Informatics Publishing Limited

R. P. Singh ¹, Somya S. Sarkar ¹, Manoj Kumar ¹, Anish Saxena ¹, U. S. H. Rao ¹, Arun Bhardwaj ¹, Jalshri Desai ¹, Jitendra Sharma ¹, Amul Patel ¹, Yogesh Shinde ¹, Hemant Arora ¹, A. R. Srinivas ¹, Jaya Rathi ¹, Hitesh Patel ¹, Meenakshi Sarkar ¹, Arpita Gajaria ¹, S. Manthira Moorthi ¹, Mehul R. Pandya ¹, Ashwin Gujrati ¹, Prakash Chauhan ¹, Kuriakose A. Saji ¹, D. R. M. Samudraiah ¹, A. S. Kiran Kumar ²

Affiliations
1 Space Applications Centre, Indian Space Research Organisation, Ahmedabad 380 058, IN
2 Indian Space Research Organisation, Bengaluru 560 231, IN

Abstract

Thermal Infrared Imaging Spectrometer (TIS), which operates in the infrared spectral region (7-13 μm), is one of the five instruments on-board the Mars Orbiting Mission (MOM). TIS was designed to detect emitted thermal infrared radiation from the Martian environment, which would enable the estimation of ground temperature of the surface of Mars and also map its surface composition. TIS instrument is a grating-based spectrometer which has spatial resolution of 258 m at periapsis (372 km). TIS hardware was realized with light-weight miniaturized components (total weight 3.2 kg) with power requirement of 6 W. Observations from TIS instrument were carried out during Earth-bound manoeuvres and cruise phase operations of MOM and the results were found to be in agreement with the laboratory measurements.

Keywords

Aerosol Optical Thickness, Mars Orbiter, Minerals Detection, Thermal Infrared Spectroscopy.

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Aalap Patel ¹, Hitesh Patel ², Jignesh  Patoliya ²

Affiliations
1 Department of ECE, Charusat University, Changa, IN
2 Department of CSE, Charusat University, Changa, IN

Abstract

The development of brainwave-controlled mobile robots received a great deal of attention because they can support to bring mobility back to people with devastating neuromuscular disruption and thus improve their quality of life. It focuses on conceptualization and designing of complex systems in order to harness the power of mind in the form of brainwaves. In this paper, I presented a comprehensive up-to-date review of the complete systems, key techniques, and evaluation issues of brainwave-controlled robots. The proposed robot is fully automated and controlled using Beta wave (human brain attention) of MindWave sensor which is detected from brain signal. Simulation of practical and theoretical ElectroEncephalonGraphy technology is given in the paper.

Keywords

ElectroEncephalonGraphy (EEG), EEG Biosensor, NeuroSky® MindWave Mobile, Thinkgear Chip, RAW Data, Gamma, Beta, Alpha, Rapid-Eye-Movement(REM), Intel® Galileo Gen-2, Mind-Machine Interface (MMI).

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Rakesh P. Patel ¹, Grishma Patel ², Hitesh Patel ², Ashok Baria ²

Affiliations
1 S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Ganpat vidyanagar, Kherva, Mehsana-Gozaria Highway, PIN-390 001, Gujarat, IN
2 S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Ganpat vidyanagar, Kherva, Mehsana-Gozaria Highway, PIN-390 001, Gujarat, IN

Abstract

The purpose of this research was to develop a matrix-type transdermal therapeutic system

Containing drug Aceclofenac with different ratios of hydrophilic (hydroxyl propyl cellulose) and hydrophobic (ethyl cellulose) polymeric systems by the solvent evaporation technique by using 15 % w/w of dibutyl phthalate to the polymer weight, incorporated as plasticizer. Different concentrations of oleic acid and isopropyl myristate were used to enhance the transdermal permeation of Aceclofenac. The physicochemical compatibility of the drug and the polymers studied by differential scanning calorimetry and infrared spectroscopy suggested absence of any incompatibility. Formulated transdermal films were physically evaluated with regard to thickness, weight variation, drug content, flatness, tensile strength, folding endurance, percentage of moisture content and water vapour transmission rate. All prepared formulations indicated good physical stability. In-vitro permeation studies of formulations were performed by using Franz diffusion cells. Formulation prepared with hydrophilic polymer containing permeation enhancer showed best in-vitro skin permeation through rat skin (Wistar albino rat) as compared to all other formulations. The results followed the release profile of Aceclofenac followed mixed zero-order and first-order kinetics in different formulation. However, the release profile of the optimized formulation F9 (r2 = 0.9935 for Higuchi) indicated that the permeation of the drug from the patches was governed by a diffusion mechanism. Formulation F9 showed highest flux among all the formulations and 1.369 fold enhancements in drug permeation. These results indicate that the formulation containing 15 % of oleic acid with 10 % Isopropyl myristate give better penetration of Aceclofenac through rat skin.

Keywords

Aceclofenac, Transdermal Film, Permeation Enhancer, In-vitro Permeation Study.

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Hitesh Patel ¹, Jhanvi Patel ¹, Bhavana Raval ¹, Bharat Shah ¹

Affiliations
1 B.J.Medical College, Ahmedabad, Gujarat, IN

Abstract

Airway management of an adult patient with palatal defect is a challenging case to Anesthesiologist. We report an adult patient who is an operated case of nasopharyngeal Angiofibroma posted for palatal defect (3.5*4.5 cm) repair. It was a major surgery lasted for 10 hours involving free flap from radial aspect of forearm along with radial artery and repositioning on palatal defect and anastomosis with facial artery. Challenges involved in this case management were airway, analgesia and fluid electrolytes . Intraoperative period was uneventful. Patient was electively shifted to ICU for prophylactic ventilatory support with ETTube in situ post procedure because it being a major surgery with compromised airway with poor pharyngeal reflexes, copious secretions, bite block. Patient was postoperatively managed with adequate analgesia, sedation and relaxation and was extubated on 3rd postoperative day. The details would be discussed later.

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