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Edeh Imomotimi, E.
- The Effect of some Antimalarial Drugs on Human Serum Lactate Dehydrogenase (LDH) Activity
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Authors
Affiliations
1 Department of Biochemistry, University of Port Harcourt, PMB -5323, PHC, R/S, NG
2 Department of Biochemistry, Madonna University, PMB-48, Elele, R/S, NG
1 Department of Biochemistry, University of Port Harcourt, PMB -5323, PHC, R/S, NG
2 Department of Biochemistry, Madonna University, PMB-48, Elele, R/S, NG
Source
Indian Journal of Drugs and Diseases, Vol 1, No 9 (2012), Pagination: 213-217Abstract
The invitro study on the effect of the antimalarial drugs; Chloroquine, Lariam, Camoquine, Quinine, Halfan and Fansidar on human serum lactate dehydrogenase activity was investigated at pH 7.5., results obtained revealed that chloroquine had little or no significant effect on the enzyme lactate dehydrogenase activity while others (lariam, camoquine, quinine, halfan, and fansidar) activated the enzyme in a concentration dependent manner.Keywords
Drugs, Anti-malarial, Activity, Concentration, Enzyme, Inhibition, DiagnosisReferences
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