A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Mehrpour, Omid
- Factors Related to Suicide Attempts by Poisoning in Iranian Children
Authors
1 Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IR
2 Department of Medical Toxicology and Forensic Medicine, Ardabil University of Medical Sciences, Ardabil, IR
3 Department of Neurosurgery, Shahid Beheshti University of Medical Sciences, Tehran, IR
4 Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran
5 Medical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand, IR
Source
Indian Journal of Forensic Medicine & Toxicology, Vol 7, No 1 (2013), Pagination: 129-132Abstract
Objective: Suicide is a major health problem especially in children. Even a large proportion of healthy children have thought about suicide attempt. Some factors are suggested as risk factors for suicide attempt among children such as prior suicide attempt as the most important risk factor. This study was designed to find out why children attempt suicide.Methods: In a descriptive study we assessed all the 6-15 years old children with suicide attempt referred to Loghman Hakim Poison Centre. For each child a questionnaire consisted of demographic information, family information and Children's Suicide Questionnaire were completed by 2 psychiatrists and 2 psychologists.
Finding: 292 children were evaluated with the mean age of 12±1.46 years old ranging from 6 to 15 years old . 81.8% of subjects were female and 18.2% were male. It demonstrates that a higher proportion of the cases reported a history of mental illness in the family (41%). The survey of CSQ information indicated that 28% of the cases suffered from depression and 27.1% had an epileptic seizure. Family argument was present in 36.6% of the cases. 85.4% of the children attempted suicide by using pharmaceutical drugs and 55.5% of suicide attempts were at 6 p.m. to 12 p.m.
Conclusion: Mental or physical illness, living with a mentally ill family member, residing in an economically deprived neighborhoods and lack of access to proper psychiatric care in combination can induce a suicidal attempt so a multidisciplinary approach is necessary in evaluating a suicide attempt in a child.
Keywords
Children, Suicide, Iran. Children's Suicide Questionnaire. (CSQ)References
- Wasserman D, Tran Thi Thanh H, Pham Thi Minh D, Goldstein M, Nordenskiöld A, Wasserman C: Suicidal process, suicidal communication and psychosocial situation of young suicide attempters in a rural Vietnamese community. World Psychiatry 2008; 7:47-53.
- Jackson J, Nuttall RL: Risk for preadolescent suicidal behaviour: an ecological model. Child Adol Soc Work J 2001; 18:180-203.
- Caley M, Fowler T: Suicide prevention: is more demographic information the answer? J Public Health (Oxf) 2009; 31):95-7.
- Barker P: Basic Child Psychiatry. 6th ed. Oxford: Blackwell Scientific. 1995; 11-25.
- Suominen K, Isometsä E, Ostamo A, Lönnqvist J: Level of suicidal intent predicts overall mortality and suicide after attempted suicide: a 12-year follow-up study. BMC Psychiatry 2004; 4:11.
- Seghatoleslam T, Rezaee O: Suicide among Children in Iran. Iran J Neurol 2006; 5:1-9.
- Mehrpour O, Abdollahi M. Poison treatment centers in Iran. Hum Exp Toxicol. 2012; 31(3): 303-304.
- Janghorbani M, Sharifirad G: Completed and attempted suicide in Ilam, Iran (1995-2002): incidence and associated factors. Arch Iran Med 2005;8:119-26.
- Kirmayer LJ, Boothroyd LJ, Hodgins S: Attempted suicide among Inuit youth: psychosocial correlates and implications for prevention. Can J Psychiatry 1998; 43:816-22.
- Seghatoleslam T, Rezaee O: Shahbeigi S: Suicide in Last decade in Iran. Iran J Neurol 2006; 5; 1-5.
- Lalwani S, Sharma GA, Kabra SK, Girdhar S, Dogra TD: Suicide among children and adolescents in South Delhi (1991-2000). Indian J Pediatr 2004;71:701-3.
- McClure GM: Suicide in children and adolescents in England and Wales 1970-1998. Br J Psychiatry 2001;178:469-74.
- Groholt B. Wichstrom L. Suicide Among Children and Adolescents. J Paediatr 1998; 19:255-65.
- Zhang ZQ, Guo LT: A cross-sectional study on suicide attempts in urban middle school students in Chengdu Zhonghua Liu Xing Bing Xue Za Zhi 2003;24:189-91.
- van der Kolk BA, Perry JC, Herman JL:Childhood origins of self-destructive behavior. Am J Psychiatry 1991; 148:1665-71.
- Shaffer D, Gould MS, Fisher P, Trautman P, Moreau D, Kleinman M, Flory M: Psychiatric diagnosis in child and adolescent suicide. Arch Gen Psychiatry 1996; 53:339-48.
- Farzaneh E, Mehrpour O, Alfred S, Moghaddam HH, Behnoush B, Seghatoleslam T: Self-poisoning suicide attempts among students in Tehran, Iran. Psychiatr Danub 2010; 22:34-8.
- Patel V, Kleinman A: Poverty and common mental disorders in developing countries. Bull World Health Organ 2003; 81:609-15
- Dastgir, S, Kallankesh LR, Pourafkary N, Vahidi RG, Mahmoodzadeh F: Incidence, survival pattern and prognosis of self-immoration: a case study in Iran. J Public Health 2006; 14:2-6.
- Intravascular Haemolysis due to Glucose -6- Phosphate Dehydrogenase Deficiency in a Patient with Aluminum Phosphide Poisoning
Authors
1 Department of Pediatrics, Loghman-Hakim Hospital
2 Department of Clinical Toxicology, Loghman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IR
3 Medical Toxicology and Drug Abuse Research Center (MTDRC), Pasdaran Avenue, Birjand University of Medical Sciences, Birjand, IN
Source
Indian Journal of Forensic Medicine & Toxicology, Vol 7, No 2 (2013), Pagination: 79-81Abstract
Aluminum phosphide (AlP) poisoning and glucose?6?phosphate dehydrogenase (G6PD) deficiency are two common clinical problems in Iran. However, hemolysis associated with AlP poisoning is extremely rare. We report a 24-year-old G6PD deficient patient with AlP poisoning presenting with intravascular hemolysis.Keywords
G6PD Deficiency, Aluminum Phosphide, HemolysisReferences
- Mehrpour O, Singh S: Rice tablet poisoning: a major concern in Iranian population Hum Exp Toxicol 2010, 29:701–2.
- Mehrpour O, Jafarzadeh M, Abdollahi M: A systematic review of aluminium phosphide poisoning. Arh Hig Rada Toksikol 2012, 63: 61–73
- Mehrpour O, Singh S: Rice tablet poisoning: a major concern in Iranian population. Hum Exp Toxicol 2010, 29:701–2. 4. Mehrpour O, Keyler D, Shadnia S: Comment on Aluminum and zinc phosphide poisoning. Clin Toxicol (Phila) 2009, 47:838–9.
- Mehrpour O, Alfred S, Shadnia S, Keyler DE, Soltaninejad K, Chalaki N, Sedaghat M Hyperglycemia in acute aluminum phosphide poisoning as a potential prognostic factor. Hum Exp Toxicol 2008, 27:591–5.
- Shadnia S, Mehrpour O, Abdollahi M: Unintentional poisoning by phosphine released from aluminum phosphide. Hum Exp Toxicol 2008, 27:87–9.
- Goldfrank LR, Flomenbaum NE, Lewin NA. Goldfrank’s Toxicologic Emergencies. 7th ed. McGraw –Hill, New York, 2002; 1560.
- Mehrpour O, Abdollahi M. Poison treatment centers in Iran.Hum Exp Toxicol. 2012;31(3): 303-304
- Glader, BE. Glucose-6-phosphate dehydrogenase deficiency and related disorders of hexose monophosphate shunt and glutathione metabolism. Wintrobe’s Clinical Hematology, 10th ed, Lee, GR, Foerster, J, Lukens, J, et al (Eds), Williams & Wilkins, Baltimore, pp. 1176-90.
- Tripathy V, Reddy BM. Present status of understanding on the G6PD deficiency and natural selection. J Postgrad Med. 2007;53(3): 193-202.
- Soltaninejad K, Nelson LS, Khodakarim N, Dadvar Z, Shadnia S. Unusual complication of aluminum phosphide poisoning: Development of hemolysis and methemoglobinemia and its successful treatment.Indian J Crit Care Med 2011;15 (2): 117-9.
- Srinivas R, Agarwal R, Jairam A, Sakhuja V. Intravascular haemolysis due to glucose-6- phosphate dehydrogenase deficiency in a patient with aluminium phosphide poisoning. Emerg Med J 2007;24 (1): 67-8.
- Khurana V, Gambhir IS, Kishore D. Microangiopathic hemolytic anemia following disseminated intravascular coagulation in aluminum phosphide poisoning. Indian J Med Sci 2009;63(6):257-9.
- Shadnia S, Soltaninejad K, Hassanian-Moghadam H, et al. Methemoglobinemia in aluminum phosphide poisoning. Hum Exp Toxicol. 2011;30(3):250-3.
- Aggarwal P, Handa R, Wig N, Biswas A, Saxena R, Wali JP. Intravascular hemolysis in aluminium phosphide poisoning. Am J Emerg Med 1999; 17 (5): 488-9.
- Evaluation of Histopathological Changes in Fatal Aluminum Phosphide Poisoning
Authors
1 Department of Forensic Medicine, Faculty of Medicine, Medical Sciences/University of Tehran, IR
2 Department of Forensic Pathology, Scientific and Educational Research Center of Legal Medicine Organization of Iran, Tehran, IR
3 Department of Forensic Toxicology, Scientific and Educational Research Center of Legal Medicine Organization of Iran, Tehran, IR
4 Loghman Hakim Poison Center, Faculty of Medicine, Medical Sciences/University of Shaheed Beheshti, Tehran, IR
5 Autopsy Service, Scientific and Educational Research Center of Legal Medicine Organization of Iran, Tehran, IR
Source
Indian Journal of Forensic Medicine & Toxicology, Vol 2, No 2 (2008), Pagination: 34-36Abstract
This study examines histopathological changes of human organs in cases with aluminum phosphide fatal poisoning. The cases with aluminum phosphide fatal poisoning in Tehran Legal Medicine Center over 12 month period starting in March 2006, were studied. Necropsy was performed for all cases and liver, lung, brain, kidney and spleen were collected from all cases and fixed in formaldehyde solution (37% formalin).Tissue specimens were taken from organs and processed by routine histological method. Then any histhopathological changes were recorded by pathologist. In gross examination, almost all the vital organs were found to be congested. In microscopic study, the most frequent histopathological findings in liver were central venous congestion, degeneration of hepatocytes and mononuclear infiltration. In lung, alveolar thickening, and dilated capillaries were detected. Findings in the brain tissue revealed degenerated Nissel granule in the cytoplasm and deeply stained degenerated eccentric nucleus in brain cortex. Changes in the kidney included glomerulus's and intraparanchymal congestion. These findings indicated that histopathological changes are common in aluminum phosphide fatal poisoning.Keywords
Aluminum Phosphide, Histopathology, Fatal Poisoning.References
- Abdollahi M, Jalali N, Sabzevari O, Hoseini R, Ghane T. A retrospective study of poisoning in Tehran. J Toxicol Clin Toxicol, 1997; 35:387-93.
- Abdollahi M, Jalali N, Sabzevari O, Nikfar S, Fallahpour M. Pesticide poisoning during an 18-month period (1995- 1997) in Tehran, IRAN. Irn J Med Sci, 1999; 24: 77-81.
- Nikfar S, Abdollahi M, Cheraghali A. Going from strength to strength; A drug and poison information centre. Essent Drugs Monit 2000; 28: 30-31.
- Soltaninejad K, Faryadi M, Sardari F. Acute pesticide poisoning related deaths in Tehran during the period 2003-2004. J Forensic Leg Med, 2007; 14(6):352-54.
- Shadnia S, Rahimi M, Pajoumand A, Rasouli MH, Abdollahi M. Successful treatment of acute aluminum phosphide poisoning: possible benefit of coconut oil. Hum Exp Toxicol 2005; 24: 215-18.
- Pajoumand A, Jalali N, Abdollahi M, Shadnia S. Survival following severe aluminum phosphide poisoning. J Pharm Pract Res, 2002; 32: 297-99.
- Gupta S, Ahlawat SK. Aluminum phosphide poisoning, a review. J Toxicol Clin Toxicol, 1995; 33: 19-24.
- www.inchem.org/documents/pims/chemical/pim865.htm
- Singh S, Bhalla A, Verma SK, Kaur A, Gill K. Cytochrom-C oxidase inhibition in ALP poisoned patients. Clin Toxicol (phila) 2006; 44(2):155-58.
- Chugh SN, Dushyant Ram S ,Arora B, Malhotra GC. Incidence and outcome of aluminum phosphide poisoning in a hospital study. Indian J Med Res, 1991; 94:232-35.
- Sinha US, Kapoor AK, Singh AK, Gupta A, Mehrotra R. . Histopathological changes in cases of aluminum phosphide poisoning. Indian J Pathol Microbiol, 2005; 48(2):177- 80.
- Okolie NP, Aligbe JU, Osakue EE. Phostoxin-induced biochemical and pathomorphologiacal changes in rabbits. Indian J Exp Biol, 2004; 42(11): 1096-99.
- Arora B, Punia RS, Kalra R Histopathological changes in aluminum phosphide poisoning. J Indian Med Assoc, 1994; 93:380-81.
- Siwach SB, Yadav DR, Arora B, Dalal S, Jagdish .Acute aluminum phosphide poisoning: An epidemiological clinical and histopathological study. J Assoc Physicians India, 1988;36:594-6.
- Saleki S, Ardalan FA, Javidan-Nejad A. Liver histopathology of fatal phosphine poisoning. Forensic Sci Int, 2007; 166(2-3):190-93.
- Singh S, Singh D, Wig N, Jit I, Sharma BK. Aluminum phosphide ingestion—a clinico-pathologic study. J Toxicol Clin Toxicol, 1996; 34(6):703-6.
- Siwach SB, Dua A, Sharma R, Sharma D, Mehla RK. Tissue magnesium content and histopathological changes in non-survivors of aluminum phosphide poisoning. J Assoc Physicians India, 1994; 43:676-78.
- Siwach SB, Gupta A. The profile of acute poisoning in Harajana-Rohtak study. J Assoc Physician India, 1995; 43: 756-59.