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Sravanthi, K.
- Evaluation of Anti-inflammatory and Analgesic potency of Whole Plant Extract of Solanum surattense in Experimental Animals
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Authors
Affiliations
1 Department of Pharmacology, Hindu College of Pharmacy, Guntur, (A.P), IN
2 Department of Pharmacognosy, A. S. N College of Pharmacy, Guntur, (A.P), IN
3 Department of Pharmacology, Calcutta institute of pharmaceutical t A.H.S, Kolkata, IN
1 Department of Pharmacology, Hindu College of Pharmacy, Guntur, (A.P), IN
2 Department of Pharmacognosy, A. S. N College of Pharmacy, Guntur, (A.P), IN
3 Department of Pharmacology, Calcutta institute of pharmaceutical t A.H.S, Kolkata, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 5, No 2 (2013), Pagination: 101-105Abstract
The anti-inflammatory effect of the alcoholic extract of Solanum surattense whole plant was assessed in the carrageenan-induced rat paw edema, the antinociceptive effect of the alcoholic extract of Solanum surattense, plant was studied using thermal and chemical-induced pain models using animals, at the doses of 100 and 200 mg/kg body weight. The acute toxicity and the phytochemical constituents of the extract were also determined. The estimated LD50 of the extract was 2gm/kg body weight. Extract significantly (P<0.05), dose-dependently demonstrated anti-inflammatory activity against acute inflammation induced by carrageenan and also the extract significantly (P<0.05) prolonged the pain reaction times in tail flick pain model, and reduced acetic acid-induced writhing. Phytochemical analysis revealed the presence of alkaloids, saponins, flavanoids and carbohydrates in the plant.Keywords
Analgesic, Anti-inflammatory, Carrageenan, Acute Toxicity, Solanum SurattenseReferences
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- Applications of Graph Labeling in Communication Networks
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Authors
Affiliations
1 Department of CSE, Vignan’s Lara Institute of Technology and Science, Guntur - 522 124, IN
2 Vignan’s Lara Institute of Technology and Science, Bapatla Engineering College, Bapatla, Guntur, IN
1 Department of CSE, Vignan’s Lara Institute of Technology and Science, Guntur - 522 124, IN
2 Vignan’s Lara Institute of Technology and Science, Bapatla Engineering College, Bapatla, Guntur, IN