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Ramana, K. V.
- Evaluation of Anti-inflammatory and Analgesic potency of Whole Plant Extract of Solanum surattense in Experimental Animals
Abstract Views :336 |
PDF Views:2
Authors
Affiliations
1 Department of Pharmacology, Hindu College of Pharmacy, Guntur, (A.P), IN
2 Department of Pharmacognosy, A. S. N College of Pharmacy, Guntur, (A.P), IN
3 Department of Pharmacology, Calcutta institute of pharmaceutical t A.H.S, Kolkata, IN
1 Department of Pharmacology, Hindu College of Pharmacy, Guntur, (A.P), IN
2 Department of Pharmacognosy, A. S. N College of Pharmacy, Guntur, (A.P), IN
3 Department of Pharmacology, Calcutta institute of pharmaceutical t A.H.S, Kolkata, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 5, No 2 (2013), Pagination: 101-105Abstract
The anti-inflammatory effect of the alcoholic extract of Solanum surattense whole plant was assessed in the carrageenan-induced rat paw edema, the antinociceptive effect of the alcoholic extract of Solanum surattense, plant was studied using thermal and chemical-induced pain models using animals, at the doses of 100 and 200 mg/kg body weight. The acute toxicity and the phytochemical constituents of the extract were also determined. The estimated LD50 of the extract was 2gm/kg body weight. Extract significantly (P<0.05), dose-dependently demonstrated anti-inflammatory activity against acute inflammation induced by carrageenan and also the extract significantly (P<0.05) prolonged the pain reaction times in tail flick pain model, and reduced acetic acid-induced writhing. Phytochemical analysis revealed the presence of alkaloids, saponins, flavanoids and carbohydrates in the plant.Keywords
Analgesic, Anti-inflammatory, Carrageenan, Acute Toxicity, Solanum Surattense
References
- Tripathi. K.D .Essentials of Medical Pharmacology. 4th Edition, published by Jaypee Brothers, New Delhi, 2002; 612-614.
- Singh N, Kapur KK and Singh SP. Mechanism of cardiovascular action of Terminalia arjuna . J Med Plant Res. 1982; 45:102-104.
- The Ayurvedic Formulary of India, Part-II, 2000, 1st edition, The Controller of Publications, Delhi, p.35.
- Baydar NG, Ozkan G, Sagdic O. Total phenolic contents and antibacterial activities of grape (Vitis vinifera L.) extracts. Food Control 2004; 15:335-339.
- Akoh CC, Bonilla EP, Sellappan S, Krewer G. Phenolic content and antioxidant capacity of Muscadine grapes. Journal of Agricultural and Food Chemistry 2003; 51:5497-5503.
- Frankel EN, Kanner J, German JB, Parks E, Kinsella JE. Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine. The Lancet 1993; 341(20):454- 457.
- Mayer AS, Yi OS, Person DA, Waterhouse DL, Frankel EN. Inhibition of human low density lipoprotein oxidation in relation to composition of phenolic antioxidants in grapes (Vitis vinifera). Journal of Agricultural and Food Chemistry 1997; 45:1638-1643.
- Teissedre PL, Frankel EN, Waterhouse AL, Peleg H, German GB. Inhibition of in vitro human LDL oxidation by phenolic antioxidants from grapes and wines. Journal of the Science of Food and Agriculture 1996; 70:55-61.
- Waterhouse AL. Wine antioxidants may reduce heart disease and cancer. Presentation of American Chemical Society, Washington; 1994.
- Renaud S, Lorgeril MD. Wine, alcohol, platelets and the French paradox for coronary heart disease. The Lancet 1992; 339:1523- 1526.
- Davalos A, Bortolome B, Gomez-cordoves C. Antioxidant properties of commercial grape juices and vinegars. Food Chemistry 2005; 93(2):325-330.
- Orhan DD, Orhan N, Ergun E, Ergun F. Hepatoprotective effect of Vitis vinifera L. leaves on carbon tetrachloride-induced acute liver damage in rats. Jornal of Ethnopharmacology 2007; 112:145-151.
- Corder R, Mullen W, Khan NQ, Marks SC, Wood EG, Carrier MJ, Crozier A. Red wine procyanidins and vascular health. Nature 2006;444:566.
- Mishra S. Bhaisazya Kalpana Vigyan. Varanasi, India: Chaukambha Surbharati Prakashan; 2005.p. 253-254.
- Alam M, Radhamani S, Ali U, Purushottam KK. Microbiological Screening of Dhataki Flowers. Journal of Research in Ayurveda and Siddha 1984; 2(4):371-375.
- Braugghler JM, Duncan CA and Chase IR. The involvement of iron in lipid peroxidation. J Biol Chem. 1986; 261(22): 10282- 89.
- Lowery OH, Rosenbrough NJ, Farr AL and Randall RJ. Protein estimation with Folin phenol reagent. Biol Chem. 1951;193:265-275.
- Khanna AK, Chander R and Kapoor NK. Terminala arjuna: an Ayurvedic cardiotonic, Regulates lipid metabolism in Hyperlipidemic rats. Phytother Res. 1996;10: 663-665.
- Allain CC, Poon LS, Chan CS and Richmond W. Enzymatic Determination of Total Serum cholesterol. Clin Chem .1974;20::447-475.
- Friedewald WT, Levy RI and Fredrickson DS. Estimation of concentration of low density cholesterol in plasma without use of ultracentrifuge. J Clin Chem .1972;18: 449-502.
- Muller PH, Schmulling RM, Liebich HM and Eggstein M. A fully Enzymatic Triglyceride Determination. J Clin Chem. 1977;15:457-464.
- Anne SM, Ock SY, Debra AP, Andrew LW and Edwin NF. Inhibition of Human Low Density Lipoprotein oxidation in relation to composition of Phenolic antioxidants in Grapes (Vitis Vinifera). J Agri Food Chem. 1997;45 (5):1638-1643.
- S Renaud, and M De Lorgeril. Wine, alcohol, Platelets and the French Paradox for Coronary Heart Disease. The Lancet. 1992; 339: 1523-1526.
- Pederson TR. Low- density lipoprotein cholesterol lowering is and will be the key to the future of lipid management. American J Cardiol. 2001; 87(5A): 8B-12B.
- Boden WE and Pearson TA. Raising low levels of High Density Lipoprotein Cholesterol is an important target of therapy. American J cardiol. 2000; 85(5):645-650.
- Analysis of MR Damper for Quarter and Half Car Suspension Systems of a Roadway Vehicle
Abstract Views :432 |
PDF Views:268
Authors
Affiliations
1 Dept.of Mech. Engg., K L University, Vaddeswaram, Guntur, IN
2 Dept.of Mech. Engg., University College of Engg., JNTUK, Kakinada, Andhra Pradesh, IN
1 Dept.of Mech. Engg., K L University, Vaddeswaram, Guntur, IN
2 Dept.of Mech. Engg., University College of Engg., JNTUK, Kakinada, Andhra Pradesh, IN
Source
International Journal of Vehicle Structures and Systems, Vol 9, No 1 (2017), Pagination:Abstract
Magnetorheological (MR) dampers are evolving as one of the most promising devices for semi-active vibration control of various dynamic systems. In this paper, the suspension system of a car using MR damper is analysed for 2DOF quarter car and 4DOF half car models and then compared with corresponding suspension system using passive damper for ride comfort and handling. Magnetorheological damper is fabricated using a MR fluid of Carbonyl iron powder and Silicone oil added with additive. Experiments are conducted to establish the behaviour of the MR damper and are used to validate Spencer model for MR damper. Further, using the validated Spencer model of MR damper, the quarter car and half car models of Vehicle Suspension system are simulated by implementing a semi-active suspension system for analysing the resulting displacement and acceleration in the car body. The ride comfort and vehicle handling performance of each specific vehicle model with passive suspension system are compared with corresponding semi-active suspension system. The simulation and analysis are carried out using MATLAB/SIMULINK.Keywords
Magnetorheological Dampers, Suspension Systems, Spencer Model, Simulation and Fabrication of MR Damper.Full Text
References
- D. Ryba. 1974. Improvements in dynamic characteristics of automobile suspension systems part 1. two-mass systems, Vehicle System Dynamics, 3(1). https://doi.org/ 10.1080/00423117408968445.
- D.A. Crolla and M.B.A. Abdel-Hady. 1991. Active suspension control performance comparisons using control laws applied to a full-vehicle model, Vehicle System Dynamics, 20(2), 107-120. http://dx.doi.org/ 10.1080/00423119108968982.
- J Wang and G Meng. 2001. Magnetorheological fluid devices principles, characteristics and applications in mechanical engg., Proc. IMechE Part J. Materials: Design & Applications, 3, 165-174.
- R. Turczyn and M. Kciuk. 2008. Preparation and study of model Magnetorheological fluids, J. Achievements in Materials and Manufacturing Engg., 27(2), 131-134.
- M. Jolly, J.W. Bender and J.D. Carlson. 1998. Properties and applications of commercial magnetorheological fluids, Proc. SPIE 5th Annual Int. Symp. Smart Structures and Materials, San Diego, USA.
- B.F. Spencer, S. Dyke, M. Sain and J. Carlson. 1997. Phenomenological model for magnetorheological dampers, J. Eng. Mech., 123(3), 230-238. http://dx.doi.org/10.1061/(ASCE)0733-9399(1997)123 :3(230).
- V.K. Grag and R.V. Dukkipati. 1984. Dynamics of Railway Vehicle Systems, Academic Press Inc.
- B. Sapiński and J. Filuś. 2003. Analysis of parametric models of MR linear damper. J. Theoretical and Applied Mechanics, 41(2), 215-240.
- Measurement of Surface Roughness of Machined Surfaces Using Vision Systems
Abstract Views :197 |
PDF Views:0
Authors
Affiliations
1 Dept. of Industrial & Production Engg., Koneru Lakshmaiah College of Engineering, Vaddeswaram, P.O. Guntur Dt-522502, IN
1 Dept. of Industrial & Production Engg., Koneru Lakshmaiah College of Engineering, Vaddeswaram, P.O. Guntur Dt-522502, IN
Source
Manufacturing Technology Today, Vol 5, No 11 (2006), Pagination: 5-8Abstract
With the increasing demand for accurate engineering products, the control of surface texture has become vital. Surface roughness of machined parts need to be specified on the basis of their use and application environment. The geometrical and material properties of surface can significantly affect the friction, wear, fatigue and corrosion of that part. Hence evaluation of surface roughness and characterization of that surface has become essential for design, manufacturing and inspection. Many methods of measuring surface finish have been investigated ranging from simple touch comparator to sophisticated optical techniques. The latest technology of measuring surface roughness is the combination of optical techniques and computer vision systems. In this paper an attempt has been made to develop an experimental technique to measure the surface roughness based on the analysis of the intensity distribution of scattered light from the surface. For this purpose a low cost vision system is proposed. By impinging a laser beam at an angle on the machined surface, a random pattern of bright and dark regions known as speckle is observed. These speckle images are captured using charge coupled device (CCD) camera and are stored in digital format. Further a source code In C++ is developed to read the image data and to compute optical roughness values from stored images. Since the results obtained through this technique are encouraging, this method is well adapted for measurement of rough surface that fall within the range of engineering surface generated by common machining process like grinding, turning and milling. A few conclusions are drawn on the effectiveness of adopting the proposed system.- Design, Analysis and Development of Squeeze Film Dampers for High Speed Machines
Abstract Views :208 |
PDF Views:0
Authors
Affiliations
1 Department of Mechanicai Engineering, K.L. College of Engg. Green fieids, Vaddeswaram, Guntur-522501, IN
1 Department of Mechanicai Engineering, K.L. College of Engg. Green fieids, Vaddeswaram, Guntur-522501, IN
Source
Manufacturing Technology Today, Vol 5, No 1 (2006), Pagination: 7-11Abstract
Present day state of the art in the design of turbo machines has given much scope to the flexible rotor bearing system. The most recurring problem in rotor dynamics is the excessive steady state synchronous vibration levels. Squeeze film dampers (SFD) are the essential components of high-speed turbomachines since they offer the advantage of dissipation of vibration energy and hence prevent rotor dynamic instabilities. A squeeze film damper is used between the bearing and its foundation to reduce the unbalance forces transmitted to the pedestal by introducing an additional damping and there by reduce the amplitude of vibration to acceptable limit. This work highlights the design and development of squeeze film dampers for high-speed machines in a more generic way. The first phase of the work involves the study of the effect of SFD on rotor dynamics based on the parameters like, damping ratio, logarithmic decrement and Transmissibility. A theoretical model Is generated incorporating the said parameters. The dynamic analysis, which is of two fold. Is carried out using ARMD software. The rotor dynamic effects are found without SFD and with SFD. The second phase of the work deals with experimental investigation on a journal-bearing test rig with SFD supports up to a speed of 1800 rpm. At the end, the vibrations obtained through theoretical analysis and experimental investigations are tabulated. It Is concluded that vibration levels are reduced using SFD for the specified optimum inputs.- Evaluation of Human Exposure to Vibrations using Quarter Car Model with Semi-Active Suspension
Abstract Views :330 |
PDF Views:150
Authors
D. V. A. Rama Sastry
1,
K. V. Ramana
2,
N. Mohan Rao
3,
M. Phani Kumar
2,
V. S. S. Rama Chandra Reddy
2
Affiliations
1 Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur, Andhra Pradesh, IN
2 Dept. of Mech. Engg., Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur, Andhra Pradesh, IN
3 Dept. of Mech. Engg., University College of Engg., JNTUK University, Kakinada, Andhra Pradesh, IN
1 Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur, Andhra Pradesh, IN
2 Dept. of Mech. Engg., Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur, Andhra Pradesh, IN
3 Dept. of Mech. Engg., University College of Engg., JNTUK University, Kakinada, Andhra Pradesh, IN
Source
International Journal of Vehicle Structures and Systems, Vol 10, No 4 (2018), Pagination: 268-272Abstract
Exposure of human body to vehicular vibrations in transit may lead to the human discomfort. Ride comfort is one of the major issues in design of automobiles. Magneto rheological (MR) dampers are emerging as most feasible solution for various applications in controlling vibrations. An MR damper is a semi-active device, which will offer the advantages of both active and passive suspension. In this study, the MR damper based semi-active suspension system for a car is analysed for ride comfort of 7 degrees of freedom model human body lumped mass, considering head, upper torso, lower torso and pelvis, seated over a seat of a quarter car model and is compared with that of similar system using passive damper. A MR damper is fabricated and is filled with MR fluid made of Carbonyl iron powder and Silicone oil added with additive. Modified Bouc-Wen Model developed by Spencer is used to model the behaviour of MR damper. All the parameters of this model are identified using data acquired from experiments conducted to characterise MR damper. Further, using the Spencer model of MR damper, the human body seated over quarter car is simulated by implementing a semi-active suspension system for analysing the resulting displacement and acceleration of the human body. The ride comfort performance of vehicle model with passive suspension system is compared with corresponding semi-active suspension system. The simulation and analysis are carried out using MATLAB/SIMULINK.Keywords
Magneto Rheological Dampers, Quarter Car Model, Suspension Systems, Spencer Model, Human Body Vibrations.Full Text
References
- D. Ryba. 1974. Improvements in dynamic characteristics of automobile suspension systems: Part 1 - Two-mass systems, Vehicle System Dynamics, 3(1), 17-46. https://doi.org/10.1080/00423117408968445.
- R. Rajalakshmi, S.R. Kumar, J. Thiyagarajan and A. Vinothkumar. 2017. Evaluation of human exposure to vibration subjected to active suspension actuators, Int. J. Vehicle Structures & Systems, 9(2), 68-71. https://doi.org/10.4273/ijvss.9.2.01.
- J. Wang and G. Meng. 2001. Magneto rheological fluid devices: principles, characteristics and applications in mechanical engineering, Proc. IMechE J. Materials: Design & Applications, 215(3), 165-174.
- R. Turczyn and M. Kciuk. 2008. Preparation and study of model Magneto rheological fluids, J. Achievements in Materials and Manuf. Engg., 27(2), 131-134.
- M. Jolly, J.W. Bender and J.D. Carlson. 1998. Properties and applications of commercial magneto rheological fluids, Proc. SPIE 5th Annual Int. Symposium Smart Structures and Materials, San Diego.
- B.F. Spencer, S. Dyke, M. Sain, and J. Carlson. 1997. Phenomenological model for magneto rheological dampers, ASCE J. Engg. Mech., 1-23.
- V.K. Grag and R.V. Dukkipati. 1984. Dynamics of Railway Vehicle Systems, Academic Press Inc.
- B. Sapiński and J. Filus. 2003. Analysis of parametric models of MR linear damper, J. Theoretical and Applied Mechanics, 41(2), 215-240.
- Analysis and Prediction of Performance of MR Damper at Different Currents and Control Strategies for Quarter Suspension System of a Roadway Vehicle
Abstract Views :674 |
PDF Views:196
Authors
Affiliations
1 Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur, Andhra Pradesh, IN
2 University College of Engg., JNTUK University, Kakinada, Andhra Pradesh, IN
1 Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur, Andhra Pradesh, IN
2 University College of Engg., JNTUK University, Kakinada, Andhra Pradesh, IN
Source
International Journal of Vehicle Structures and Systems, Vol 11, No 1 (2019), Pagination: 27-32Abstract
Ride comfort and vehicle handling are the two major issues to be dealt in the design of suspension systems of automobiles. With passive systems offering contrariety on these two parameters, the alternative systems are being in study. Magnetorheological (MR) damper, a most feasible semi-active device, is one such alternative, which will offer the advantage of dealing with both these issues overcoming contrariety. In this study, the suspension system of a car using MR damper is analysed at 5 different currents viz., 0A, 0.25A, 0.5A, 0.75A, 1A, using 2DOF quarter car model and 4DOF half car models for ride comfort and handling and the comparisons of these are done with same suspension system equipped with regular passive damper. A MR damper is built-up using MR fluid consisting of carbonyl iron powder and silicone oil added with additive. Further, the characteristic of this damper is established by conducting experiments, which in turn is used to identify the parameters of Spencer model for MR damper. Using Spencer model of MR damper, at 5 different currents, the quarter car and half car models of vehicle suspension system are simulated by implementing a semi-active suspension system for analysing the resulting displacement and acceleration in the car body. The ride comfort and vehicle handling performance of each specific vehicle model with passive suspension system are compared with corresponding skyhook, ground hook and hybrid based semi-active suspension systems. The simulation and analysis are carried out using Matlab/Simulink.Keywords
Magnetorheological Dampers, Semi Active Suspension Systems, Spencer Model, Skyhook, Ground Hook Hybrid Control.Full Text
References
- D. Ryba. 1974. Improvements in dynamic characteristics of automobile suspension systems part 1. Two-mass systems, Vehicle System Dynamics, 3(1), 17-46. https://doi.org/10.1080/00423117408968445.
- R. Rajalakshmi, S. Rajeshkumar, J. Thiyagarajan, A. Vinothkumar. 2017. Evaluation of human exposure to vibration subjected to active suspension actuators, Int. J. Vehicle Structures & Systems, 9(2), 68-71. https://doi.org/10.4273/ijvss.9.2.01.
- J. Wang and G. Meng. 2001. Magnetorheological fluid devices: principles, characteristics and applications in mechanical engineering, IMAHE, J. Materials: Design & Applications, Part L, 215(3), 165-174. https://doi.org/10.1243/1464420011545012.
- R. Turczyn and M. Kciuk. 2008. Preparation and study of model magnetorheological fluids, J. Achievements in Materials and Manuf. Engg., 27(2), 131-134.
- M. Jolly, J.W. Bender and J.D. Carlson. 1998. Properties and applications of commercial magnetorheological fluids, Proc. SPIE 5th Annual Int. Symp. Smart Structures and Materials, San Diego.
- Jr.B.F. Spencer, S. Dyke, M. Sain and J. Carlson. 1997. Phenomenological model for magnetorheological dampers, J. Engg. Mech., 1-23.
- D.V.A.R. Sastry, K.V. Ramana, N.M. Rao, P. Pruthvi and D.U.V. Santhosh. 2016. Analysis of MR damper for quarter and half car suspension systems of a roadway vehicle, Int. J. Vehicle Structures & Systems, 9(1), 17-22.http://dx.doi.org/10.4273/ijvss.9.1.04.
- V.K. Grag and R.V. Dukkipati. 1984.Dynamics of Railway Vehicle Systems, Academic Press Inc.
- D. Karnopp, J. Crosby and R. Harwood. 1973. Vibration Control using Semi-Active Force Generators, Lord Library of Technical Articles, LL-7004.
- S.B. Choi, W. Li, M. Yu, H. Du, J. Fu and P.X. Do. 2016. State of the art of control schemes for smart systems featuring magneto-rheological materials, Smart Mater. Struct., 25. https://doi.org/10.1088/0964-1726/25/4/043001.
- S.M. Savaresi and C. Spelta. 2007. Mixed sky-hook and approaching the filtering limits of a semi-active suspension,J. Dyn. Syst. Meas. Control, 129, 382-392. https://doi.org/10.1115/1.2745846.