Informatics Publishing Limited

Ashok Kumar Tiwari ¹, Neelesh Dwivedi ¹, Manoj Kumar Tripathi ¹, Aakanksha Tiwari ¹, Pawan Kumar Ahirwar ¹, Sharda Prasad Tripathi ¹

Affiliations
1 Ayurveda Sadan, Arogyadham, JRD Tata Foundation for Research in Ayurveda and Yoga Sciences, Deendayal Research Institute, Chitrakoot, Satna, Madhya Pradesh-485334, IN

Abstract

Ayurvedic medicine Kutajastaka Pravahi Kvatha, known to be effective in Daha (burning sensation); Raktatisara (Diarrhoea with blood); Sula (pain); Amadosa; (products of impaired digestion and metabolism) and Sarvatisara (all types of diarrhoea), has been standardized by following modern scientific quality control procedures for the finished product. The results of physico-chemical parameters viz. specific gravity (1.01), total solids (4.45%) and pH (4.50) were found. Microbiological limit test and heavy metals Pb, Cd, As, Hg were also found within the limits set by Ayurvedic Pharmacopiea of India (API). The obtained values can be adapted to lay down new pharmacopoeial standards with batch to batch consistency. The phytochemical constituents found in the raw material used for the preparation of Kutajastaka Pravahi Kvatha facilitate the desirable therapeutic efficacy of the medicinal formulations a whole in elements and also could help in understanding the underlying mechanism of pharmacological action.

Keywords

Standardization, Ayurvedic Formulation, Kutajastaka Pravahi Kvatha, Pharmacopoeial Standards.

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Ashok Kumar Tiwari ¹, Neelesh Dwivedi ¹, Manoj Kumar Tripathi ¹, Sharda Prasad Tripathi ¹

Affiliations
1 Ayurveda Sadan, Arogyadham, JRD Tata Foundation for Research in Ayurveda and Yoga Sciences, Deendayal Research Institute, Chitrakoot, Satna, Madhya Pradesh-485334, IN

Abstract

The present study deals with the quality control of the Ayurvedic formulation Darvyadi Kvatha Ghana Vati (Tablet) following quality control procedures for the finished product. The results of physico-chemical parameters viz. loss on drying (9.7 %), average weight (5.0 %), friability (0.15 %) and disintegration time (85 min) were found. Microbiological limit test and heavy metals Pb, Cd, As, Hg were also found within the limits set by Ayurvedic Pharmacopeia of India (API). The obtained values can be adapted to lay down new pharmacopoeial standards with batch to batch consistency. The phytochemical constituents found in the raw material used for the preparation of Darvyadi Kvatha Ghana Vati (Tablet) facilitate the desirable therapeutic efficacy of the medicinal formulations a whole in elements and also could help in knowing the underlying mechanism of pharmacological action.

Keywords

Ayurvedic Formulation, Darvyadi Kvatha Ghana Vati, Quality Control.

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Ashok Kumar Tiwari ¹, Manoj Kumar Tripathi ¹, Neelesh Dwivedi ¹

Affiliations
1 Ayurveda Sadan, JRD TATA Foundation for Research in Ayurveda & Yoga Science, Arogyadham, Deendayal Research Institute, Chitrakoot, Satna - 485780 (M.P), IN

Abstract

Natural products from plant, animal and minerals have been the basis of the treatment of human disease. India is a vast repository of medicinal plants that are used in traditional medical treatments Herbal medicines as the major remedy in traditional system of medicine have been used in medical practices since antiquity. Medicinal plants play an important role in the development of potent therapeutic agents. To keep this view in mind, a polyherbal Sama Śarkarã Cûrna is formulated in house, which is very effective in stomach disorders, asthma, heart diseases and bronchitis. It formulated using eight single drugs viz Zingiber officinale (rhizome), Piper longum (fruits), Piper nigrum (fruits), Mesua ferrea (Stamen), Cinnamomum tamala (leaf), Cinnamomum zeylanicum (stem bark), Elettaria cardamomum (seeds) and Sita. All the ingredients and curna were analyzed in order to assess the authenticity of the drugs based on ayurvedic requirement following a series of physical-chemical, phyto-chemical, chromatography, microbiological parameters. Herbal medicines are inherently different from conventional pharmacological treatments, but presently there is no way to assess their efficacy other than by currently used conventional clinical trial methodologies, in which efficacy is conventionally assessed by clinical, laboratory, or diagnostic outcomes. Systematic study of herbal drug following quality parameters can improve morbidity, mortality, and of course quality of life. There is, however, scope to utilize the flexibility inherent in the modern scientific method for conducting studies on herbal medicines.

Keywords

Ayurvedic Formulation, Sama Sarkara Cuûrna, Quality Control Parameter.

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