A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
kumari, Neha
- RFID-Context Awareness System
Authors
Source
International Journal of Innovative Research and Development, Vol 2, No 5 (2013), Pagination:Abstract
This paper presents the design and development of a context aware system using RFID technology. This system contains RFID tags RFID reader and a server as the processors and screen monitor at various locations. The objective of this system is to sense the location of the system and urgently deliver message to the user. This paper aims to design and implement an RFID-based reliable and efficient solution to sense the location of system. The wireless LANs are used to communication between the tag reader and the web server. The result of this survey has indicated that the proposed system is efficient and easy to use.
Keywords
RFID (Radio Frequency Identification), Ubiquitous Computing, EPC (Electronic Product Code) tag.- Improving Smell Prediction: Developing an Improved Model with Supervised Learning Techniques
Authors
1 Department of Computer Science and Technology, Central University of Punjab, City Campus, Manasa Road, Bathinda – 151001, Punjab, IN
Source
Indian Journal of Science and Technology, Vol 10, No 24 (2017), Pagination:Abstract
Objectives: To build a model for the prediction of the code smells using the supervised learning techniques. The motive to build code smell prediction model is to propose a model with less false positive code smells. Also, the proposed model is cross validated using 10-fold cross validation Methods/Statistical Analysis: To build a smell prediction model, two code smell detection tools are used i.e. IPlasma and PMD. The metrics are extracted using understand and IPlasma. To achieve the above mentioned objective, two experiments are performed. One is using the code smells of the PMD and the other one is using the smells of the IPLasma. The smells of the PMD are associated with the metrics that are extracted using Understand. Then, the model is trained using the different supervised learning algorithms that are called classifiers i.e. Random Forest, Naïve Bayes and Kstar. Findings: In this research work, two experiments are performed. One is using the code smells of the PMD and other one is using the code smells of the IPlasma. From the results obtained i.e. with the code smells of the PMD, it is concluded that Random Forest predicts small number of false positive and false negative code smells as the precision and Recall of the Random Forest in each dataset is larger than the other two classifier’s. Moreover, the ROC value of Random Forest is higher in some datasets and in some datasets the ROC value of KStar is higher. The results obtained i.e. with the code smells of the IPlasma, it is concluded that again Random Forest predict code smells more correctly than the other two classifiers and give less number of false positive and false negative code smells. Moreover, there is an exception, there is one dataset in which Random Forest and KStar both shows 100% accuracy i.e., Precison and Recall both are equal to 1, which shows that both classifiers predicts no false positive and false negative code smells. Moreover, the ROC value of Random Forest is higher than the other two classifiers, even in some datasets it is equals to 1. Using this it is concluded that Random Forest gives the best code smell predicting model. Application/Improvements: The results of this experiments shows only one case where the false positive and false negative code smells are not predicted by the models. This can improve such that on apply each and every dataset it gives zero false positive code smells.Keywords
Automatic Tools, Bad Code Smells, Code Smell, Code Smell Prediction, Supervised Learning Techniques- Microwave Generated Bionanocomposites for Solubility and Dissolution Enhancement of Poorly Water Soluble Drug
Authors
1 Sri Sai College of Pharmacy, Badhani, Pathankot, Punjab., IN
Source
Asian Journal of Pharmaceutical Research, Vol 12, No 3 (2022), Pagination: 192 - 198Abstract
Drugs that shows complete oral absorption and good bioavailability are soluble in gastrointestinal tract or vice versa. Objective and Method: To enhance the solubility and dissolution of poorly water soluble drug itraconazole. Technique used- Microwave generated bionanocomposites technique. Carriers- Chitosan, β- cyclodextrin and Poly vinyl pyrolidine. Result and Conclusion: The prepared bionanocomposites was evaluated by UV spectroscopy, XRD study, In vitro drug release study and TEM. The results shows that in vitro data obtained for bionanocomposites of itraconazole showed increase solubility in phosphate buffer having pH= 6.8 and the method of preparation of itraconazole found to be simple, reproducible, provide good solubility and drug content. Also it is obtained that there was maximum 23 fold increase in solubility when Poly vinyl pyrolidine used as a carrier in 1:4 and hence considered as effective carrier for crystallization of itraconazole.
Keywords
Bionanocomposites, Nanocomposites, Itraconazole, polymer, solubilityReferences
- Nigal A, Darekar A, Saudagar R. A Review on Nanohybrids: Technique for Solubility Enhancement of Poorly Water Soluble Drugs. Journal of Drug Delivery and Therapeutics. 2019 May, 9(3), page no: 634-640.
- Rabinow BE. Nanosuspensions in drug delivery. Nature reviews Drug discovery. 2004 Sep, 3(9), page no: 785-796.
- Kadu PJ, Kushare SS, Thacker DD, Gattani SG. Enhancement of oral bioavailability of atorvastatin calcium by self-emulsifying drug delivery systems (SEDDS). Pharmaceutical Development and Technology. 2011 Feb, 16(1), page no: 65-74.
- T. yasuhiro, M. Deanna. The biopharmaceutics classification system: sub classes for invivo predictive dissolution methodology and IVIVC. European Journal of Pharmaceutical Sciences. 2014 Jan, 57, page no: 1-47.
- Baka E. Development and examination of solubility measurement methods for drug solubility determination (Doctoral dissertation, Semmelweis University).
- Jouyban A, Fakhree MA. Experimental, computational methods pertaining to drug solubility. Toxicity and Drug testing. 2012 Feb, (1), page no: 187-213.
- Ploehn HJ, Russel WB. Interactions between colloidal particles and soluble polymers. Advances in Chemical Engineering. 1990 Jan, 15, page no: 137-228.
- A. deshmukh, K. tiwari. Solubility enhancement techniques for poorly water-soluble drugs. International Journal of Pharmaceutical Sciences and Nanotechnology. 2017 June, 10(3), page no: 3701-3708.
- Y . thorat, I. gonjari. International journal of pharmaceutical sciences and research. 2011 sept, 2(10), page no: 2501-2513.
- Ruiz-Hitzky E, Darder M, Aranda P. Functional biopolymer nanocomposites based on layered solids. Journal of Materials Chemistry. 2005 sept, 15(35-36), Page no: 3650-3662.
- Shchipunov Y. Bionanocomposites: Green sustainable materials for the near future. Pure and Applied Chemistry. 2012 Oct, 84(12), page no: 2579-2607.
- PP sambarkkar, SL patwekar. International journal of pharmacy and pharmaceutical sciences. 2012 jan, 4(2), page no: 60-65.
- https://en.m.wikipedia.org/wiki/itraconazole
- Takara K, Tanigawara Y, Komada F, Nishiguchi K, Sakaeda T, Okumura K: Cellular pharmacokinetic aspects of reversal effect of itraconazole on P-glycoprotein-mediated resistance of anticancer drugs. Biological Pharmaceutical Bulletin. 1999 Dec, 22(12), page no: 1355-1359.
- Bhat MR. Microwave-generated bio-nanocomposites for Solubility Enhancement of Nifedipine. Asian Journal of Pharmaceutics (AJP). 2016 Dec, 10(04), page no: 1-9.
- Pandey A and Rath B. Pharmaceutical Preformulation Studies with Special Emphasis on Excipients Compatibility Chem Inform. 2012 june, 43(23), page nio: 1029-1048.
- Pavia DL, Lampman GM and Kriz GS. Introduction to Spectroscopy. Harcourt college publishers, Orlando, Florida, USA. 2015 aug, 5, page no 1-786.
- Baka E, Comer JE and Takacs-Novak K. Study of equilibrium solubility measurement by saturation shake-flask method using hydrochlorothiazide as model compound. Journal of Pharmaceutical and Biomedical Analysis. 2008 feb, 46(2), page no: 335-341.
- D. phanchaxari, K. sumit. Enhancement of solubility and dissolution property of griseofulvin by nanocrystallization. International Journal of Drug Development and Research. 2011 may, 3(2), page no: 180-191.
- MR shivalingam, T. jyothibasu. Formulation and evaluation of solid dispersion of glipizide for dissolution rate enhancement. International Journal of Pharmaceutical Research and Development. 2011 mar, page no: 231-239.
- Silva RD, Oliveira TA, Conceição ID, Araque LM, Alves TS, Barbosa R. Evaluation of hydrolytic degradation of bionanocomposites through fourier transform infrared spectroscopy. Polímeros. 2018 Sep, 28(4), page no: 348-354.
- Bhat MR, Sharma S, Chimkode RM, Derkar GK, Sarla RM, Payghan SA. Optimization bio-nanocomposites of fenofibrate for enhancement of solubility and dissolution using microwave induced diffusion technique. International Journal of Applied Research in Science and Engineering, 2016 nov, page no: 209-216.
- Patil AA, Payghan. Bionanocomposites: approach solubility and bioavailability and bioavailability enhancement of poorly water soluble drugs. International Journal of Universal Pharmacy and Biosciences. 2014 aug, 3(4), page no: 258-268.
- Sonawane DD, Jat RK, Pawar AY. Development of microwave generated Nanocomposites for solubility enhancement of BCS class II drug. The Pharma Innovation Journal 2018, 7(12), page no: 270-277.
- M. kale, A. pawar. International Journal of Chem Tech Research. 2018, 11(5), page no: 124-138.
- Shaikh SA. Formulation and development of s-(-)-Amlodipine besylate tablets to improve the dissolution profile. Asian Journal of Pharmaceutics (AJP. 2016 Sep, 1(1), page no: 199-206.