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Satynarayana, D.
- Preparation and Evaluation of Niosomes of Brimonidine Tartrate as Ocular Drug Delivery System
Abstract Views :203 |
PDF Views:122
Authors
P. Prabhu
,
Marina Koland
,
K. Vijaynarayan
,
Nm. Harish
,
D. Ganesh
,
Rn. Charyulu
,
D. Satynarayana
Source
Asian Journal of Pharmaceutical Research and Health Care, Vol 2, No 4 (2010), Pagination: 293-301Abstract
Nioosomes of brimonidine tartrate were prepared by film hydration method. The prepared vesicles were evaluated for photomicroscopic characteristics, entrapment efficiency, in vitro, ex- in vitro drug release, in vivo intra ocular pressure lowering activity. Methods employed for the preparation of vesicles were found to be simple and reproducible, produced vesicles of acceptable shape and size with unimodal frequency distribution pattern. The in vitro, ex-in vitro drug release studies showed that there was a slow and prolonged release of drug which followed zero order kinetics. The intra ocular pressure lowering activity of prepared formulations were determined and compared with pure drug solution. It was found that intra ocular pressure lowering action was sustained for longer period of time. Stability study data revealed that the formulations were found to be stable when stored at refrigerator temperature (2 °C to 8 °C) and at 25 °C with no change in shape and drug content. Results of the study indicated that it is possible to develop a safe and physiological effective topical niosomal formulation which is patient compliance.Keywords
Niosome, Film Hydration, Bromonidine Tartrate, Intra Ocular Pressure.- Isolation, Charectrisation and Screening of Antioxidant Activity of the Roots of Syzygiumcuminii (L) Skeel
Abstract Views :139 |
PDF Views:0
Authors
Affiliations
1 Department of Pharmaceutical Chemistry Nitte, Gulabi, Shetty, Memorial, Institute of Pharmaceutical Sciences, Mangalore-574160 Karnataka, IN
1 Department of Pharmaceutical Chemistry Nitte, Gulabi, Shetty, Memorial, Institute of Pharmaceutical Sciences, Mangalore-574160 Karnataka, IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 2 (2009), Pagination: 218-221Abstract
We present here in vitro antioxidant activity of butanolic extract of the ischolar_main’s of Syzygium cuminii (L) skeel belonging to the family myretacea. Antioxidant activity was determined by two in vitro methods- reducing power and DPPH. Activity-guided fraction leads to the isolation of three constituents; the results are compared with standard ascorbic acid. The further study is in progress to isolate these constituents in higher quantity and to screen them for antidiabetic and antioxidant activity in pure isolated chemical constetuent.Keywords
Butanolic, Syzygium Cuminii(L) Skeel, Myretaceae, Antioxidant, Antidiabetic.- The Status of Electronic Journals in India from 2006-2015-A Brief Study
Abstract Views :297 |
PDF Views:12
Authors
Affiliations
1 Telangana University, Nizamabad - 503322, Telangana, IN
1 Telangana University, Nizamabad - 503322, Telangana, IN
Source
Journal of Information and Knowledge (Formerly SRELS Journal of Information Management), Vol 55, No 3 (2018), Pagination: 157-161Abstract
Electronic journals in India have grown exponentially. The aim of this work is to examine the nature and growth of electronic journals that have been assigned ISSN from 2006 to 2015 by National Science Library, New Delhi. It covers a total of 5979 electronic journals with assigned ISSN.Keywords
Electronic Journals, India, ISSN.References
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- National Science Library (2016). International Standard Serial Number. Retrieved on 14-06-2016. http://nsl.niscair.res.in/issn.jsp.
- Omotayo, B. O. (2011). Access, Use, and Attitudes of Academics toward Electronic Journals: A Case study of Obafemi Awolowo University, Ile-Ife. Library Philosophy and Practice.
- Tenopir Carol, & Donald W King. (October 2002). Reading Behaviour and Electronic Journals. Learned Publishing, 15(4), 259-265. https://doi.org/10.1087/095315102760319215.