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Ragya Eslavath ¹, V. Harikrishna ¹, N. Kosuru ¹, Goli Venkateshwarlu ¹, Manoranjan Sabat ¹, K. Kanakaiah ²

Affiliations
1 Venkateshwara Institute of Pharmaceutical Sciences, Cherlapally, Nalgonda, IN
2 Sharada College of Pharmacy, Anantaram, Bhuvanagiri, Nalgonda, IN

Abstract

The present study was carried out to determine the phytochemical screening revealed the presence of alkaloids, saponins, tannins, reducing sugar and cardiac glycosides in the leaves of Bougainvillea glabra. Antrhaquinones, flavonoids and terpenoids were absent in the flowers of Bougainvillea glabra. Along with estimated the Rf Value amino acid and spectral study used to determine the λmax, The Rf Value of amino acid is 0.70, λmax of found to be 368.5 nm, standard graph of water extract shows the regression equation as y=0.0003×-0.0001.

Keywords

Bougainvillea glabra, UV-Spectrophotometer, TLC Plates

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Goli Venkateshwarlu ¹, Ragya Eslavath ¹, Anasuri Santhosh ¹, Suma Gutha ¹, D. Ramakka ¹, S. Sankirthi ¹

Affiliations
1 Venkateshwara Institute of Pharmaceutical Sciences, Cherlapally, Nalgonda, A. P., IN

Abstract

Ancient days peoples are purely depends on herbal drugs. Why because at that time allopathic drugs are not available for peoples. Now a days both ayurveda and allopathic drugs are used. some chronic diseases are completely not eradicated by allopathic drugs. For this reason ayurvedic drugs are more preffered than allopathic drugs. In India 3000 plants used for the medicinal value. In general 6000 medicinal plants in India are in use in traditional, folklore and used as a herbal medicine. This article aims to provide a comprehensive review in ayurveda in the pharmacological aspects of Ficus religiosa. This plant is available in entire India and traditional system has been reported to posses various activities like fertility agent, feet cracks, eye diseases, heart strengthen, anti-inflammatory, antileprosy, spleen and hepatoprotective activity, hicups, antiasthamatic agent, antiemetic and improve the semen secretion etc .

Keywords

Medicinal Herbs, Ficus religiosa., Pharmacological Activities.

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Goli Venkateshwarlu ¹, Manoranjan Sabath ¹, G. Venugopal ¹, M. Sravanprasad ², Somsubhra Ghosh ³, Sama Bharathbhushanreddy ¹

Affiliations
1 Venkateshwara Institute of Pharmaceutical Sciences, Nalgonda, IN
2 Sriindu Institute of Pharmaceutical Sciences, Sheriguda, R.R Dist., IN
3 Nalanda College of Pharmacy, Nalgonda, IN

Abstract

The determination of surface tension of three selected marked juice formulations were carried out using Traube's Stalagnometer technique by drop number method which in turn aid in further identification, structural elucidation as well as determining chemical constituents. The formulation I (Lemon Juice), formulation II (Tamarind Juice) and formulation III (Orange Juice) were selected for the studies and were also evaluated to their same quantity mixture ration with distilled water combination for estimation of different composition. The main aim and rationale of study was to evaluate the surface tension of selected formulations with distilled water. The 10% formulation of mixture (I:II:III::1:1:1) with distilled water showed maximum surface tension (72 dyne/cm) and 10% formulation mixture with distilled water showed minimum surface tension ( 65 sdyne/cm) amongst other compositions. The results revealed that all the present composition values were less than standard. The 60% (74 sdyne/cm), 70% (67.8 dyne/cm), 80% (68.07 dyne/cm), 90% (71.8s dyne/cm) formulation mixture with distilled water showed approximately same surface tension value. In individual surface tension study, it was noted that formulation III i.e. tamarinds juice (60 dyne/cm) showed highest value and formulation I i.e. Orange Juice (61 dyne/cm) showed lowest value comparison between three formulations under laboratory conditions.

Keywords

Surface Tension, Juice Formulation, Drop Number Method, Traube's Stalagnometer.

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Kanakam Vijayabhaskar ¹, Goli Venkateshwarlu ¹, J. Bhaskar ¹, K. Srisailam ², More Swapna ³

Affiliations
1 Venkateshwara Institute of Pharmaceutical Sciences, Nalgonda. 508002, IN
2 Department of Pharmacy, Satavahana University, Karimnagar. 505001, IN
3 Vaagdevi College of Pharmacy, Warangal. 506001, IN

Abstract

a monotypic genus and belongs to the subfamily Caesalpinioideae of the family Leguminosae (Fabaceae), Tamarindus indica L., commonly known as Tamarind tree is one of the most important multipurpose tropical fruit tree species in the Indian subcontinent. antioxidative potential of the methanol extract of tamarindus indca was evaluated using various antioxidant assays, including DPPH, superoxide, nitric oxide (NO), hydroxyl radical scavenging and ironchelating activity. Total phenolic and flavonoid content of SM was also determined by a colorimetric method. The extract exhibited powerful free radical scavenging, especially against DPPH, hydroxyl radical scavenging and ironchelating activity as well as a moderate effect on NO and superoxide anions. The protective effects of methanol extract of SM were studied in carbon tetrachloride-reduced biochemical markers of hepatic injury such as glutamate pyruvate transaminase (SGPT), serum glutamate oxalaoacetate transaminase (SGOT), alkaline phosphatase (ALP), serum bilirubin, cholesterol alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. The increased level of HDL demonstrated dose dependant reduction in the in vivo peroxidation induced by CCl4. Degree of protection was measured by using biochemical parameters such as serum transaminase (GOT and GPT), alkaline phosphatase (ALKP) and bilirubin. Petroleum ether, Ethyl acetate and chloroform extracts did not show any effects. Results obtained in the present study suggest that Tamarindus indica elicits hepatoprotectivity through antioxidant activity on carbon tetrachloride- and paracetamol-induced hepatic damage in rats.

Keywords

Tamarindus indica Hepatoprotective Activity, Antioxidant Effect, Biochemical Parameters.

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Goli Venkateshwarlu ¹, E. Ragyanaik ¹, Kasireddy Swapna ¹, A. Santhosh ¹, Santhosh ¹

Affiliations
1 Venkateshwara Institute of Pharmaceutical Sciences, Cherlapally, Nalgonda, Andhra Pradesh-508001, IN

Abstract

Ancient days peoples are purely depend on herbal drugs. Why because at that time allopathic drugs are not available for peoples. Nowadays both ayurveda and allopathic drugs are used. Some chronic diseases are completely not eradicated by allopathic drugs. For this reason ayurvedic drugs are more preffered than allopathic drugs. In India 3000 plants used for the medicinal value. In general 6000 medicinal plants in India are in use in traditional, folklore and used as a herbal medicine. This article aims to provide a comprehensive review in ayurveda in the pharmacological aspects of Vitex trifolia usually having heat producing property, increase the bile secretion stomach along with develop the colour skin. This plant completely eliminates the kapha, vatha, pitha produced diseases. It also useful in cough, bronchitis, and antiamebic, antileprotic agent.

Keywords

Medicinal Plant, Vitex trifolia, A Pharmacological Activity.

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Goli Venkateshwarlu ¹, E. Ragyanaik ¹, G. Suma ¹, Anasuri Santosh ¹, Manaoranjan Sabat ¹

Affiliations
1 Venkateshwara Institute of Pharmaceutical Sciences, Cherlapally, Nalgonda, AP, IN

Abstract

Recently in government hospital we have investigated regarding various ailments like HIV, TB, uterus cancer and so on. Now days due to the stress conditions causes IBS it decreases the immune system develops various symptoms such as frequent motion, headache, GIT disturbances. For every 10 persons 6 persons are suffered with HIV. young generation participate in sex with infected female without protection, and with reused syringes, blades, shaving knifes produces for every 10 persons 4 persons suffering with HIV infection and where as in case of TB for every 10 person 3 persons suffering with TB. in case of uterus cancer for every 10 persons 3 persons are suffered with uterus cancer. This whole assessment done in Government Hospital, Gollaguda, Nalgonda urban areas, AP. in case of remote areas this ratios is in case of uterus cancer is more and as usually in case of IBS urban peoples are hugely suffered Along with HIV case in remote areas this ratio is high when compared with urban areas.

Keywords

IBS, Uterus Cancer, HIV, TB.

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