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Sahi, Nita
- Oxidative Stress in Relation to Obesity in Gujrati and Non Gujarati Young Girls before and after Maize Diet
Authors
1 Biochemistry, Pacific University, Udaipur,Rajasthan, IN
2 Biochemistry, RNT Medical College, Udaipur, Rajasthan, IN
3 Pharmacology, GIDSR, Ferozepur, IN
4 Oral and Maxillofacial Pathology, Luxmi Bai Institute of Dental Sciences and Hospital, Patiala, Punjab, IN
Source
International Journal of Medical and Dental Sciences, Vol 3, No 1 (2014), Pagination: 314-324Abstract
Background: Obesity is the first of the "diseases of civilization" to appear. Its prevalence is escalating at an alarming rate. Environmental and behavioral changes brought about by economic development, modernization and urbanization has been linked to the rise in global obesity. Obesity may induce systemic oxidative stress.
Objective: The present scenario suggests that higher oxidative stress is the key factor of obesity and hence a management strategy aiming at control of lipid peroxidation in obesity by use of maize diet is envisaged.
Material and methods: This study has been conducted on 1001 Gujarati and non Gujarati girls aged between 18-30 years. They were further distributed according to age, inhabitance, socio economic status, dietary habits, family history and blood pressure. Every subject in each group was asked to replace the wheat chapatti by maize chapatti for 30 days; the girls were examined for oxidative stress parameter MDA before and after maize diet along with the statistical evaluation.
Results: There was a positive effect of maize diet on biochemical parameter of all the girls in all the subgroups Malondialdehyde level in total girls before the maize diet was 2.35 ± 0.76nmol/ml which reduced to 1.8 ± 0.46nmol/ml after the diet (P<0.001).
Conclusions: The oxidative stress showed improvement in normal, overweight and obese girls, most significantly on overweight and obese girls after taking the diet (P<0.001). Current dietetic practice is to recommend a healthy eating plan of reduced fat, and increased fiber intake.
Keywords
Obesity, Prevalence, Oxidative Stress, Malondialdehyde (MDA), Dietary Fiber.References
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- Study of Serum Osteocalcin and Serum Adiponectin in Young Healthy Offspring of Diabetic Parents
Authors
1 Department of Biochemistry, Pacific Medical College & Hospital, Udaipur, Rajasthan, IN
Source
Indian Journal of Health and Wellbeing, Vol 10, No 1-3 (2019), Pagination: 21-25Abstract
With the increasing prevalence of diabetes all over the world, it is required to understand the relation between serum osteocalcin, Adiponectin and measurement o f glucose, insulin level in off-spring o f diabetic patient, also correlating measure o f insulin resistance. We have also compared serum osteocalcin level and adiponectin level in young healthy offspring o f diabetic with offspring o f healthy parents .our study was carried in department of biochemistry Pacific Medical College And Hospital Udaipur .the conclusion drawn was that serum adiponectin was significantly loe in person who are at genetically high risk for diabetes and serum osteocalcin was inversely correlation o f adiponectin was with blood glucose and insulin .our study exhibit its probable role in future onset of diabetes in such individual.Keywords
Serum Osteocalcin, Serum Adiponectin, Diabetic Parents.References
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- Study of Various Liver Function Oxidative Stress Antioxidant Status in Malnourished Children
Authors
1 Department of Biochemistry, Pacific Medical College & Hospital, Udaipur, Rajasthan, IN
Source
Indian Journal of Health and Wellbeing, Vol 10, No 1-3 (2019), Pagination: 37-42Abstract
Malnutrition is a condition where physical function o f a person is not proper to the point where he can no longer maintain adequate body performance processes. In this respect few studies have been carried so the present study aims to evaluate biochemical markers in young patients suffering from malnutrition. We have evaluated liver function test, CRP as a marker, oxidative stress marker- MDA, antioxidant Ascorbic Acid and Zinc and also correlated with above parameter in severe acute malnutrition. Among 120 subjects, 25 cases + 25 controls were males and 35 cases + 35 controls were females. Biosystems a- 25 fully automated analyzer was used for measurement. A significant negative correlation was between MDA and Total protein and Albumin. A significant positive correlation was between MDA and AST and ALT. A significant negative correlation was seen in levels of ascorbic acid and Zinc and CRP, MDA level was significantly higher while vitamin C, Zinc are significantly low in malnourished children (p< 0.001) results o f our present work provide evidence that oxidative stress is present in sever e malnourished children along with inflammation and hepatic damage Extent o f derangement o f parameters can help to plan specific treatment for malnourished children.Keywords
Malnutrition, Biochemical Markers, Young Patients.References
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