Informatics Publishing Limited

Muhammad Iqbal ¹, Muhammad Akram ², Muhammad Qaisar ², Yousaf Ali ², Hina Fazal ², Imam Bakhsh Baloch ¹, Musa Kaleem Baloch ³, Ghulam Mustafa ⁴

Affiliations
1 Institute of Chemical Sciences, Gomal University, Dera Ismail Khan, KPK, PK
2 Medicinal Botanic Centre, PCSIR Laboratories Complex Peshawar, PK
3 University of Sargodha, Punjab, PK
4 Faculty of Pharmacy, Gomal University, Dera Ismail Khan, KPK, PK

Abstract

Present study describes antifungal and antibacterial screening of the previously synthesized novel substituted benzyl 4-ketohexanoates (1-17) against two fungi and two bacteria. All of the substituted benzyl 4-ketohexanoates exhibited antimicrobial activities in terms of inhibition zones and Minimum Inhibitory Concentrations (MICs). Halogens substituted benzyl 4-ketohexanoates in general and Iodinated analogues showed maximum activity in terms of inhibitions zones as well as MICs.

Keywords

Antibacterial, Antifungal, Benzyl 4-ketohexanoates, MICs, Zones of Inhibition.

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