Informatics Publishing Limited

Deepak Nallaswamy Veeraiyan ¹, Lakshminarayanan Arivarasu ², Anitha Roy ², S. Rajeshkumar ², Lakshmi Thangavelu ², Devaraj Ezhilarasan ², M. Subha ³

Affiliations
1 Professor, Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Tamil Nadu, IN
2 Associate Professor, Department of Pharmacology, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Tamil Nadu, IN
3 Associate Professor, Department of Oral Medicine & Radiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Tamil Nadu, IN

Abstract

Aim: To prepare and evaluate the antibacterial activity of Coconut oil-mediated effervescent denture cleansing granules.

Materials and Method: The components such as citric acid, tartaric acid and sodium bicarbonate were taken in a ratio of 1: 2: 3 to prepare the effervescent granules by dry method. The citric acid crystals were powered first and then mixed with tartaric acid. Coconut oil was mixed with sodium bicarbonate initially. Both the powders were mixed using geometric dilution, further sieved and packed in air tight containers. Different concentrations of the prepared Coconut oil effervescent denture cleansing solution was tested against Streptococcus mutans and Enterococcus faecalis and Candida albicans in their respective medium and the zone of inhibition was recorded after incubation overnight at 37° c.

Result: The effervescent granules prepared using Coconut oil showed good dose dependent antimicrobial activity against the tested microorganism such as Streptococcus mutans, Enterococcus faecalis and Candida albicans.

Conclusion: The effervescent denture cleansing granules prepared with Coconut oil were found to be active against S. mutans, E. faecalis and Candida albicans at higher concentrations. Hence it may be used for routine cleansing of denture to protect the denture users from infections such as denture stomatitis.

Keywords

Coconut Oil, Effervescent Granules, Denture Cleanser, Denture Stomatitis.

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