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P. Muthukumaran ¹, S. Salomi ¹, R. Umamaheshwari ¹

Affiliations
1 P.G .Department of Biochemistry, Meenakshi Chandrasekaran College of Arts And Science, Pattukkottai-614 626, Thanjavur, Tamil Nadu, IN

Abstract

The aim of this study was to investigate the antioxidant effect of Premna serratifolia Linn . The antioxidant activity was evaluated by various antioxidant assays, including 1, 1-diphenyl-2- picrylhydrazyl (DPPH), 2, 2’-azino-bis (3- ethylbenzthiazoline-6-sulfonic acid) (ABTS), and hydrogen peroxide scavenging method. The antioxidant activities were compared to standard antioxidant ascorbic acid. Premna serratifolia Linn wood extract showed a significant antioxidant activity in DPPH, ABTS and H2O2 scavenging methods. The findings of the present study suggest that Premna serratifolia Linn could be a potential source of natural antioxidant that could have greater importance as therapeutic agent in preventing or slowing oxidative stress related degenerative diseases.

Keywords

Premna Serratifolia Linn, Antioxidant Activity.

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P. Muthukumaran ¹, S. Salomi ¹, R. Umamaheshwari ¹

Affiliations
1 P.G. Department of Biochemistry, Meenakshi Chandrasekaran College of Arts and Science, Pattukkottai-614 626, Thanjavur, Tamil Nadu, IN

Abstract

The aim of this study was to investigate the antioxidant effect of Premna serratifolia Linn. The antioxidant activity was evaluated by various antioxidant assays, including 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS), and hydrogen peroxide scavenging method. The antioxidant activities were compared to standard antioxidant ascorbic acid. Premna serratifolia Linn wood extract showed a significant antioxidant activity in DPPH, ABTS and H₂O₂ scavenging methods. The findings of the present study suggest that Premna serratifolia Linn could be a potential source of natural antioxidant that could have greater importance as therapeutic agent in preventing or slowing oxidative stress related degenerative diseases.

Keywords

Premna serratifolia Linn, Antioxidant Activity

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G. A. Sathishkumar ¹, K. Boopathy Bagan ², P. Muthu Kannan ³, V. Palanisamy ⁴, P. Muthukumaran ¹

Affiliations
1 Department of Electronics and Communication Engineering, Sri Venkateswara College of Engineering, Sriperumbudur-602108, IN
2 Department of Electronics, Madras Institute of Technology, Chrompet, Chennai-44, IN
3 School of Electrical Sciences, VIT University, Vellore, IN
4 Department of Computer Science and Engineering, Alagappa University, Karaikudi, IN

Abstract

In today's modern world, wireless technologies have become increasingly popular in our everyday business and personal lives. Personal digital assistants (PDA) allow individuals to access calendars, e-mail, phone number lists, address and the Internet. Some Vendors even provide global positioning system (GPS) capabilities that can pinpoint the location of the device anywhere in the world. In the coming years wireless technologies promise to offer even more features and functions for the future generation. An increasing number of government agencies, businesses, and home users are using, wireless technologies in their environments. An important point here is agencies should be aware of the security risks associated with wireless technologies. Agencies need to develop strategies that will mitigate risks as they integrate wireless technologies into their computing environments. This paper discusses a simple TV scanning technique based on MISO system for wireless communication technologies, outlines the associated antenna design, and offers good resistance to the vulnerabilities in the channel.

Keywords

MISO, Scanning, PN Sequence, BBS Generator, Antenna, Interlaced Scanning, Encryption, FFT, CGSN, SGSN.

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S. Salomi ¹, P. Muthukumaran ¹, R. Umamaheshwari ¹

Affiliations
1 P.G .Department of Biochemistry, Meenakshi Chandrasekaran College of Arts and Science, Pattukkottai-614 626, Thanjavur, Tamil Nadu, IN

Abstract

AIM: The aim of this study was to investigate the antioxidant effect of Azima tetracantha (Salvadoraceae). The antioxidant activity was evaluated by various antioxidant assays, including 1, 1-diphenyl-2- picrylhydrazyl (DPPH), 2, 2’-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS), and hydrogen peroxide scavenging method. The antioxidant activities were compared to standard antioxidant ascorbic acid. Azima tetracantha (Salvadoraceae) extract showed a significant antioxidant activity in DPPH, ABTS and H₂O₂ scavenging methods. The findings of the present study suggest that Azima tetracantha (Salvadoraceae) could be a potential source of natural antioxidant that could have greater importance as therapeutic agent in preventing or slowing oxidative stress related degenerative diseases.

Keywords

Azima tetracantha (Salvadoraceae), Antioxidant Activity.

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P. Muthukumaran ¹, R. Janani ¹

Affiliations
1 Department of Biotechnology, Kumaraguru College of Technology, Coimbatore, Tamil Nadu - 641 049, IN

Abstract

The present study deals with isolation, identification and characterization of heavy metal resistant bacteria isolated from effluent of Ezar Tanneries, Vaniyambadi, Vellore district, South India. Initially, a total of 11 bacterial isolates were screened on Luria Bertani (LB) agar plates supplemented with 5 mg/l concentration of five different heavy metal ions such as Cr, Cu, Ni, Pb and Zn separately. A best microorganism was selected based on high level of heavy metal tolerance. On the basis of morphological, biochemical characterization, the isolates were identified as Staphylococcus aureus. The identified isolates were resistant to Cu and Pb. Staphylococcus aureus showed optimum growth at 30°C and pH 6.5. The identified heavy metal resistant Staphylococcus aureus could be useful for the bioremediation of heavy metal contaminated sewage and waste water.

Keywords

Tannery Effluent, Lead (Pb), Staphylococcus aureus and Bioremediation.

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M. Elayarani ¹, P. Shanmuganathan ¹, P. Muthukumaran ¹

Affiliations
1 Department of Biochemistry and Microbiology, Meenakshi Chandrasekaran College of Arts and Science, Pattukkottai, Thanjavur, Tamil Nadu, IN

Abstract

The present study was carried out in In-vitro antioxidant effects of the Petroleum Ether, Ethanol, and Methanolic flower extracts of Cassia auriculata L . The powder of flower of Cassia auriculata L was extracted sequentially with petroleum ether, ethanol and methanol using Soxhlet extractor and it was subjected to preliminary phytochemical studies for the identification of phytoconstituents by chemical tests. Antioxidant activity of the extract was evaluated by using Diphenyl picryl hydrazyl (DPPH) radical scavenging, and reducing power methods. The extracts of Cassia auriculata L had shown good DPPH (1, 1-diphenyl-2-picryl-hydrazyl) radical scavenging activity. BHA was used as standard antioxidant and positive control. The DPPH radical scavenging activity of the extracts was increased with the increasing concentration, the reducing power of extracts was carried out with ascorbic acid as a standard reducing agent. The Methanolic extract of Cassia auriculata L exhibited higher scavenging and reducing power than the other extracts. All the analysis was made with the use of UV Visible Spectrophotometer (Systronics 117, India). The observation suggest that the flower of Cassia auriculata L extracts has potent dose dependent anti oxidant activity, thus the Ethanobotanical claim of the plant being used in the cardio vascular disorder, muscle build up, nephro protection, anti inflammatory and as an aphrodisiac may be in part due to the antioxidant activity and also the presence of saponins and traces of Flavanoids ascertains that the Anti-oxidant activity.

Keywords

Cassia auriculata L , Antioxidant, Reducing Power, DPPH, BHA, Ascorbic Acid.

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K. Pattabiraman ¹, P. Muthukumaran ²

Affiliations
1 Department of Siddha Medicine, Tamil University, Vakaiyur, Thanjavur - 613 010, Tamilnadu, IN
2 Meenakshi chandrasekaran arts and Science College, Pattukkottai 614 626, Thanjavur, Tamilnadu, IN

Abstract

The aim of the study is to analyse the antioxidant effect of oral administration of aqueous extract of Morinda tinctoria (MTR) fresh fruits on blood glucose, haemoglobin, glycosylated haemoglobin, plasma insulin, antioxidant enzymes and lipid peroxidation in liver and kidney to streptozotocin (STZ)-induced diabetic rats. Aqueous extract of Morinda tinctoria (MTR) on blood glucose, haemoglobin, glycosylated haemoglobin, plasma insulin, serum lipid and the levels of lipid peroxides and antioxidant enzymes, such as catalase, superoxide dismutase, glutathione peroxidase and reduced glutathione, were examined in the liver and kidney tissues of control and experimental groups. Oral administration of Morinda tinctoria (MTR) aqueous extract to diabetic rats for 30 days significantly reduced the levels of blood glucose, lipids and lipid peroxidation, but increased the activities of plasma insulin and antioxidant enzymes, like catalase, superoxide dismutase, reduced glutathione and glutathione peroxidase. The Morinda tinctoria (MTR) aqueous extract supplementation is useful in controlling the blood glucose level, improves the plasma insulin, lipid metabolism and is beneficial in preventing diabetic complications from lipid peroxidation and antioxidant systems in experimental diabetic rats; therefore, it could be useful for prevention or early treatment of diabetes mellitus.

Keywords

Morinda tinctoria (MTR), Antioxidant, Blood Glucose, Diabetes Mellitus, Free Radicals, Oxidative Stress.

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R. Malathi ¹, A. Cholarajan ², K. Karpagam ¹, K. R. Jaya ¹, P. Muthukumaran ³

Affiliations
1 Department of Biotechnology, Bharathidasan University College (w), Orathanadu, Thanjavur, Tamilnadu, IN
2 Department of Microbiology, Meenakshi Chandrasekaran College of Arts and Science, Pattukkottai – 614 626, Thanjavur, Tamilnadu, IN
3 Department of Biochemistry, Meenakshi Chandrasekaran College of Arts and Science, Pattukkottai – 614 626, Thanjavur, Tamilnadu, IN

Abstract

Medicinal plants contribute in human health care system. Most of the plants utilizes by village people as a folk medicine. Now we are turned in to medicinal plant analysis of active compounds and conservation aspect. In the present study we had select the three important medicinal plants. We have collected three medicinally important medicinal plants such as Coleus amboinicus, Phyla nodiflora and Vitex negundo for antimicrobial studies. The experiment carried out in the selected medicinal plants leaves. The results are discussed with the available literature.

Keywords

Antimicrobial Activity, Pathogens, Coleus amboinicus, Phyla Nodiflora and Vitex Negundo.

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J. Kasthuri ¹, A. Cholarajan ¹, R. Vijayakumar ², P. Muthukumaran ³

Affiliations
1 P.G Department of Microbiology, Meenakshi Chandrasekaran College of Arts and Science Karambayam - 614 626, Thanjavur Dt., Tamilnadu, IN
2 Department of Microbiology, Bharathidasan University College for Women, Orathanadu-614 625, Thanjavur District, Tamil Nadu, IN
3 P.G Department of Biochemistry, Meenakshi Chandrasekaran College of Arts and Science ,Karambayam - 614 626, Thanjavur Dt., Tamilnadu, IN

Abstract

The coir industry is one of the major agro-based industries contributing significantly to the national income. This work deals with the characteristics of the waste water discharged from the coir industry. The results presented here are the physical, chemical and microbiological analysis of the waste water samples collected from the coir industry. The analysis indicates the Biochemical Oxygen Demand (BOD), Chemical Oxygen Demand (COD) and nutrient such as nitrate, nitrite, ammonia, calcium and magnesium were recorded high amount and a microbial populations including bacteria, fungi and algae in the waste water.

Keywords

Coir Pith, Physico-Chemical Properties, Bacteria, Fungi, Algae.

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P. Muthukumaran ¹, C. Abirami ², Priyatharsini ²

Affiliations
1 P.G Department of Biochemistry, Meenakshi Chandrasekaran Arts and Science College, Karambayam , Pattukkottai 614 626, Thanjavur, Tamilnadu, IN
2 P.G Department of Biochemistry, Meenakshi Chandrasekaran Arts and Science College, Karambayam, Pattukkottai 614 626, Thanjavur, Tamilnadu, IN

Abstract

Antioxidants play an important role in inhibiting and scavenging free radicals, thus providing protection to human against infections and degenerative diseases. Current research is now directed towards natural antioxidants originated from plants due to safe therapeutics. Azima tetracantha Lam is used in Indian traditional medicine for a wide range of various ailments. To understand the mechanism of pharmacological actions, antioxidant properties of the Azima tetracantha Lam leaves extract were tested using standard in vitro models. The ethanolic extract of Azima tetracantha Lam exhibited strong scavenging effect on superoxide, nitric oxide radical and reducing power radical scavenging assay. The free radical scavenging effect of Azima tetracantha Lam extract was comparable with that of the reference antioxidants. The data obtained in the present study suggests that the extract of Azima tetracantha Lam leaves have potent antioxidant activity against free radicals, prevent oxidative damage to major biomolecules and afford significant protection against oxidative damage.

Keywords

Azima tetracantha Lam , Antioxidant, Ethanolic Extract.

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P. Shanmuganathan ¹, P. Muthukumaran ²

Affiliations
1 Meenakshi Chandra Sekaran College of Arts and Science, Pattukkottai-614 626, Tamil Nadu, IN
2 Department of Biochemistry, Meenakshi Chandra Sekaran College of Arts and Science, Pattukkottai -614 626, Tamil Nadu, IN

Abstract

Antibacterial properties of methanol extract of Cassia auriculata flower was studied on three Gram positive and seven Gram negative bacteria by disc diffusion method. The extract showed zone of inhibition against Gram positive bacteria (Bacillus cereus, B. subtilis and B. megaterium) and Gram negative bacteria [Streptococcus aureus, E. Coli, Salmonella typhae, S. paratyphae, Pseudomonous sp (I), Pseudomonous sp (II) and Shigella sonnei].

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P. Muthukumaran ¹, K. Pattabiraman ²

Affiliations
1 P.G. Dept .of Biochemistry, Meenakshmi Chandrasekaran Arts and Science College, Pattukkottai 614 601, Thanjavur, IN
2 Department of Siddha Medicine, Tamil University, Vakaiyur, Thanjavur - 613 010, Tamilnadu, IN

Abstract

The anti ulcer effects of aqueous, chloroform and ethanol extracts prepared from the Ipomoea aquatica forsk leaves was evaluated in rats employing the pylorus ligation, stress induced and aspirin induced models. The parameters taken to assess anti ulcer activity were volume of gastric juice, free acidity, total acidity and ulcer index. The results indicated that chloroform extract significantly (p<0.001) decreased the volume of gastric acid secretions, free acidity and total acidity and ulcer index.

Keywords

Ipomoea aquatica forsk Antiulcer Effect, Pylorus ligation, Aspirin, Stress.

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P. Muthukumaran ¹, P. Padmapriya ¹, S. Salomi ¹, R. Umamaheshwari ¹, P. Kalaiarasan ¹, C. Malarvizhi ¹

Affiliations
1 P.G. Department of Biochemistry, Meenakshi Chandrasekaran College of Arts and Science, Pattukkottai-614626, Thanjavur, Tamil Nadu, IN

Abstract

The leaf powder of Mimosa pudica, Psidium guajava and Ipomoea aquatica forsk leaves were investigated against different spices of Gram negative bacteria i.e Shigella sonnei, Pseudomonas aeruginosa, Salmonella typhi, Escherichia Coli and fungi are Aspergillums niger, Candida albicans. The screening was performed by standard disc diffusion method. The leaf extract exhibited the highest antibacterial activity against E. Coli with 15±3mm zone of inhibition and for fungi the leaf extract have more anti fungal activity on Aspergillus niger 14±1mm zone of inhibition.

Keywords

Anti Microbial Activity, Gram Negative Bacteria, Fungi, Disc Diffusion Method.

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P. Muthukumaran ¹, P. Shanmuganathan ¹, C. Malathi ¹

Affiliations
1 Meenakshi Chandrasekaran Arts and Science College, Dept. of Life Sciences, Pattukkottai-614626, Thanjavur, Tamilnadu, IN

Abstract

The study of free radicals and antioxidants in biology is producing medical revolution that promises a new age of health and disease management. The present study was performed to evaluate the in vitro antioxidant effect of the ethanolic extract of Mimosa pudica (Mimosaceae) against free radical damage by different standard methods such as DPPH (1,1-diphenyl-2-picrylhydrazyl), Nitric Oxide (NO), ABTS (2,2'-azino-bis (3-ethylbenzthiazoline-6-sulphonic acid)) and Hydrogen peroxide free radical model. The test extract exhibited significant inhibition in Nitric oxide and DPPH free radical formation with IC50 values of 78.1±1.75 and 35.00±1.15 μg/ml respectively. Whereas in the cases of ABTS and Hydrogen peroxide free radicals IC50 values of 81.00±3.85 and 449.60±2.55 μg/ml. Out of these four free radicals the extract showed potent activity on Nitric oxide and DPPH, which is compared to that of ascorbic acid and rutin taken as standards.

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P. Muthukumaran ¹, T. Paramasivan ¹, M. Priya ¹, S. Abarna ¹, P. Ramalingam ¹, N. Saraswathy ¹

Affiliations
1 Department of Biotechnology, Kumaraguru College of Technology, Coimbatore, Tamil Nadu - 641 049, IN

Abstract

In this study, decolorization of three different reactive dyes reactive red 120, reactive black 5 and direct red 81 by two fungal isolates such as Penicillium chrysosporium and Penicillium simplicissimum were carried out by using Bushnell and Haas broth containing 500 mg/l concentration. The effect of physiochemical conditions (Temperature, pH, carbon and nitrogen source, shacking vs static) on the decolorization potential of Penicillium chrysosporium and Penicillium simplicissimum were investigated. Among these two Penicillum species, Penicillium chrysosporium shows maximum % of dye decolorization efficiency then Penicillium simplicissimum. Penicillium simplicissimum decolorize maximally (92% of reactive black 5 at 30ᵒC) similarly, Penicillium chrysosporium (88% of Reactive black 5 and direct red 81 at 30ᵒC). The effect of pH was also tested and found that highest % of decolorization was observed Penicillium simplicissimum (92% of reactive black 5) and Penicillium chrysosporium (87% of Reactive black 5 and direct red 81) by at pH 6. Effect of C:N ratio, highest % of decolorization was observed Penicillium simplicissimum (76% of reactive black 5) and Penicillium chrysosporium (74% of Reactive black 5) at C:N ratio of 1:2. In case of static and shaking condition, shaking condition shows maximum % of dye decolorizing efficiency. For Penicillium chrysosporium (73-88%) and Penicillium simplicissimum (64-91%). This study confirmed the potential of dye decolorizing efficiency of Penicillium chrysosporium and Penicillium simplicissimum and scope for further analysis of performance of treatment of textile effluent.

Keywords

Effluent, Biodecolorization, Reactive Dyes, Penicillium chrysosporium, Penicillium simplicissimum.

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