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Panda, D.
- In Silico Structural Analysis and Characterization of Human Kiss-1 Receptor: A Metastasis Suppressor Protein in Melanomas and Breast Cancer
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Authors
Affiliations
1 Department of Bioinformatics, BJB (A) College, Bhubaneswar-751014, IN
2 Konark Institute of Science and Technology, Techno Park, Jatni, Bhubaneswar-752050, IN
3 Research & Development Center, Hi-Tech Medical College and Hospital, Bhubaneswar- 751010, IN
1 Department of Bioinformatics, BJB (A) College, Bhubaneswar-751014, IN
2 Konark Institute of Science and Technology, Techno Park, Jatni, Bhubaneswar-752050, IN
3 Research & Development Center, Hi-Tech Medical College and Hospital, Bhubaneswar- 751010, IN
Source
Journal of Endocrinology and Reproduction, Vol 16, No 2 (2012), Pagination: 57-64Abstract
Metastasis, a major cause of death in cancer patients, involves the spread of a tumor or cancer to distant parts of the body as primary cancer, invasion of surrounding tissue, spread through circulation, re-invasion and proliferation in distant organs. KiSS1 is a metastasis-suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas, without affecting tumorigenicity and also may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. To understand the operational mechanism, structural model is always important. Therefore, in present study a complete structural analysis and three- dimensional (3D) modeling of KiSS-1 receptor, with a molecular weight of 42,586 kDa, of Homo sapiens was carried out. The 398 amino acid sequence of the KiSS-1 receptor protein was retrieved from Uniprot KB database (Acc. no: Q969F8). Based on the PDB Blast result and analysis the three-dimensional structure of KiSS-1R was predicted by using the SWISS MODEL, ESyPred 3D protein comparative modeling server. The predicted model was further assessed by Rampage, VERIFY-3D and PROCHECK graph with acceptable scores. The overall result provides evidence of good quality of model and furnishes an adequate foundation for functional analysis of experimentally derived crystal structures and also helps in understanding metastasis.Keywords
KiSS-1R, BLASTp, SWISS MODEL, UniProtKB, SAVES Server.- Effect of Pesticidal Schedule to Control the Shoot and Fruit Borer Leucinodes orbonalis in Brinjal
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Authors
Affiliations
1 Krishi Vigyan Kendra (O.U.A.T.), Larkipalli, Bolangir (Odisha), IN
1 Krishi Vigyan Kendra (O.U.A.T.), Larkipalli, Bolangir (Odisha), IN
Source
International Journal of Plant Protection, Vol 8, No 2 (2015), Pagination: 347-351Abstract
To study the performance of various pesticidal schedules to evolve a suitable management strategy against brinjal shoot and fruit borer, the field experiment was carried out at The Central Research Station, OUAT, Bhubaneswar from January to June 2010. The findings of investigation revealed that the brinjal shoot and fruit borer caused highest fruit damage (80.22%) at 120 days after transplanting under unprotected condition. Under protected condition, the mean fruit infestation due to shoot and fruit borer varied from 46.44 to 53.15 per cent. Among all the treatment schedule, application of cartap hydrochloride, monocrotophos, carbaryl, azadirachtin, Bt formulation and triazophos at 30, 45, 60, 75, 90 and 105 days after transplanting at 15 days interval reduced the fruit infestation successfully and registered highest fruit yield and highest monetary value (Rs. 36,070/ha).Keywords
Borer, Brinjal, B: C, Days After Transplanting, Economics.References
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- Electric Ray Narcine timlei (Torpediniformes:Narcinidae) from Chilika Lagoon, Odisha, India
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Authors
C. M. Roshith
1,
R. K. Manna
1,
V. R. Suresh
1,
D. Panda
1,
A. P. Sharma
1,
A. Roy Chowdhury
1,
M. Mukherjee
1,
S. K. Banik
1
Affiliations
1 Central Inland Fisheries Research Institute, Barrackpore, Kolkata 700 120, IN
1 Central Inland Fisheries Research Institute, Barrackpore, Kolkata 700 120, IN