohtak, IN

Abstract

Endophthalmitis remains a catastrophic complication of intraocular surgery and penetrating ocular trauma despite recent advances in diagnosis and therapy. The incidence has decreased nowadays due to an improved knowledge, better availability of diagnostic facilities and management options.

Keywords

Endophthalmitis, Management.

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Sumanand Sonia ¹, Pragya ², Nupur ³, Praveen Prashant ⁴, Sat Pal ⁴

Affiliations
1 Department of Skin and V D, BPS GMCW. KhanpurKalan, Sonepat, IN
2 Department of Community Medicine, Pt BD Sharma PGIMS, Rohtak, Haryana, IN
3 Department of Radiotherapy, Pt BD Sharma PGIMS, Rohtak, Haryana, IN
4 Department of Physiology, Pt BD Sharma PGIMS, Rohtak, Haryana, IN

Abstract

Celiac disease came to notice during world war II when due to wheat and other cereals shortage alternate diet was accepted and it improved symptoms in patients with celiac disease. Worldwide prevalence in white population is around 1%.With newer diagnostic techniques and high penetration of health facilities it's diagnostic reporting is increasing. Immunological testing and his to pathological examination now increased detection. Diarrhea, bloating and gas abdomen, weight loss remain chief complaints of patients with celiac disease. Nutritional deficiency depends on site and extent of involvement of small gut. Villousatrophy in small intestine is responsible for malabsorption. In cases where there is less involvement of duodenum and proximal jejunum, Iron folate and Calcium absorption is hampered due to situation of high affinity transport mechanisms in these areas. Bone mass loss, macrocytic anemia or iron deficiency anemia are the consequential clinical presentations. Nutritional evaluation is done for patients include anthropometric measurements to hematological levels of nutrients and related evaluations. Six key elements are recommended for management of celiac disease (CELIAC),Consultation with a trained dietician, Education on the disease, Life long gluten free diet, Identification of nutritional deficiencies, Access to reputable support group and Continuous follow-up. Gluten-free Diet excludes the grains wheat, barley and rye. Other grains are non-toxic unless contaminated with wheat or barley and rye. Strict monitoring is thus needed for children with celiac disease and are monitored for adherence to gluten free diet, nutritional status and other such complications of celiac disease. Celiac disease is though not very common but a suspected case should always be investigated for celiac disease as per routine and specific investigations. A strict gluten free diet is advised and it should be monitored regularly. Regular monitoring of patients with clinical assessment and other investigations must be done. Consequential clinical manifestations must be taken care of accordingly. Aregular GFD is necessary for disease. Patient should be counseled regarding regular check up and diet plans.

Keywords

Celiac Disease, Gluten Free Diet, Awareness.

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Sat Pal ¹, Neena Mishra ², Priti Singh ³, Praveen Prashant ⁴

Affiliations
1 Pt. B D Sharma PGIMS, Rohtak, IN
2 Dept. of Physiology, Pt. B D Sharma PGIMS, Rohtak, IN
3 Dept. of Psychiatry, Pt. B D Sharma PGIMS, Rohtak, IN
4 BPSGMCW Khanpur Kalan, IN

Abstract

Introduction: - Heart Rate Variability (HRV) is a noninvasive technique to measure parasympathetic activities of heart. In this study, we measured the Parasympathetic activity in newly diagnosed patients of moderate depression by High Frequency (HF) parameter of HRV. Depression is the leading cause of mental disability and by the year 2020, depression is projected to reach 2nd place of the ranking of disease disability-adjusted life year (DALY).

Objective: Parasympathetic activity in newly diagnosed patients of moderate depression.

Method:- this study was planned on 40 newly diagnosed male patients of moderate depression according to ICD-10 (the international classification of diseases-10) taken from department of Psychiatry PGIMS Rohtak and 40 healthy males subjects of same age group. High Frequency (HF) parameter of HRV was recorded by using RMS polyrite machine.

Result: - The HF (ms²) component in frequency domain of HRV in patients of moderate depression in group II (166.55±41.48) compared to normal subject in group I (179.48±41.68) which reduced but not significantly. The HF expressed in normalized unit (HFnu) and group II (35.30±12.58) were compared to Group I (38.74±1276) and which reduced but not significantly. And HF expressed in power percent (HFpp) and values of group II (18.83±5.04) were compared to the Group I (20.58±5.02), the reduction was not significant.

Conclusion:-We found that Parasympathetic activity was not reduced significantly in patients of moderate depression. So the parasympathetic activity is not a problem to cause cardiac disease in patients of moderate depression.

Keywords

Patients of Moderate Depression, Heart Rate Variability, Parasympathetic Activity.

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