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G. Mathubala ¹, N. Babitha ¹

Affiliations
1 Bharath University, Selaiyur, Chennai – 600 073, IN

Abstract

(1)N-Nitroso-t[3]-methyl-r[2],c[6]-diphenyl piperidin-4-one was prepared; the procedure of Noller and Baliah was followed to prepare the compound [1]. By taking solution of the compound in a suitable solvent, NMR measurements were taken.

Keywords

Ammonium Acetate, Ammonia, Anhydrous, Benzaldehyde, Crush, Drop-wise, Extract, Melting Point, Petroleum Ether, Stirring Preparation of Compounds N – Nitroso - T[3] – Methyl -r[2],c[6]-diphenylpiperidin – 4 – one [59]

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G. Mathubala ¹, V. Krishnasamy ¹

Affiliations
1 Bharath University, Selaiyur, Chennai–600 073, IN

Abstract

Some six and seven membered saturated hetero cyclic compounds were prepared. 1H NMR spectra were recorded in DMSO - d6. The chemical shifts were compared with those in CDCl3. The COSY, NOESY and 13C‒1H correlation spectra had been recorded to assign the signals unambiguously. The coupling constant of benzylic proton with one of the vicinal proton was found to be zero. The buttressing effect of alkyl groups was also studied. The chemical shift values, area of the signals, multiplicity, COSY and NOESY spectra were used to assign the signals. Further COSY and NOESY and 13C‒1H correlation spectra were also used. The solvent effect, concentration effect, and temperature effect were also studied using DMSO- d6 and CDCl3 α- effect and polar nature of the neighbouring group were also studied.

Keywords

Assignment, Chemical Shift, Correlation, Isopropyl, Multiplets, NOE, Peak, Signal

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S. Rosy Christy ¹, G. Mathubala ¹

Affiliations
1 Department of Chemistry, Bharath University, Selaiyur, Chennai - 600 073, IN

Abstract

Some six and seven membered saturated hetero cyclic compounds were prepared; from their vicinal coupling constants, proton - proton Torsional angles were calculated using Altona's Equation. 1H NMR spectra were recorded in DMSO - d6. The chemical shifts were compared with those in CDCl3. The COSY, NOESY and 13C-1H correlation spectra had been recorded to assign the signals unambiguously. Thereafter, torsional angles were calculated using electronegativity values of the substituents; the electronegativity value of oxygen was taken to be 3.50. Calculations were made accurately.

Keywords

Altona’s Equation, COSY, NOESY, Orientatin, Conformation

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