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Ramesh, J.
- Simultaneous Estimation of Nitazoxanide and Ofloxacin by RP-HPLC Method
Abstract Views :175 |
PDF Views:0
Authors
Affiliations
1 Department of Pharmaceutical Analysis, JKK Munirajah Medical Research Foundation College of Pharmacy, Komarapalayam-638183, Namakkal (DT), Tamilnadu, IN
1 Department of Pharmaceutical Analysis, JKK Munirajah Medical Research Foundation College of Pharmacy, Komarapalayam-638183, Namakkal (DT), Tamilnadu, IN
Source
Asian Journal of Research in Chemistry, Vol 3, No 4 (2010), Pagination: 1062-1064Abstract
The present paper deals with the development of RP-HPLC method for the determination of Nitazoxanide and Ofloxacin in bulk and in formulation using UV detector. Selected mobile phase was a combination of 0.005 M tetra butyl ammonium hydrogen sulphate and acetonitrile in the ratio of 45:55 and the wavelength selected was 240 nm. The flow rate 1.0 ml/min, and the injection volume was 20 μl. The sepration was performed at ambient temperature. Retention time of Nitazoxanide and Ofloxacin was found to be 6.051and 2.106. Linearity of the method was found to be 400 to 600 mcg/ml and 160 to 240 mcg/ml for Nitazoxanide and Ofloxacin respectively. Accuracy of the method was determined through recovery studies by adding known quantities of standard drug to the pre analyzed test solution and was found to be 99.08-99.81% and 100.18-100.65% for Nitazoxanide and Ofloxacin respectively. This method was validated according to ICH guidelines.Keywords
Nitazoxanide, Ofloxacin and RP-HPLC.
- Simultaneous Estimation of Montelukast Sodium and Levocetrizine Hydrochloride by RP-HPLC Method
Abstract Views :177 |
PDF Views:0
Authors
Affiliations
1 Department of Pharmaceutical Analysis, JKK Munirajah Medical Research Foundation College of Pharmacy, Komarapalayam-638183, Namakkal (DT), Tamilnadu, IN
1 Department of Pharmaceutical Analysis, JKK Munirajah Medical Research Foundation College of Pharmacy, Komarapalayam-638183, Namakkal (DT), Tamilnadu, IN
Source
Asian Journal of Research in Chemistry, Vol 3, No 4 (2010), Pagination: 1069-1072Abstract
The present paper deals with the development of RP-HPLC method for the determination of montelukast sodium and levocetrizin hydrochloride in bulk and in formulation using UV detector. Selected mobile phase was a combination of acetonitril, methonal, and water (40:40:20) and the wavelength selected was 232 nm. The flow rate was kept at 1 ml/min, and the injection volume was 20 μl. The separation was performed at ambient temperature. Retention time of montelukast sodium was 11.81 min and for levocetrizine hydrochloride was 6.01 min. Linearity of the method was found to be 0.030 to 0.060 mg/ml for montelukast sodium and 0.030 to 0.060 mg/ml for levocetrizine hydrochloride with the regression coefficient of 0.991 and 0.994 for montelukast sodium and levocetrizine hydrochloride respectively. This method was validated according to ICH guidelines.Keywords
Montelukast, Levocetrizin and RP-HPLC.- Despeckleing Prostate Ultrasonograms Using PDE with Wavelet
Abstract Views :191 |
PDF Views:3
Authors
J. Ramesh
1,
R. Manavalan
2
Affiliations
1 Department of Computer Applications, K.S. Rangasamy College of Arts and Science, IN
2 Department of Computer Science, Arignar Anna Government Arts College, IN
1 Department of Computer Applications, K.S. Rangasamy College of Arts and Science, IN
2 Department of Computer Science, Arignar Anna Government Arts College, IN
Source
ICTACT Journal on Image and Video Processing, Vol 8, No 4 (2018), Pagination: 1776-1780Abstract
Prostate cancer is the leading cause of death for men, since the cause of the disease is mysterious and its early detection is also monotonous. Ultrasound (US) is the most popular tool to detect the human organ glands and also used to diagnose the prostate cancer. Speckle noise is an inherent nature of ultrasound images, which degrades the image quality. So far, No specific filter is available to suppress the speckle noise in prostate image. In this paper, a novel despeckling method PDE with Wavelet is presented for prostate US images. The enhancement method is evaluated by using standard measures like Mean Square Error (MSE), Peak Signal Noise Ratio (PSNR) and Edge Preservation Index (EPI). Further, the despeckling approaches' is also evaluated time and space complexity. From the results, it is observed that the filtering method PDE with Wavelet is superior to PDE in terms of denoising and also preserving the information content.Keywords
Ultrasound Prostate Image, Partial Differential Equation, Wavelet.References
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