Refine your search
Collections
Co-Authors
Year
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Agarwal, Indira
- Acute Kidney Injury Secondary to Rhabdomyolysis
Abstract Views :387 |
PDF Views:0
Authors
Affiliations
1 Department of Child Health, Unit II, Christian Medical College, Vellore-632 004, IN
1 Department of Child Health, Unit II, Christian Medical College, Vellore-632 004, IN
Source
Journal of Clinical Pediatric Nephrology, Vol 1, No 1 (2013), Pagination:Abstract
No abstractReferences
- Khan FY. Rhabdomyolysis – A review of literature. J Med 2009; 67 :272-83.
- Mannix R, Lin M, Wright R, Baskin M. Acute Pediatric Rhabdomyolysis: Causes and Rates of Renal Failure. Pediatrics 2006; 118 : 2119-2125.
- Brown CV, Rhee P, Chan L, Evans K, Demetriades D, Velmahos GC. Preventing Renal Failure in Patients with Rhabdomyolysis: Do Bicarbonate and Mannitol Make a Difference? J Trauma 2004; 56:1191-1196.
- Sauret JM, Marinides G. Rhabdomyolysis. Am Fam physician 2002; 65:907-913.
- Mehmets RV, Sever UU, Erek E, Lamieire N. Rhabdomyolysis. J Am Soc Nephrol 2000; 11: 1553–1561.
- Steroid Withdrawal or Avoidance in Pediatric Kidney Transplantation
Abstract Views :266 |
PDF Views:0
Authors
Affiliations
1 Pediatric Nephrologist Christian Medical College, Vellore Tamilnadu, IN
2 Division of Pediatric Nephrology, Christian Medical College, Vellore, Tamilnadu, IN
1 Pediatric Nephrologist Christian Medical College, Vellore Tamilnadu, IN
2 Division of Pediatric Nephrology, Christian Medical College, Vellore, Tamilnadu, IN
Source
Journal of Clinical Pediatric Nephrology, Vol 2, No 2 (2013), Pagination: 11-18Abstract
Steroids have been a cornerstone of post kidney transplant immunosuppression and are effective in preventing and treating acute rejection. However steroid usage is associated with considerable morbidity including growth retardation, hyperlipidemia, hyperglycemia, hypertension, increased risk of acute infection, adverse effects on bone mineral metabolism and cosmetic side-effects. Initial attempts to withdraw steroids were associated with unacceptable rise in acute rejection rates and graft dysfunction. More recently with the availability of more potent immunosuppressive agents, the idea of steroid withdrawal/avoidance has become a safe and effective reality. The timing of steroid withdrawal is an important determinant and either polyclonal or monoclonal antibodies are usually used if early post-transplant withdrawal or avoidance is planned. This review summarises the recent evidence on the topic. Most of the protocols described have been shown to prevent steroid side effects while maintaining graft function.Keywords
Kidney Transplant, Children, Steroid Withdrawal, Steroid AvoidanceReferences
- KDIGO Guideline for Care of the Kidney Transplant Recipient, 2009.
- Reisman L, Lieberman KV, Burrows L and Schanzer H: Followup of cyclosporine-treated pediatric renal allograft recipients after cessation of prednisone. Transplantation 49: 76-80, 1990.
- https://web.emmes.com/study/ped/annlrept/2010_Report.pdf.
- Lau KK, Haddad MN, Berg GM, Perez RV and Butani L: Rapid steroid discontinuation for pediatric renal transplantation: A single center experience. Pediatr Transplant 11: 504-510, 2007.
- Grenda R, Watson A, Trompeter R and Tönshoff B: Early steroid withdrawal in paediatric kidney recipients after two-doses of daclizumab induction, tacrolimus and MMF versus tacrolimus, MMF and steroids—TWIST Study. Pediatr Transplant 13(S1): 154-155, 2009.
- Motoyama O, Hasegawa A, Ohara T, et al.: A prospective trial of steroid withdrawal after renal transplantation treated with cyclosporine and mizoribine in children: Results obtained between 1990 and 2003. Pediatr Transplant 9: 232-238, 2005.
- Motoyama O, Hasegawa A, Aikawa A, et al.: Final height in a prospective trial of late steroid withdrawal after pediatric renal transplantation treated with cyclosporine and mizoribine. Pediatr Transplant 16: 78-82, 2012.
- Höcker B, John U, Planik C, et al.: Successful withdrawal of steroids in pediatric renal transplant recipients receiving cyclosporine A and mycophenolate mofetil treatment: Results after four years. Transplantation 78: 228-234, 2004.
- Ellis D: Growth and renal function after steroid-free tacrolimusbased immunosuppression in children with renal transplants. Pediatr Nephrol 14: 689-694, 2000.
- Benfield MR, Bartosh S, Ikle D, et al.: A randomized doubleblind, placebo controlled trial of steroid withdrawal after pediatric renal transplantation. Am J Transplant 10: 81-88, 2010.
- McDonald RA, Smith JM, Ho M, et al.: Incidence of PTLD in Pediatric Renal Transplant Recipients Receiving Basiliximab, Calcineurin Inhibitor, Sirolimus and Steroids. Am J Transplant 8: 984-989, 2008.
- Pape L, Offner G, Kreuzer M, et al.: De novo therapy with everolimus, low-dose ciclosporine A, basiliximab and steroid elimination in pediatric kidney transplantation. Am J Transplant 10: 2349-2354, 2010.
- Delucchi A, Valenzuela M, Lillo AM, et al.: Early steroidwithdrawal in pediatric renal transplant: Five years of followup. Pediatr Nephrol 26: 2235-2244, 2011.
- Barletta GM, Kirk E, J.J. G, Rodriguez JF, Bursach SM and Bunchman TE: Rapid discontinuation of corticosteroids in pediatric renal transplantation. Pediatr Transplant 13: 571, 2009.
- Shapiro R, Ellis D, Tan HP, et al.: Anti-lymphoid Antibody Preconditioning and Tacrolimus Monotherapy for Pediatric Kidney Transplantation. J Pediatr 148: 813-818, 2006.
- Chavers BM, Chang CY, Gillingham KJ and Matas A: Pediatric Kidney Transplantation Using a Novel Protocol of Rapid (6-Day) Discontinuation of Prednisone: 2-year Results. Transplantation 88: 237-241, 2009.
- Sarwal MM, Yorgin PD, Alexander S, et al.: Promising early outcomes with a novel, complete steroid avoidance immunosuppression protocol in pediatric renal transplantation. Transplantation 72: 13-21, 2001
- Sarwal MM, Vidhun JR, Alexander SR, Satterwhite T, Millan M and Salvatierra OJ: Continued superior outcomes with modification and lengthened follow-up of a steroid-avoidance pilot with extended daclizumab induction in pediatric renal transplantation. Transplantation 76: 1331–1339, 2003.
- Li L, Chang A, Naesens M, et al.: Steroid-free immunosuppression since 1999: 129 pediatric renal transplants with sustained graft and patient benefits. Am J Transplant 9: 1362-1372, 2009.
- Sarwal MM, Ettenger RB, Dharnidharka V, et al.: Complete Steroid Avoidance Is Effective and Safe in Children With Renal Transplants: A Multicenter Randomized Trial With Three-Year Follow-Up. Am J Transplant 12: 2719-2729, 2012.
- Naesens M, Salvatierra O, Benfield M, et al.: Subclinical inflammation and chronic renal allograft injury in a randomized trial on steroid avoidance in pediatric kidney transplantation. Am J Transplant 10: 2730-2743, 2012.