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Salman, Mohd
- Formulation, Optimization and Evaluation of Drotaverine HCl Mini Tablet
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Affiliations
1 Department of Pharmaceutics, Ali-Allana College of Pharmacy Akkalkuwa, Dist.: Nandurbar (425415), Maharashtra, IN
1 Department of Pharmaceutics, Ali-Allana College of Pharmacy Akkalkuwa, Dist.: Nandurbar (425415), Maharashtra, IN
Source
Asian Journal of Pharmacy and Technology, Vol 12, No 1 (2022), Pagination: 6-12Abstract
The aim of present research was to develop a mini tablet of Drotaverine hydrocholoride. Mini tablets of Drotaverine hcl were prepared by using various polymers, such as gellan gum and carbopol 940. Mini tablets were evaluated for weight variation, hardness, thickness, friability, drug content, and in-vitro dissolution studies. The prepared mini tablets exhibited satisfactory physic-chemical characteristics. All prepared batches shown good in-vitro dissolution studies. The best result from optimized batches is of F5 which gives drug release 97.72% in 12 h time periods.Keywords
Drotaverine Hcl, Mini Tablet, Optimization, Gellan Gum, Direct CompressionReferences
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- An Overview of Pharmaceutical Mini Tablet
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Authors
Affiliations
1 Department of Pharmaceutics, Ali-Allana College of Pharmacy Akkalkuwa, Dist.: Nandurbar (425415), Maharashtra,, IN
1 Department of Pharmaceutics, Ali-Allana College of Pharmacy Akkalkuwa, Dist.: Nandurbar (425415), Maharashtra,, IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 14, No 1 (2022), Pagination: 94-102Abstract
The objective of controlled drug delivery systems is to decrease the frequency of dosing and to increase the efficiency of the drug by localization. In oral controlled drug delivery systems, Mini-tablets represent the new trend in Solid oral dosage forms are most acceptable dosage forms especially tablets are most widely accepted by people of different age groups. Mini tablets with a diameter alike to or smaller than 3–6 mm. mini tablets are multiple unit dosage forms and are convenient to pellets or any other oral dosage forms as there calm to manufacture and stability snags are less. Some types of mini tablets are like to Oral disintegrating mini tablets, pH responsive mini tablets, Biphasic mini tablets, gastro retentive mini tablets, paediatric mini tablets, and bio adhesive mini tablets.Keywords
Mini Tablet, MUDFs, SUDFs, Compressed mini tablet, Pellets.References
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