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Sumalatha, G.
- Evaluation of Anti-inflammatory and Analgesic potency of Whole Plant Extract of Solanum surattense in Experimental Animals
Abstract Views :278 |
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Authors
Affiliations
1 Department of Pharmacology, Hindu College of Pharmacy, Guntur, (A.P), IN
2 Department of Pharmacognosy, A. S. N College of Pharmacy, Guntur, (A.P), IN
3 Department of Pharmacology, Calcutta institute of pharmaceutical t A.H.S, Kolkata, IN
1 Department of Pharmacology, Hindu College of Pharmacy, Guntur, (A.P), IN
2 Department of Pharmacognosy, A. S. N College of Pharmacy, Guntur, (A.P), IN
3 Department of Pharmacology, Calcutta institute of pharmaceutical t A.H.S, Kolkata, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 5, No 2 (2013), Pagination: 101-105Abstract
The anti-inflammatory effect of the alcoholic extract of Solanum surattense whole plant was assessed in the carrageenan-induced rat paw edema, the antinociceptive effect of the alcoholic extract of Solanum surattense, plant was studied using thermal and chemical-induced pain models using animals, at the doses of 100 and 200 mg/kg body weight. The acute toxicity and the phytochemical constituents of the extract were also determined. The estimated LD50 of the extract was 2gm/kg body weight. Extract significantly (P<0.05), dose-dependently demonstrated anti-inflammatory activity against acute inflammation induced by carrageenan and also the extract significantly (P<0.05) prolonged the pain reaction times in tail flick pain model, and reduced acetic acid-induced writhing. Phytochemical analysis revealed the presence of alkaloids, saponins, flavanoids and carbohydrates in the plant.Keywords
Analgesic, Anti-inflammatory, Carrageenan, Acute Toxicity, Solanum Surattense
References
- Tripathi. K.D .Essentials of Medical Pharmacology. 4th Edition, published by Jaypee Brothers, New Delhi, 2002; 612-614.
- Singh N, Kapur KK and Singh SP. Mechanism of cardiovascular action of Terminalia arjuna . J Med Plant Res. 1982; 45:102-104.
- The Ayurvedic Formulary of India, Part-II, 2000, 1st edition, The Controller of Publications, Delhi, p.35.
- Baydar NG, Ozkan G, Sagdic O. Total phenolic contents and antibacterial activities of grape (Vitis vinifera L.) extracts. Food Control 2004; 15:335-339.
- Akoh CC, Bonilla EP, Sellappan S, Krewer G. Phenolic content and antioxidant capacity of Muscadine grapes. Journal of Agricultural and Food Chemistry 2003; 51:5497-5503.
- Frankel EN, Kanner J, German JB, Parks E, Kinsella JE. Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine. The Lancet 1993; 341(20):454- 457.
- Mayer AS, Yi OS, Person DA, Waterhouse DL, Frankel EN. Inhibition of human low density lipoprotein oxidation in relation to composition of phenolic antioxidants in grapes (Vitis vinifera). Journal of Agricultural and Food Chemistry 1997; 45:1638-1643.
- Teissedre PL, Frankel EN, Waterhouse AL, Peleg H, German GB. Inhibition of in vitro human LDL oxidation by phenolic antioxidants from grapes and wines. Journal of the Science of Food and Agriculture 1996; 70:55-61.
- Waterhouse AL. Wine antioxidants may reduce heart disease and cancer. Presentation of American Chemical Society, Washington; 1994.
- Renaud S, Lorgeril MD. Wine, alcohol, platelets and the French paradox for coronary heart disease. The Lancet 1992; 339:1523- 1526.
- Davalos A, Bortolome B, Gomez-cordoves C. Antioxidant properties of commercial grape juices and vinegars. Food Chemistry 2005; 93(2):325-330.
- Orhan DD, Orhan N, Ergun E, Ergun F. Hepatoprotective effect of Vitis vinifera L. leaves on carbon tetrachloride-induced acute liver damage in rats. Jornal of Ethnopharmacology 2007; 112:145-151.
- Corder R, Mullen W, Khan NQ, Marks SC, Wood EG, Carrier MJ, Crozier A. Red wine procyanidins and vascular health. Nature 2006;444:566.
- Mishra S. Bhaisazya Kalpana Vigyan. Varanasi, India: Chaukambha Surbharati Prakashan; 2005.p. 253-254.
- Alam M, Radhamani S, Ali U, Purushottam KK. Microbiological Screening of Dhataki Flowers. Journal of Research in Ayurveda and Siddha 1984; 2(4):371-375.
- Braugghler JM, Duncan CA and Chase IR. The involvement of iron in lipid peroxidation. J Biol Chem. 1986; 261(22): 10282- 89.
- Lowery OH, Rosenbrough NJ, Farr AL and Randall RJ. Protein estimation with Folin phenol reagent. Biol Chem. 1951;193:265-275.
- Khanna AK, Chander R and Kapoor NK. Terminala arjuna: an Ayurvedic cardiotonic, Regulates lipid metabolism in Hyperlipidemic rats. Phytother Res. 1996;10: 663-665.
- Allain CC, Poon LS, Chan CS and Richmond W. Enzymatic Determination of Total Serum cholesterol. Clin Chem .1974;20::447-475.
- Friedewald WT, Levy RI and Fredrickson DS. Estimation of concentration of low density cholesterol in plasma without use of ultracentrifuge. J Clin Chem .1972;18: 449-502.
- Muller PH, Schmulling RM, Liebich HM and Eggstein M. A fully Enzymatic Triglyceride Determination. J Clin Chem. 1977;15:457-464.
- Anne SM, Ock SY, Debra AP, Andrew LW and Edwin NF. Inhibition of Human Low Density Lipoprotein oxidation in relation to composition of Phenolic antioxidants in Grapes (Vitis Vinifera). J Agri Food Chem. 1997;45 (5):1638-1643.
- S Renaud, and M De Lorgeril. Wine, alcohol, Platelets and the French Paradox for Coronary Heart Disease. The Lancet. 1992; 339: 1523-1526.
- Pederson TR. Low- density lipoprotein cholesterol lowering is and will be the key to the future of lipid management. American J Cardiol. 2001; 87(5A): 8B-12B.
- Boden WE and Pearson TA. Raising low levels of High Density Lipoprotein Cholesterol is an important target of therapy. American J cardiol. 2000; 85(5):645-650.
- Antinephrolithiatic Potential of Macrotyloma uniflorum Aqueous Extract in Rats
Abstract Views :154 |
PDF Views:0
Authors
V. D. N. Srinivas
1,
G. Sumalatha
1,
P. P. V. Jagannath
1,
D. Siva Kishore
1,
P. Madhu Kiran
1,
M. Jhansi Rani
1
Affiliations
1 Department of Pharmacology, Hindu College of Pharmacy, Amaravathi Road, Guntur, Andhra pradesh, IN
1 Department of Pharmacology, Hindu College of Pharmacy, Amaravathi Road, Guntur, Andhra pradesh, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 1 (2010), Pagination: 75-78Abstract
Urolithiasis is a major health problem with its high morbidity, high cost of management and potential for end-stage renal disease. The aim of our study is to cure and prevent the recurrent stone formation. Herbal drugs claim many promising remedies in urolithiasis. An attempt is made in this direction in the current work by using Macrotyloma uniflorum. The experimental model selected for the present study is subcutaneous administration of gentamicin (40mg/kg/day) for 8 days and dietary supplementation with 5% ammonium oxalate starting at day 5 of the treatment regimen to induce calcium oxalate urolithiasis. On administration of aqueous extract of Macrotyloma uniflorum in preventive and curative groups, moderate to few crystals are observed along the mild appearance of edema and dilation in tubules and crystals are present focally indicating the ability of aqueous extract of Macrotyloma uniflorum to dissolve the preformed stones. The parameters monitored in the present study are Kidney weight, calcium and oxalate deposition in kidney and the histological studies support the calcium and oxalate deposition data in kidney. Thus aqueous extract of Macrotyloma uniflorum showed significant antinephrolithiatic activity.
Keywords
Urolithiasis, Macrotyloma Uniflorum, Calcium Oxalate Stones.- Applications of Energy Aware Routing Protocols in WSN
Abstract Views :183 |
PDF Views:2
Authors
Affiliations
1 Vignan's Lara Institute of Technology and Science, A.P., IN
2 Narasaraopeta Engineering College, A.P., IN
1 Vignan's Lara Institute of Technology and Science, A.P., IN
2 Narasaraopeta Engineering College, A.P., IN
Source
Oriental Journal of Computer Science and Technology, Vol 9, No 1 (2016), Pagination: 24-29Abstract
In this paper we have reviewed application of energy aware routing protocols like LEACH, LEACH-C, PEGASIS, BCDCP, ENPC-NPSO, ANPC etc In WSN sensors are randomly deployed in the sensor field which brings the coverage problem. Hence energy and coverage problem are very scarce resources for such sensor systems and has to be managed wisely in order to extend the life of the sensors and maximizing coverage for the duration of a particular mission. In past a lot of cluster based algorithm and techniques were used. In this paper we also find out all type of PSO based algorithm, their application and limitation over present techniques to overcome the problems of low energy and coverage of sensor range.Keywords
Wireless Sensor Networks, Energy Efficient Clustering, LEACH, Energy Efficient Algorithms, PSO Algorithm.Full Text
- Multi Node Recovery in Wireless Sensor Actor Networks
Abstract Views :141 |
PDF Views:2
Authors
Affiliations
1 Department of CSE, Vignan's LARA Institute of Technology and Science, Vadlamudi Guntur Dist., A.P., IN
1 Department of CSE, Vignan's LARA Institute of Technology and Science, Vadlamudi Guntur Dist., A.P., IN
Source
Oriental Journal of Computer Science and Technology, Vol 7, No 3 (2014), Pagination: 363-368Abstract
In wireless sensor-actor networks, the sensors sense the surroundings and transmit the sensed data to the actors. The actor nodes respond collectively to achieve their purpose. Since the actors and sensors have to communicate at all times, a strong network topology has to be established. A failure of an actor may cause the network to be broken into two. The solution can be provided by moving actor node thus restoring connectivity. Current recovery schemes consider only single node failure. This paper overcomes this shortcoming by recovering from multiple node failures through Least-Disruptive topology Repair (LeDiR) algorithm. LeDiR algorithm depends on the local view of each node about its neighbor to find the recovery plan.Keywords
Wireless Sensor-Actor Network(WSAN), Failure Recovery, Cut-Vertex.Full Text
- Super Porous Hydrogels – Supreme Drug Delivery
Abstract Views :180 |
PDF Views:0
Authors
Affiliations
1 Hindu College of Pharmacy, Amaravathi Road, Guntur, Andhra Pradesh, IN
2 Don Bosco PG College of Pharmacy, Pulladigunta, Guntur Dt, Andhra Pradesh, IN
1 Hindu College of Pharmacy, Amaravathi Road, Guntur, Andhra Pradesh, IN
2 Don Bosco PG College of Pharmacy, Pulladigunta, Guntur Dt, Andhra Pradesh, IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 8 (2011), Pagination: 1182-1188Abstract
Gastro retentive drug delivery system is developed mainly for those drugs that are having narrow therapeutic window and are absorbed mainly in the stomach. A number of controlled drug delivery systems are available to increase the gastric residence time of the drug namely muco adhesive /bio adhesive systems, high density ,magnetic systems, super porous hydrogels, raft systems, low density systems, floating ion exchange resins. Among these super porous hydrogels are one of the most promising drug delivery systems as they swell very fastly upto 200 times of their own weight. These swollen hydrogels remains in the stomach for prolonged periods and releases the loaded drugs. This unique swelling property allows them to be used as a gastric retention carriers provides sustained release. The present review mainly focuses on formulation ,preparation and characterization and applications of super porous hydrogels.Keywords
Super Porous Hydrogels (SPHs), Swelling, Monomers, Acrylates etc.- Opportunities and Challenges in High Mobility Wireless Communication- 5G
Abstract Views :149 |
PDF Views:2
Authors
Affiliations
1 Department of Computer Science, Nehru Arts and Science College, IN
2 Department of Computer Technology, Sri Krishna Arts and Science College, Coimbatore, IN
3 Department of Computer Science, Sri Krishna Arts and Science College, Coimbatore, IN
1 Department of Computer Science, Nehru Arts and Science College, IN
2 Department of Computer Technology, Sri Krishna Arts and Science College, Coimbatore, IN
3 Department of Computer Science, Sri Krishna Arts and Science College, Coimbatore, IN
Source
Wireless Communication, Vol 10, No 1 (2018), Pagination: 7-8Abstract
Wireless communication is used to be connection between two or more gadgets’ to share the data and information without physical wired connection. Frequently wireless communication starting 1G-4G (Now days using 4G network).In day to day life the internet users and user needs also increased. All technologies also upgraded in advanced versions. In networking field also expected in High Mobility Wireless communication (HMWC)-5G.5G network to support large amount of data as well as reliability and security. 5G network is expected to create “Network of networks”. Now a day user’s mostly using 3G and 4G networks. 3G networks support multimedia services but power consumption is high and then after 4G networks was introduced.4G network have a high data transfer rate to reach in 100Mpbs. It is supports LTE (Long Term Evolution)for data as well as voice. But, 5G network provide broadcasting of data in Gigabit (Gbps) which supporting almost 65,000 connections. This paper focuses on opportunities and challenges in 5G, avoidance of network traffic and data delivery speed of the users.
Keywords
High Mobility Wireless Communication, Long Term Evolution, Mpbs, Gigabit.References
- White Paper V2.0H 5G Enabler: High Mobility Support, Future mobile communication forum,2016.4
- C.-L. I, S. Han, Z. Xu, S. Wang, Q. Sun, Y. Chen. New Paradigm of 5G Wireless diversity, mobility adaptation) and mitigate the impairments Mar. 2016, 34(3): 474-482.
- IMT-2020 (5G) Promotion Group. (May 2015).5G Network Technology Architecture White Paper. [Online]. Available: http://www.imt-2020.org.cn/en
- GPP TR 38.913: Study on Scenarios 3GPP TR 38.913: Study on Scenarios and
- China Communications Supplement No.2 2016 12 Requirements for Next Generation AccessTechnologies, June. 2016.
- P. Fan. Advances in broadband wireless communications under high mobility scenarios [J]. Chin. Sci. Bull., Dec. 2014, 59(35): 4974-4975.
- J. Wu and P. Fan. A Survey on High Mobility Wireless Communications: Challenges, Opportunities and Solutions [J]. IEEE ACCESS, Mar.2016, Vol.4: 450-476.
- K. Zheng, L. Zhao, J. Mei, M. Dohler, W. Xiang,and Y. Peng, 10 Gb/s HetSNets with millimeter-wave communications: Access and networking challenges and protocols [J]. IEEE Commun.Mag., Jan. 2015, 53(1): 222-231.