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Kilimozhi, D.
- Anti-Ovulatory and Abortifacient Potential of the Ethanolic Extract of Henna Roots in Rats
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Affiliations
1 Department of Pharmacy, Annamalai University, Annamalai Nagar-608002, Tamil Nadu, IN
1 Department of Pharmacy, Annamalai University, Annamalai Nagar-608002, Tamil Nadu, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 1, No 1 (2009), Pagination: 18-20Abstract
The rise in population in the developing world is over whelming and this intensifies the need for effective birth control measures. The synthetic agents available today for fertility control produce severe side effects. Such as hormonal imbalance, hypertension, increased risk of cancer and weight gain. Thus there is a need to replace these agents by safe and effective agents such as plants based contraceptive agents.
Therefore, the present study was under taken to explore the abotifacient and antiovulatory activity of ethanol extract of henna ischolar_mains. Thus, the successive ethanolic extract showed promising strong abotifacient and antiovulatory activity was observed at dose level of 400mg/kg body weight. Histological studies were carried out to confirm this effect.
Keywords
Abortifacient, Ovulation, Contraception.
References
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- Effect of Delonix elata on Adjuvant Induced Arthritis in Rats - A Radiographic Densitometric Analysis
Abstract Views :299 |
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Authors
Affiliations
1 Department of Pharmacy, Annamalai University, Annamalai Nagar-608002, Tamil Nadu, IN
2 Department of Radiology, Rajah Muthiah Medical College and Hospital, Annamalai University, Annamalai Nagar-608002, Tamil Nadu, IN
1 Department of Pharmacy, Annamalai University, Annamalai Nagar-608002, Tamil Nadu, IN
2 Department of Radiology, Rajah Muthiah Medical College and Hospital, Annamalai University, Annamalai Nagar-608002, Tamil Nadu, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 1, No 1 (2009), Pagination: 25-30Abstract
In the present study, the anti-arthritic effect of oral administration of ethanolic extract of Delonix elata on Freund's adjuvant induced arthritis has been studied in Wistar albino rats. The loss of body weight during the arthritic condition was corrected on treatment with ethanolic extract of Delonix elata at 250 and 500 mg.kg-1 body weights. The swelling of the paws during the secondary lesions was also markedly reduced on treatment with ethanolic extract of Delonix elata and this results was confirmed using radiographic analysis and the changes in the density of Hind Limb Bone Mass (HLBM) was measured using photodensitometer and aluminium step wedge. The HLBM was significantly reduced on treatment with ethanolic extract (250 and 500 mg·kg-1 body weight) of Delonix elata and standard drug Indomethacin (10 mg·kg-1). From the result we observed that the ethanolic extract of Delonix elata possess potent anti-arthritic activity.Keywords
Delonix elata, Anti-Arthritic, Freund's Complete Adjuvant, Photodensitometer, Aluminium Step Wedge.References
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- Active Principles Determination by GC/MS in Delonix elata and Clerodendrum phlomidis
Abstract Views :174 |
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Authors
Affiliations
1 Department of Pharmacy, Annamalai University, Annamalai Nagar-608002, Tamil Nadu, IN
1 Department of Pharmacy, Annamalai University, Annamalai Nagar-608002, Tamil Nadu, IN