Informatics Publishing Limited

Abdul Saleem Mohammad ¹, Swetha Devidi ², Nikhat Fatima ¹, Humera Badar ¹, Syeda Saba Sulthana ¹, Mohammad Akthar Sulthana ³, Nuha Rasheed ⁴

Affiliations
1 Department of Pharmaceutical Analysis and Quality Assurance, St. Mary’s Pharmacy College, Deshmukhi (V), Pochampally (M), Behind Mount Opera, Nalgonda (Dist)-508284, Telangana, IN
2 Department of Pharmaceutical Chemistry, St. Mary’s Pharmacy college, Deshmukhi (V), Pochampally (M), Behind Mount Opera, Nalgonda (Dist)-508284, Telangana, IN
3 Vivekananda Group of Institutions (Pharmacy Department), Near Ramoji Film City, Ranga Reddy District, Hyderabad, Telangana, 501511, IN
4 Department of Pharmaceutics, Nizam Institute of Pharmacy, Near Ramoji Film City, Pochampally (Mandal), Deshmukhi Village - 508284, Nalgonda Dist., Telangana, IN

Abstract

Quality is the primordial intention to any pharmaceutical industry and its products manufactured. The current interest in the pharmaceutical industry is to obtain best quality. Acquainted with a practice that puts us in common and routine convention ensured to deliver a quality that sounds globally in terms of a spoken quality is on the dais of pharmaceutical arena. Validation is the mean of catering enormous benefits to even more than the acceptable quality level which in the global standard scale. Validation is the art of designing and practicing the designed steps alongside with the documentation. Validation and quality assurance will go hand in hand, ensuring the through quality for the products. Process Validation emphasize on process design elements and maintaining process control during commercialization and communicate that process validation is an ongoing program and align process validation activities with product life cycle. Process validation also emphasizes the role of objective measures and statistical tools and analyses and emphasizes knowledge, detection, and control of variability and gives assurance on consistent of quality/productivity throughout life cycle of product additionally a view of validation against the quality assurance, drug development and manufacturing process has been discussed.

Keywords

Quality, Validation, Types of Validation, Process Validation, Protocol, Regulatory Basis, Master Plan.

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Abdul Saleem Mohammad ¹, Nikhat Fatima ¹, Humera Badar ¹, Syeda Saba Sulthana ¹, Chandan Mohanty ², Mohammad Akthar Sulthana ³

Affiliations
1 Department of Pharmaceutical Analysis and Quality Assurance, St. Mary’s Pharmacy College, Deshmukhi (V), Pochampally (M), Behind Mount Opera, Nalgonda (Dist)-508284, Telangana, IN
2 Department of Pharmaceutics, St. Mary’s Pharmacy College, Deshmukhi (V), Pochampally (M), Behind Mount Opera, Nalgonda (Dist)-508284, Telangana, IN
3 Vivekananda Group of Institutions(Pharmacy Department), Near Ramoji Film City, Ranga Reddy District, Hyderabad, Telangana, 501511, IN

Abstract

A review on Al-Hijamah (Cupping therapy) includes the detailed introduction, areas or points of hijamah that are cupped on the various parts of the human body with it's mutual benefits, types of it whether it is dry or massage or wet therapy. These types of therapies are varient from one another while bleeding of blood via wet cupping is possibly beneficial that it can heal many ailments of our body. The safety of this type of therapy is much appreciable which doesn't hurt or leave marks of the punctures on the body while cupping is performed. Much more new therapies were discussed under it related to organs and possible disease that can be cured by cupping. Lot of variance has been distinguished between blood donation and hijamah regarding their mutual remedies and advantages.

Keywords

Al-Hijamah, Cupping, Venesection, Cauterization.

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Fathima Qurratul Ayeen ¹, Ruheena Yasmeen ², Humera Badar ¹

Affiliations
1 Department of Pharmaceutical Analysis and Quality Assurance, Nizam Institute of Pharmacy, Deshmukhi (V), Pochampally (M), Behind Mount Opera, Yadadri Bhuvanagiri (Dist)-508284, Telangana, IN
2 Department of Pharm. D (Pharmacy Practice), Nizam Institute of Pharmacy, Deshmukhi (V), Pochampally (M), Behind Mount Opera, Yadadri Bhuvanagiri (Dist)-508284, Telangana, IN

Abstract

A novel simple, accurate, precise and selective high performance liquid chromatographic (HPLC) method was developed and validated for simultaneous estimation of Ritonavir and Lopinavir in tablet dosage form. An isocratic, reverse phase HPLC method was developed and validated using Hypersil C₁₈ (250 mm×4.6 mm i.d.) 5μm, column and orthophosphoric acid pH3 and methanol (40:60) as mobile phase and detection is carried out at a wavelength of 273nm.The retention time for RITO and LOPI were 3.3±0.1 min and 4.7±0.1min respectively. The method was validated with respect to linearity, precision, accuracy and robustness.

Keywords

Ritonavir, Lopinavir, HPLC, UV, Orthophosphoric Acid (OPA).

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