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Rahul Jodh ¹, Mukund Tawar ¹, Prashant Burange ¹, Vedanshu Malviya ¹

Affiliations
1 Department of Pharmacology, P.R. Pote Patil College of Pharmacy, Amravati – 444602, IN

Abstract

In The family Orchidaceae, The plant Dactylorhiza hatagirea (D.Don) Soo, is recognized worldwide for its multi-fold benefits. Dactylorhiza hatagirea (D.Don) Soo Traditionally it used to cure various diseases like dysentery, diarrhoea, chronic fever, cough, stomach-ache, wounds, cuts, burns, fractures, general weakness. Dactylorhiza hatagirea (D. Doon) Soo frequently known as Hatajari and Salampanja in the region of Himalaya. Dactylorhiza hatagirea (D. Doon) Soo is a terrestrial orchid found in moderate climate in the alpine and sub-alpine region Indian Himalaya from 2800-4200 m above from sea level its Occurrence also present in Pakistan, Afghanistan, Nepal, Tibet and Bhutan In India, it predominantly found in region of Jammu and Kashmir, Sikkim, Arunachal Pradesh, Uttarakhand and Himachal Pradesh. Dactylorhiza hatagirea (D. Doon) Soo is collected chaotically from nature due to its high economic demand. the plant consist of different active compound which are responsible for various activity attributed on the plant. the present review emphasis on pharmacological activity of Dactylorhiza hatagirea (D. Doon) Soo which is establish by different authors.

Keywords

Dactylorhiza hatagirea (D. Doon) Soo, Himalayan Orchid, Salam Panja, Metformin

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Vedanshu Malviya ¹, Mukund Tawar ², Prashant Burange ³, Rahul Jodh ³

Affiliations
1 Department of Pharmaceutics, P.R. Pote Patil College of Pharmacy, Amravati – 444602., IN
2 Department of Pharmaceutical Chemistry, P.R. Pote Patil College of Pharmacy, Amravati – 444602., IN
3 Department of Pharmacology, P.R. Pote Patil College of Pharmacy, Amravati – 444602., IN

Abstract

Resveratrol can be recognized as a best nutraceutical. Resveratrol is a novel nutraceutical in which not many details are known therefore an attempt was made to review the details which may be used for the further research. Resveratrol is known to be a polyphenol named as stilbenoid group which is a phytoalexin secreted by more than 70 plant species which is having many pharmacological activities like anticancer, anti-inflammatory, anti-ageing, neuroprotective, cardioprotective, anti-microbial and etc. This natural table top food has a lower bioavailability with lower aqueous solubility. From this review we can conclude that resveratrol is a unique complex having various properties with lots of other benefits.

Keywords

Resveratrol, Natural Phenol, Phytoalexin, Grape Skin, Stilbenoid.

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Rahul Jodh ¹, Mukund Tawar, ¹, Prashant Burange ¹, Pradyumna Keche ¹

Affiliations
1 Department of Pharmacology, P.R. Pote Patil College of Pharmacy, Amravati – 444602., IN

Abstract

Immunoglobulin’s are heterodimeric proteins composed of two heavy (H) and two light (L) chains. They can be separated functionally into variable (V) domains that binds antigens and constant (C) domains that specify effectors functions such as activation of complement or binding to Fc receptors. The variable domains are created by means of a complex series of gene rearrangement events, and can then be subjected to somatic hypermutation after exposure to antigen to allow affinity maturation. Immunoglobulin is the antibodies and glycoprotein’s molecules produced by plasma cells or white blood cells, a signal production occur due the reaction with B cells. In 20th century the science of immunoglobulin was considered as an important science, centrifugation, Immuno adsorption such novel techniques was discovered for dissection of human blood components such as antibodies, so the naming of antibodies was necessary, Latin terms was used at that time for the purpose of naming. But the various in vitro studies shows that the pepsin and acidic condition shows a degradative effect on immunoglobulin neutralizing titer. To overcome this the IgY antibodies are encapsulated. For the protection of mucosal membrane of the IgA plays an essential role, the immune response of the secretory IgA is short lived due to this the genetically engineered antibodies are used for passive immunotherapy.

Keywords

Immunoglobulin, Antibodies, Glycoprotein, Novel Techniques, Immunogens.

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