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Authors
Affiliations
1 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), New Delhi, 110 062, IN
Source
Scientia Pharmaceutica, Vol 70, No 3 (2002), Pagination: 277-286
Abstract
Various amide-based prodrugs of sulphonamides have been synthesised by condensing appropriate sulphonamide moiety with different β-aroyl propionic acids. All the compounds have been evaluated for their antimicrobial and anti-inflammatory activities. Their structures were established on the basis of elemental analysis, 1H NMR and Mass spectral data. Some of these compounds were found to have significant activity.
Keywords
Sulphonamides, Prodrugs, Amides, Anti-Inflammatory, Antimicrobial
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