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Surya Kiran, B. V. V. S.
- Evaluation of anthelmintic activity of Eichhornia crassipes ischolar_mains
Abstract Views :332 |
PDF Views:2
Authors
Affiliations
1 KLR Pharmacy College, Paloncha, Khammam, Andhra Pradesh, IN
2 Koringa College of Pharmacy, Korangi-533 461, E.G. Dt., Andhra Pradesh, IN
3 Pydah College of Pharmacy, Patavala, E.G.Dt., Andhra Pradesh, IN
1 KLR Pharmacy College, Paloncha, Khammam, Andhra Pradesh, IN
2 Koringa College of Pharmacy, Korangi-533 461, E.G. Dt., Andhra Pradesh, IN
3 Pydah College of Pharmacy, Patavala, E.G.Dt., Andhra Pradesh, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 5, No 3 (2013), Pagination: 183-184Abstract
Herbal medicine is having very old history. Plants are the typical manufacturers of complex drug molecules, which serve as a prototype to develop more effective and less toxic medicines. Helminth infections are distressing huge population in the world. These infections are contributing to the disorders like pneumonia, anaemia, eosinophilia and under nourishment. Anthelmintics are the drugs which expels the parasitic worms from the gastrointestinal tract by either paralyzing or killing the worms. So, there is a need of investigation of new anthelmintic molecules. Eichhornia crassipes belongs to the family Pontederiaceae, commonly known as "Water hyacinth" is selected as test drug based on ethno-botanical survey conducted in East Godavari Dist., Andhra Pradesh. In present study evaluation of anthelmintic activity of ischolar_main extracts was done by using adult Indian earth worm Pheritima posthuma. The above activity was carried out using the petroleum ether, ethanol extracts of different concentrations using piperazine citrate positive control and normal saline as negative control. Overall anthelmintic activity revealed that concentration dependent nature of extracts. The extract shows potent and significant anthelmintic activity as compared to the standards and it was investigated to be used as effective anthelmintic drug.Keywords
Helminth Infections, Anthelmintics, Eichhornia crassipes, Pheritima posthuma, Petroleum Ether & Ethanol ExtractReferences
- Bundy DA. Immunoepidemiology of intestinal helminthic infection: The global burden of intestinal nematode disease. Trans Royal Soc Trop Med Hyg 1994; 8: 259-61.
- k.d. tripathi; Essentials of medicinal pharmacology , 6th edition, 808.
- Van Riet et al. Chronic helminth infections induce immuno modulation: consequences and mechanisms Immunobiology, 2007, 212(6):475-9
- V. J. Theodorides et al., Anthelmintic Activity of Albendazole against Liver Flukes, Tapeworms, Lung and Gastrointestinal Roundworms.
- Kushwaha and Aind; Anthelmintic activity of polyherbal preparations, international journel of pharmacy and life sciences, May, 2010; 35-37
- Shanab SM, Shalaby EA, Lightfoot DA, El-Shemy HA. Allelopathic effects of water hyacinth [Eichhornia crassipes]. PLoS One 2010; 5:13200.
- El-Shemy HA, Aboul-Enein AM, Aboul-Enein KM, jita K. Willow leaves’ extracts contain anti-tumor agents effective against three cell types. PLoS One 2007; 2:178.
- Thorn G.M, Harrison‘s Principles of internal Medicine, 1977, Mc Grew Hill, New York.
- AA Kale et al; JP Salvekara. J. Chem. Pharm. Res., 2011, 3(2), 298-302.Y Shivhare et al J. Chem. Pharm. Res., 2011, 3(1), 488-491.
- Evaluation of antimicrobial and anthelmintic activities of the aerial parts of Elephantopus scaber L.
Abstract Views :398 |
PDF Views:2
Authors
Lakshmi Kanta Kanthal
1,
B. V. V. S. Surya Kiran
1,
K. Satyavathi
1,
P. Bhoja Raju
1,
Subhas Sahoo
2
Affiliations
1 Koringa College of Pharmacy, Korangi, Tallarevu [M], E. G. Dist. - 533 461, A.P, IN
2 Pulla Reddy Institute of Pharmacy, Annaram, Jinnaram (M), Medak Dist., A.P., IN
1 Koringa College of Pharmacy, Korangi, Tallarevu [M], E. G. Dist. - 533 461, A.P, IN
2 Pulla Reddy Institute of Pharmacy, Annaram, Jinnaram (M), Medak Dist., A.P., IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 5, No 3 (2013), Pagination: 193-196Abstract
Herbal medicine is having very old history. Plants are the typical manufacturers of complex drug molecules, which serve as a prototype to develop more effective and less toxic medicines. The antimicrobial activities of medicinal plants can be attributed to the secondary metabolites such as alkaloids, flavonoids, tannins, terpenoids that are present in these plants. Helminthes infections are becoming a cause to disorders like eosinophilia, pneumonia, anaemia, and under nourishment. Anti-helmethic drugs will expel these worms by paralyzing or by killing the worms. In traditional system of medicine a large number of plants are claimed to have anthelmintic activity. Chemical study started from 1960's and showed that constituents of E. scaber L. include flavonoids, triterpenoids, flavonoid esters and sesquiterpene lactones. Elephantopus scaber L. belongs to the family Asteraceae. The present study was carried out to screen the antimicrobial and anthelmintic activities of Elephantopus scaber L. The activities of extracts of the plant material are compared with the piperazine citrate. The n-hexane, chloroform and methanolic extracts shows concentration dependent and significant anthelmintic activity compared to the piperazine citrate and Albendazole and Amoxicillin and Fluconazole for the case of antimicrobial activity. Thus the anthelmintic and antimicrobial activities of Elephantopus scaber L. are demonstrated for the first time.Keywords
Elephantopus scaber L, Antimicrobial Activities, Antihelmethic Drugs, Pheritima posthumaReferences
- Thomson, W.A.R., 1978. Medicines from the Earth. Maidenhead, United Kingdom. McGraw-Hill Book Co.
- Stockwell, C., 1988. Nature’s pharmacy. London, United Kingdom. Century Hutchinson Ltd.
- Gerhartz, W., Y.S. Yamamota, F.T. Campbell, R. Pfefferkorn and J.F. Rounsaville, 1985. Ullmann’s Encyclopedia of Industrial.
- Srivastava, J., J. Lambert and N. Vietmeyer, 1996.. Medicinal plants: An expanding role in development. World Bank Technical Paper. No. 320.
- Uniyal, S.K., K.N. Singh, P. Jamwal and B. Lal, 2006. Traditional use of medicinal plants among the tribal communities of Chhota Bhangal, Western Himalayan. J. Ethnobiol. Ethnomed, 2: 1-14.
- Reddy PS, Jamil K and Madhusudhan P. Antibacterial activity of isolates from Piper longum and Taxus baccata. Pharma. Biol. 39, 236-238 (2001).
- Ateb DA and ErdoUrul OT Antimicrobial activities of various medicinal and commercial plant extracts. Turk. J. Biol. 27, 157- 162 (2003).
- Sher A; Antimicrobial activity of natural products from medicinal plants. Gomal J Med Sci.; 7(1):72-78 (2009)
- Thorn G.M, Harrison‘s Principles of internal Medicine, 1977, Mc Grew Hill, New York
- AA Kale et al; JP Salvekara. J. Chem. Pharm. Res., 2011, 3(2), 298-302.
- Y Shivhare et al J. Chem. Pharm. Res., 2011, 3(1), 488-491.
- Lee K H, Cowherd C M and Wolo M T. Antitumor agents. XV: deoxyelephantopin, an antitumor principle from Elephantopus carolinianus Willd. J Pharm Sci 1975, 64, 1572–3.
- Fuchino H, Koide T, Takahashi M, Sekita S and Satake M. New sesquiterpene lactones from Elephantopus mollis and their leishmanicidal activities. Plant Med 2001, 67, 647–53
- Rajkapoor B, Jayakar B and Anandan R. Antitumor activity of Elephantos scaber Linn. Against Dalton’s Ascitic Lymphoma. Indian J Pharm Sci., 2002, 64, 71 – 73
- A Study on Rheumatic Heart Disease Prevalence and Cardiovascular Outcomes among Children
Abstract Views :314 |
PDF Views:0
Authors
Affiliations
1 Koringa College of Pharmacy, Korangi-533 461, E.G. Dt., Andhra Pradesh, IN
2 KLR College of Pharmacy, Paloncha, Khammam, Andhra Pradesh, IN
1 Koringa College of Pharmacy, Korangi-533 461, E.G. Dt., Andhra Pradesh, IN
2 KLR College of Pharmacy, Paloncha, Khammam, Andhra Pradesh, IN
Source
Asian Journal of Nursing Education and Research, Vol 3, No 3 (2013), Pagination: 139-141Abstract
Rheumatic heart disease (RHD) remains a major contributor to morbidity and mortality in developing countries. In the present study, cross-sectional survey is designed to determine the prevalence of RHD in children from private and public schools between the age of 5 and 15 years in urban and rural areas of East Godavari District of Andhra Pradesh using both cardiac auscultation and echocardiographic evaluation. This study describes a comprehensive approach to implement echocardiographic screening in a high prevalence region as recommended by the WHO and outlines a robust analysis plan to investigate clinical outcome with secondary prevention for subclinical RHD. Even though the population attributable risk of RHD is expected to be high, false-positive screening results may occur. In order to reduce false-positive findings, all echocardiographic clips with borderline or definite RHD will be assessed from two independent cardiologists. Moreover, screening in a large population of schoolchildren might yield in exceptional cases important incidental clinical findings unrelated to RHD but yet relevant for future prognosis (i.e., bicuspid aortic valve, atrial-septal defect).Prospective clinical studies investigating the impact of secondary prevention for subclinical RHD on long-term clinical outcome will be of central relevance for future health resource utilization in developing countries.Keywords
Rheumatic Heart Disease, Cross-Sectional Survey, Echocardiographic Evaluation, WHO, School Children.- A Survey of Hyperdontia in Indian Children:250 Cases
Abstract Views :275 |
PDF Views:0
Authors
Affiliations
1 Koringa College of Pharmacy, Korangi-533 461, E.G. Dt., Andhra Pradesh, IN
1 Koringa College of Pharmacy, Korangi-533 461, E.G. Dt., Andhra Pradesh, IN