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Dahiya, Jyoti
- Spectrophotometric Estimation of Dextromethorphan in Bulk Drug using Hydrotropic Solubilization Technique
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Authors
Affiliations
1 College of Pharmacy, Shree Ganpati Institute of Technology, NH-24, Opp. Jindal Pipes Ltd, Ghaziabad, (U.P.), IN
1 College of Pharmacy, Shree Ganpati Institute of Technology, NH-24, Opp. Jindal Pipes Ltd, Ghaziabad, (U.P.), IN
Source
Asian Journal of Pharmaceutical Analysis, Vol 3, No 3 (2013), Pagination: 90-93Abstract
A simple, rapid and precise spectrophotometric method has been developed for determining the enhancement in the aqueous solubility Dextromethorphan. Method is based on the absorbance. Dextromethorphan maximum is found at 278nm with hydrotrope dextromethorphan in double distilled water as solvent. The linearity was obtained in the concentration range of 10-120μg/ml with coefficient of correlation 0.9993.The % RSD in case of intra-day and inter day was found to be 0.8182 and 0.9438 respectively. The value of LOD and LOQ was found to be 3.76 and 1.141 respectively. The method is found to be accurate, precise and useful in quality control of API Drug and also to enhance the aqueous solubility of Dextromethorphan.Keywords
Dextromethorphan, Hydrotropic Study, Enhancement of Solubility, Method Development and ValidationReferences
- Li P Zhao L, Developing early formulations: Practice and perspective. International Journal of Pharmaceutics 341(1-2); 2007:1-19.
- C. Neuberg, Biochem Z., 1916, 76: 107.
- Cui Y Parallel stacking of caffeine with riboflavin in aqueous solutions: The potential mechanism for hydrotropic solubilization of riboflavin. International Journal of Pharmaceutics 15 397(1-2); 2010:36-43.
- Jain N Jain R Jain A Pandey SP Jain DK Spectrophotometric quantitative estimation of amlodipine besylate in bulk drug and their dosage forms by using hydrotropic agent. Eurasian J. Anal. Chem. 5; 2010: 212-217.
- Pandey S Maheshwari RK A novel Spectroscopic Method for the estimation of Ketoprofen in tablet dosage form using hydrotropic solubilization phenomenon. World Applied Sciences Journal 11; 2010:1524 - 1527.
- Maheshwari RK Indurkhya A Novel application of mixed hydrotropic solubilization technique in the formulation and evaluation of hydrotropic solid dispersion of aceclofenac. Asian Journal of Pharmaceutics 4; 2010: 235 - 238.
- Vemula VR Lagishetty V Lingala S Solubility enhancement techniques. Int. J. Pharm. Sci., Review and Research 5 (1); 2010: 41-51.
- Saravanakumar G Choi KY Yoon HY Kim K Park JH Kwon IC Park K Hydrotropic hyaluronic acid conjugates: Synthesis, characterization, and implications as a carrier of paclitaxel. International Journal of Pharmaceutics 394; 2010: 154-161.
- Baghel US Dhiman V. Exploring the Application of Hydrotropic Solubilization Phenomenon for Estimating Diacerein in Capsule Dosage Form by Spectrophotometry Methods. Asian Pacific Journal of Tropical Biomedicine. 2010: S1720-S1727.
- Maheshwari RK, Lakkadwala S, Vyas R, Ghode P. Spectrophotometric determination of naproxen tablets using niacinamide as hydrotropic solubilizing additive. Journal of Current Pharmaceutical Research4; 2010: 11-14.
- Maheshwari RK Bishnoi SR Kumar D Murali K. Digest Journal of Nanomaterials and Biostructures.5; 2010:97-100.
- Maheswari RK Chandrawashi H, Gupta N, Quantitative estimation of aspirin in tablets and bulk sample using metformin hydrochloride as hydrotropic agent. International Journal of Pharmacy and Pharmaceutical Sciences 2010, 2, 21-23.
- Maheshwari RK Archana A, Amit R, Megha A. Ecofriendly spectrophotometric estimation of atenolol tablets using metformin hydrochloride as hydrotropic solubilizing agent. Journal of Global Pharma Technology. 2; 2010: 93-96
- Jayakumar C, Kumar DK, Nesakumar D, Gandhi NN. Quantitative analysis of theophylline bulk sample using sodium salicylate hydrotrope. International Journal of Pharmacy and Pharmaceutical Sciences 2; 2010:124-125.
- Sherje AP, Anand R, Sriram W, Vanshiv SD. Mixed hydrotropy in spectrophotometric analysis of nitazoxanide. International Journal of Chem. Tech. Research 2; 2010: 1966-1969.
- Maheshwari RK, Rajput MS, Sinha S. New quantitative estimation of benzoic acid bulk sample using calcium disodium edetate as hydrotropic solubilizing agent. Asian Journal of Pharmaceutical and Clinical Research 3; 2010: 43-45.
- Sharma MC, Sharma S. Spectrophotometric determination of Lamivudine in Bulk and Pharmaceutical Formulation using hydrotropic Solubilization. Int. J. Pharm Tech Research3; 2011:988-991.
- Fabregas JL, Margalet A. GLC trace analysis of Dextromethorphan and bromhexine salts in pharmaceutical preparations. Journal of Pharmaceutical Sciences. 64(6); 1975: 1005-1006
- International Conference on Harmonization, (2005) Guidance for Industry in: Q2B Validation on Analytical Procedures. Methodology Switzerland IFPMA, 1.
- Pharmacognostical and Phytochemical Studies of Leaves of Plectranthus Amboinicus (Lour.) Spreng. (Parnayavani)
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Authors
Dipsundar Sahu
1,
Rajesh Bolleddu
2,
Manosi Das
3,
Debajyoti Das
1,
Tusar Kanti Mandal
1,
Saroj Kumar Debnath
1,
Laxmidhar Barik
1,
Jyoti Dahiya
4,
Suvendu Mandal
5,
P V V Prasad
6
Affiliations
1 Research Officer (Ayurveda), Central Ayurveda Research Institute, Kolkata, West Bengal, India, Central Council for Research in Ayurvedic Sciences, Ministry of AYUSH, Government of India., IN
2 Research Officer (Pharmacognosy), Central Ayurveda Research Institute, Kolkata, West Bengal, India, Central Council for Research in Ayurvedic Sciences, Ministry of AYUSH, Government of India., IN
3 Research Officer (Chemistry), Central Ayurveda Research Institute, Kolkata, West Bengal, India, Central Council for Research in Ayurvedic Sciences, Ministry of AYUSH, Government of India., IN
4 Assistant Research Officer (Pharmacognosy), Central Ayurveda Research Institute, Kolkata, West Bengal, India, Central Council for Research in Ayurvedic Sciences, Ministry of AYUSH, Government of India., IN
5 Senior Research Fellow (Chemistry), Central Ayurveda Research Institute, Kolkata, West Bengal, India, Central Council for Research in Ayurvedic Sciences, Ministry of AYUSH, Government of India., IN
6 Director (Institute), Central Ayurveda Research Institute, Kolkata, West Bengal, India, Central Council for Research in Ayurvedic Sciences, Ministry of AYUSH, Government of India., IN
1 Research Officer (Ayurveda), Central Ayurveda Research Institute, Kolkata, West Bengal, India, Central Council for Research in Ayurvedic Sciences, Ministry of AYUSH, Government of India., IN
2 Research Officer (Pharmacognosy), Central Ayurveda Research Institute, Kolkata, West Bengal, India, Central Council for Research in Ayurvedic Sciences, Ministry of AYUSH, Government of India., IN
3 Research Officer (Chemistry), Central Ayurveda Research Institute, Kolkata, West Bengal, India, Central Council for Research in Ayurvedic Sciences, Ministry of AYUSH, Government of India., IN
4 Assistant Research Officer (Pharmacognosy), Central Ayurveda Research Institute, Kolkata, West Bengal, India, Central Council for Research in Ayurvedic Sciences, Ministry of AYUSH, Government of India., IN
5 Senior Research Fellow (Chemistry), Central Ayurveda Research Institute, Kolkata, West Bengal, India, Central Council for Research in Ayurvedic Sciences, Ministry of AYUSH, Government of India., IN
6 Director (Institute), Central Ayurveda Research Institute, Kolkata, West Bengal, India, Central Council for Research in Ayurvedic Sciences, Ministry of AYUSH, Government of India., IN
Source
Research Journal of Pharmacy and Technology, Vol 15, No 2 (2022), Pagination: 717-722Abstract
Plectranthus amboinicus (Lour.) Spreng. (family Lamiaceae) is commonly known as parnayavani by the several ethnic groups of West Bengal. The plant used by the traditional healers in cough, common cold, abdominal flatulence, indigestion, constipation etc. The preliminary phytochemical analysis, HPTLC finger printing and detailed pharmacognostical studies of its leaves revealed presence of distinctive characteristics, which help in identifying the specimen.Keywords
Plectranthus amboinicus, Pharmacognosy, Phytochemistry, HPTLC, Parnayavani.References
- C. W. Lukhoba, M. S. J. Simmonds, and A. J. Paton. Plectranthus a review of ethnobotanical uses. Journal of Ethnopharmacology. 2006; 103(1): 1–24.
- C. W. Lukhoba, M. S. J. Simmonds, and A. J. Paton. Plectranthus: a review of ethnobotanical uses. Journal of Ethnopharmacology. 2006; 103(1):1–24.
- A. Senthilkumar and V. Venkatesalu. Chemical composition and larvicidal activity of the essential oil of Plectranthus amboinicus (Lour.) Spreng against Anopheles stephensi: a malarial vector mosquito. Parasitology Research. 2010; 107(5): 1275–1278.
- Warier PK and Nambier VP. Indian Medicinal Plants: A compendium of 500 species. Vol.4. Orient Longman Limited, Chennai; 1996. p. 315.
- Nadkarni AK. Indian Materia Medica. Vol.1. 3rd ed. Popular Prakashan, Bombay, India; 2002. p. 371-72.
- Prajapati ND, Purohit SS, Sharma AK, Kumar T. A Handbook of Medicinal Plants Section-II: Medicinal Plants A to Z. India: Agribios; 2003.
- Senthil K (2009) http://landscapingchennai.com/coleus-aromaticus/
- Anonymous. The Wealth of India: A Dictionary of Indian Raw Materials and Industrials Products. Vol.2: Cl-Cy. C.S.I.R. Publications, New Delhi, India; 1998. p. 154.
- Punet Kumar, Sangam, Nitin Kumar. Plectranthus amboinicus: A review on its pharmacological and pharmacognostical studies. A J Physiol Biochem Pharmacol. 2020;10(2).
- Fu L, Fu Z. Plectranthus amboinicus leaf extract– assisted biosynthesis of ZnO nanoparticles and their photocatalytic activity. Ceram Int. 2015; 41(2): 2492–6.
- Herbs-Medicinal plants usage and Identification Data base Country borage (Parnayavani-Plectranthus amboinicus) Medicinal uses Available via https://herbs.indianmedicinalplants.info/index. php/1165-country-borage-parnayavaniplectranthus-amboinicus-medicinal-uses-adverseeffects-research-pharmacology (Accessed 4 March 2020.
- Khandelwal KR. Practical Pharmacognosy Techniques and Experiments. 9th ed. Nirali Prakashan, Pune; 2003.p.320-8.
- Brain KR and Turner TD. The Practical Evaluation of Pharmaceuticals. 2nd ed. Wright Scientechnica Britol;1975.
- Johansen DA. Plant Microtechnique. McGraw Hill Book Co., New York, USA;1940.
- Trease GE and Evans WC. Pharmacognosy. 15th ed. W.B. Saunders Edinburgh London, New York: Philadelphia St. Louis Sydney Toronto; 2002. p. 715-733.
- Wallis TE. Textbook of Pharmacognosy. 6th edition, CBS Publishers and Distributors, New Delhi, 1999. p.578-582.
- Trease GE and Evans WC. Pharmacognosy. W.B. Saunders Edinburgh London, New York: Philadelphia St. Louis Sydney Toronto. 15th ed., 2002.p. 715-733.
- Rungsung W, Dutta S, Mondal DN, Ratha KK, Hazra J. Pharmacognostical Profiling on the Root of Rauwolfia serpentina. International Journal of Pharmacognosy and Phytochemical Research. 2014; 6(3):612-6.
- Anonymous. Quality Control Methods for Herbal Materials (updated edition of Quality Control Methods for Medicinal Plant Materials, 1998). World Health Organization, Geneva, 2011.
- Anonymous. The Ayurvedic Pharmacopoeia of India. Vol. 1, Department of Indian System of Medicine and Homoeopathy, New Delhi, 2001.p.160-161.
- Egon S. Thin-Layer Chromatography-A Laboratory Handbook. 2nd edition. Springer International Edition, 2005.p.52-86.
- ICH guidelines Q2A, Text on Validation of Analytical Procedure, International Conference of Harmonization, Geneva; October. 1994.p.1-5.
- WHO Monographs on Selected Medicinal Plants. World Health Organization, Geneva; 2002.
- Anonymous. Quality control methods forherbal materials (updated edition of qualitycontrol methods for medicinal plant materials,1998). World Health Organization, Geneva; 2011.
- S. Raghavi, V.G. Karthigeyan, S. Prabhu. Protective Effect of Plectranthus amboinicus Leaf Extract Containing Luteolin Flavanoid in Isoproterenol Hydrochloride Induced Myocardial Infarction in Rats - An Assessment on Biochemical and Cellular Changes.
- R Radha, T Sivakumar, S Arokiyaaj. Pharmacognostical Evaluation of Plumeria alba Linn.
- A Rajasekaran, R Arivukkarasu, M Linda. Estimation of Andrographolide Content in Aqueous Extract of Siddha Formulations by HPTLC.
- Kabita Banik, Simhachalam Rath, B K Gupta. Chromatographic Estimation of Niacinamide in Anti aging Dermatological product.
- AK Meena, MM Rao, RP Meena, P Panda, Renu . Pharmacological and Phytochemical Evidences for the Plants of Wedelia Genus– A Review.
- K. P. Jaiganesh, B. Sreedharren, G. Arunachalam, R. Nirmala, R. Nepolean. Pharmacognostical and Antimicrobial investigation of Jatropha curcas, Linn., Leaf.
- Amiza, Ghazala Yaseen, Sammia Shahid. Comprehensive Review on Phytopharmacological Potential of Gymnema sylvestre.
- RB Kakde, VH Kotak, DL Kale . Estimation of Bisoprolol Fumarate in Pharmaceutical Preparations by HPTLC.
- Sachin U Rakesh, VR Salunkhe, PN Dhabale, KB Burade. HPTLC Method for Quantitative Determination of Gallic Acid in Hydroalcoholic Extract of Dried Flowers of Nymphaea Stellata Willd .
- Bhope SG, Kuber VV, Patil MJ, Ghosh VK. Validated HPTLC Method for the Quantitation of Andrographolide from Raw Material and Pharmaceutical Dosage Form .