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Authors
Affiliations
1 Department of Oral Pathology, Govt. Dental College and Hospital, Mumbai, Maharashtra, IN
2 Department of Oral Pathology and Microbiology, Center for Dental Education and Research (AIIMS), New Delhi, IN
3 Department of Oral Pathology and Microbiology, SDKS Dental College and Hospital, Nagpur, Maharashtra, IN
4 Department of Oral Pathology and Microbiology, Dr. HSRSM's Dental College and Hospital, Hingoli, Maharashtra, IN
5 Department of Oral Pathology and Microbiology, Saraswati-Dhanwantari Dental College and Hospital, Parbhani, Maharashtra, IN
6 Ministry of Health, BH
Source
Journal of Pierre Fauchard Academy (India Section), Vol 31, No 1 (2017), Pagination: 22-24
Abstract
Pemphigus vulgaris (PV) is an autoimmune blistering disease characterized by circulating pathogenic IgG autoantibodies against desmoglein 3 and desmoglein 1. Oral lesions readily rupture, new bullae developing as the older ones rupture and ulcerate. Oral lesions may precede cutaneous lesions in 53.52% cases. Prompt recognition and diagnosis is critical since it may prevent cutaneous involvement. Systemic steroids remain the gold standard treatment of PV. Their use has transformed what was almost invariably a fatal illness into one whose mortality is now below 10%. We report a case of patient with oral ulcers since 4 months, who is diagnosed with PV without cutaneous involvement.
Keywords
Corticosteroids, Mucous Membrane, Oral Ulcer, Pemphigus Vulgaris.
References
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