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Sharma, Manjuri
- Clinical Study of Cardiovascular Complications in Chronic Kidney Disease Patients with Special Reference to Echocardiography
Abstract Views :199 |
PDF Views:83
Authors
Affiliations
1 Dept of Nephrology, Gauhati Medical College and Hospital, Guwahati, Assam, IN
2 Gauhati Medical College and Hospital, Guwahati, Assam, IN
3 Department of Nephrology, Gauhati Medical College and Hospital, Guwahati, Assam, IN
1 Dept of Nephrology, Gauhati Medical College and Hospital, Guwahati, Assam, IN
2 Gauhati Medical College and Hospital, Guwahati, Assam, IN
3 Department of Nephrology, Gauhati Medical College and Hospital, Guwahati, Assam, IN
Source
International Journal of Health Research and Medico Legal Practice, Vol 3, No 1 (2017), Pagination: 44-47Abstract
Background: Cardiovascular abnormalities are commonly encountered in patients with chronic kidney disease (CKD) or end stage renal disease (ESRD) and these include left ventricular hypertrophy (LVH), left ventricular dilatation, and left ventricular systolic and diastolic dysfunction. Uremic cardiomyopathy is thought to be the pathological cardiac hypertrophy, indicating the influence of impaired renal function on the myocardium. Cardiovascular complications lead in all causes of mortality among patients with CKD, accounting for approximately 50% of deaths. Method: It was a hospital based study conducted from March 2014 to March 2015 in Guwahati Medical College where CKD patients were evaluated for presence of any cardiovascular morbidity. Results: Cardiomegaly on chest x-ray was present in 64% of the patients. Electrocardiography and 2D echocardiography of patients revealed LVH in76% and 84% of patients. Left ventricular systolic dysfunction (LVSD) was found in 52 % of patient of which 34 % had mild dysfunction (LVEF= 45% -54%) and 18 % had moderate dysfunction (LVEF= 35% -44%). Diastolic dysfunction was found in 54 % of patient. Conclusion: Cardiovascular complications are common in patients with chronic kidney disease, which is an important cause of morbidity and mortality in these patients and the most common morbidity found in this study was left ventricular hypertrophy.Keywords
Chronic Kidney Disease, Cardiovascular Complications, Echocardiography.References
- Jardine AG, McLaughlin K. Cardiovascular complications of renal disease. Heart 2001;86:459–466.
- Nolan CR. Strategies for improving long-term survival in patients with ESRD. J Am Soc Nephrol 2005;16:S120–S127.
- Foley RN1, Parfrey PS, Harnett JD, Kent GM, Martin CJ, Murray DC et al. Clinical and echocardiographic disease in patients starting end-stage renal disease therapy. Kidney Int 1995 Jan;47(1):186-92.
- Ulasi LL, Arodiwe EB, Ijoma CK.Left ventricular hypertrophy in African Black patients with chronic renal failure at first evaluation. Ethn Dis 2006 Autumn; 16(4):859-64.
- Levin Adeera. Clinical epidemiology of cardiovascular disease in chronic kidney disease prior to dialysis. Semin Dial 2003 Mar-Apr;16(2):101-5
- Stewart GA, Gansevoort RT, Mark PB, Rooney E, McDonagh TA, Dargie HJ et al. Electrocardiographic abnormalities and uremic cardiomyopathy. Kidney Int 2005 Jan;67(1):217-26.
- Costa Fde A, Rivera IR, Vasconcelos ML, Costa AF, Povoa RM, Bombig MT et al. Electrocardiography in the diagnosis of ventricular hypertrophy in patients with chronic renal disease.[Article in English, Portuguese, Spanish]. Arq Bras Cardiol 2009 Oct;93(4):380-6.
- Shapira OM1, Bar-Khayim Y. ECG changes and cardiac arrhythmias in chronic renal failure patients on hemodialysis. J Electrocardiol 1992 Oct;25(4):273-9.
- Chinwuba Ijoma, Ejikeme Arodiwe, Ifeoma Ulasi, Benedict Anisiuba. Pericardial Thickening is a Major Cardiac Complication in Patients with Chronic Kidney Disease at First Presentation. International Journal of Nephrology & Urology 2010;2(3):438-446.
- Kamalesh M, Campbell S, Chong CK, Gipson A, Patel N, Ng C et al. Metabolic syndrome attenuates effect of chronic kidney disease on prevalence of coronary disease in men referred for stress imaging study. Clin Nephrol 2009 Mar;71(3):255-62.
- de Lusignan, Chan T, Stevens P, O’Donoghue D, Hague N, Dzregah B, et al. Identifying patients with chronic kidney disease from general practice computer records. Fam Pract 2005;22(3):234–241.
- Takenori Otsuka, Makoto Suzuki, Hisao Yoshikawa, Kaoru Sugi. Ventricular diastolic dysfunction in the early stage of chronic kidney disease. Journal of Cardiology 2009;54(2):199–204.
- Parfrey PS,Foley RN, Harnett JD, Kent GM, Murray DC, Barre PE. Outcome and risk factors for left ventricular disorders in chronic uremia. Nephrol Dial Transplant 1996 Jul;11(7):1277-85.
- Mercury Poisoning with Acute Kidney Injury
Abstract Views :441 |
PDF Views:93
Authors
Affiliations
1 Dept. of Nephrology, Gauhati Medical College and Hospital, IN
2 Gauhati Medical College and Hospital, Guwahati, Assam, IN
1 Dept. of Nephrology, Gauhati Medical College and Hospital, IN
2 Gauhati Medical College and Hospital, Guwahati, Assam, IN
Source
International Journal of Health Research and Medico Legal Practice, Vol 4, No 1 (2018), Pagination: 102-104Abstract
Exposure to inorganic mercury or mercuric salt can occur as an occupational hazard or suicidal attempt and can cause vomiting, severe abdominal pain, gastrointestinal bleeding, hypovolemic shock and renal tubular necrosis leading to oliguria or anuria. Hemodialysis is used in severe cases of toxicity when renal function has declined. This report aims at highlighting the clinical presentation and course of a case of mercuric poisoning who was treated with hemodialysis. This article reports a case of mercury poisoning whose renal failure improved with high flux hemodialysis. A 25 years old girl ingested a heavy metal compound containing Mercuric chloride obtained from her place of work in a deliberate suicidal attempt, following which she developed massive hematemesis, hypotension and developed renal failure with anuria. She was treated with broad spectrum antibiotics, IV pantoprazole and high flux hemodialysis. Renal biopsy was suggestive of acute tubular necrosis. After 7 hemodialysis her urine output began to improve and dialysis was stopped. Her renal function gradually improved and her blood mercury level also decreased. We have here by presented a case of mercury intoxication with acute tubular necrosis in a 25-year old woman, with an excellent improvement of the renal failure and normalization of laboratory results with high flux hemodialysis.Keywords
High Flux Dialysis, Renal Biopsy, Acute Tubular Necrosis.References
- Barnes JL, McDowell EM, McNeil JS, Flamenbaum W, Trump BF. Studies on the pathophysiology of acute renal failure veffect of chronic saline loading on the progression of proximal tubular injury and functional impairment following administration of mercuric chloride in the rat. Virchows Arch B Cell Pathol InclMol Pathol 1980;32(3):233-60.
- Norseth T, Clarkson TW.Intestinal transport of 203hg-labelled methyl mercury chloride role of biotransformation in rats. Archives of Environmental Health 1971;22(5):568–77.
- Kostial K, Kello D, Jugo S, Rabar I, Maljkoviæ T. Influence of age on metal metabolism and toxicity. Environ Health Perspect 1978 Aug;25:81–6.
- Taugner R, Winkel KZum, Iravani J. The localization of mercuric chloride concentration in the rat kidney. Virchows Archiv 1966;340(4):369–83.
- Cherian MG, Clarkson TW. Radioactive mercury distribution in biological fluids and excretion in human subjects after inhalation of mercury vapour. Archives of Environmental Health 1978;33(3):109–14.
- Berlin M, Ullberg S. Accumulation and retention of mercury in the mouse i an autoradiography study after a single intravenous injection of mercuric chloride. Archives of Environmental Health 1963;(6):589–601.
- Bjornberg KA, Vahter M, Berglund B. Transport of methyl mercury and inorganic mercury to the fetus and breast-fed infant. Environ Health Perspect 2005;113:1381–5.
- Dargan PI, Giles LJ, Wallace CI, House IM, Thomson AH, Beale RJ, et al. Severe mercuric sulphate poisoning treated with 2,3-dimercaptopropane-1-sulphonate and haemodiafiltration. Crit Care 2003;7:1–6.
- Yoshida M, Satoh H, Igarashi M, Akashi K, Yamamura Y, Yoshida K. Acute mercury poisoning by intentional ingestion of mercuric chloride. Tohoku J ExpMed 1997;182:347–52.
- Rothstein A, Hayes AD. The metabolism of mercury in the rat studied by isotope techniques. J PharmacolExpTher 1960;130:166.