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Galib Ruknuddin ¹, B. J. Patgiri ¹, P. K. Prajapati ¹, B. K. Ashok ², B. Ravishankar ³

Affiliations
1 Department of Rasa Shastra and Bhaishajya Kalpana, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, Gujarat, IN
2 Drug Discovery Group, R&D Centre, The Himalaya Drug Company, Makali, Bangalore, IN
3 SDM Centre for Research in Ayurveda and Allied Sciences, Kuthpady, Udupi, Karnataka, IN

Abstract

Introduction: Arthritis is the most common cause of disability, limiting the activities of adults throughout the world. Apart from the conventional treatment strategies using non-steroidal anti-inflammatory drugs, disease-modifying anti-rheumatic drugs, and glucocorticoids, newer and safer drugs are continuously being searched, as long-term usage of these drugs have resulted in adverse effects. Besides this, currently a number of medicinal plants are under scientific evaluation to develop a promising remedy in these cases. There is a need to investigate the complete therapeutic potential of these herbals for providing newer and safer treatment options with minimum side effects. Considering this, a polyherbal Ayurvedic compound formulation (Dashanga Ghana) has been studied in experimental animals to evaluate anti-arthritic activity. Materials and Methods: Dashanga Ghana has been prepared in the laboratory by following standard guidelines. Charles Foster albino rats were used to evaluate the activity through Freund’s adjuvant induced arthritis model. Results and Conclusions: Dashanga Ghana is found to possess significant anti-arthritic activity. Further studies are required to identify and characterize exact active phyto-constituents and to elucidate the exact mechanism of action, which is responsible for the observed pharmacological profile.

Keywords

Arthritis, Ayurveda, Dashanga Ghana, Freund’s Adjuvant, Paw Oedema.

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V. N. Shailaja ¹, B. Ravishankar ¹, B. E. Narkhede ²

Affiliations
1 Department of Industrial Engineering and Management, BMS College of Engineering, Bull Temple Road, Basavanagudi, Bengaluru - 560019, Karnataka, IN
2 Department of Production and Industrial Engineering, VJTI Matunga, H R Mahajani Marg, Matunga, Mumbai - 400031, Maharashtra, IN

Abstract

Noise is generated virtually by all processes. It is identified as an important pollutant. It causes discomfort to human beings and affects society too. This aspect has attracted many researchers to carry noise based research in urban environments. This paper attempts to establish data of various noise sources in Bangalore city, India. The study investigates various models and materials which exhibits absorption properties. The aim is to identify the best model and material which can help develop a good noise solution. Sustainable materials are also being used. Experiments are conducted using simulated noise conditions and on live engineering process. Materials exhibited varying damping properties with respect to ambient parameters. The experiments witnessed utilization of sound level meters and also 4 channel noise analyzer (4CNA). Noise data gathered are analyzed through tabulated results and meaningful graphs. Scientific analyses are made on the noise absorption properties of materials. The findings will augment engineering solutions for household and industries. Furthermore the study addresses the analyses of the stress levels of human beings due to various inputs.

Keywords

Ambient Noise, Barriers, Damping Materials, 4CNA, SL4010

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P. K. Sarkar , P. K. Prajapati , V. J. Shukla , B. Ravishankar

Abstract

Aconite is one of the poisonous plants used therapeutically in practice of Ayurveda after proper treatment called as ‘Shodhana’. To determine the effect of Shodhana treatment on chronic toxicity and to assess the effect of recovery period after chronic toxicity of aconite. Raw aconite (RV), urine treated aconite (SM), and milk treated aconite (SD) were administered in 6.25 mg/kg dose in Charles Foster strain albino rats for 90 days for chronic toxicity. Six rats from each were kept for another 30 days without test drugs treatment to observe recovery from chronic toxicity. RV was found to be highly toxic in chronic exposure, SM had no apparent toxicity, but SD had mild toxicity in kidney. The toxicities of RV and SD were reversible, but sudden withdrawal of SM caused adverse effects, suggestive of tapering withdrawal. Shodhana treatments remove toxic effects from raw aconite. Chronic toxicity of aconite is reversible. Confirmed the arrangement of abstract

Keywords

Aconitum chasmanthum, cow’s urine, cow’s milk, recovery, shodhana

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