A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Vaidya, Ashok B.
- Drug Allergy in Practice
Authors
1 Department of Clinical Research, CIBA-GEIGY Research Centre, Bombay, IN
Source
The Indian Practitioner, Vol 29, No 7 (1976), Pagination: 433-441Abstract
No AbstractKeywords
No Keywords- Comparative Antioxidant Activity of Three Garlic Varieties:An in vitro Study
Authors
1 C. U. Shah College of Pharmacy, S.N.D.T Women’s University, Santacruz (West), Mumbai-400049, IN
2 C. U. Shah College of Pharmacy, S.N.D.T Women’s University, Mumbai-400 049, IN
3 ICMR Advanced Centre of Reverse Pharmacology in Traditional Medicine, Kasturba Health Society, Vile Parle (West), Mumbai- 400 056, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 3, No 4 (2011), Pagination: 162-165Abstract
The present paper discuss the antioxidant activity of methanol extracts of commonly available three garlic varieties in India using various in vitro methods Viz, DPPH assay, total reducing power and TBARS assay. The results were analyzed statistically by regression method and IC50 values were calculated for all the extracts. The amounts of total phenolics and flavonoids were also determined for each extract of garlic. All the extracts exhibited good free radical scavenging activity. Antilipid peroxidation activity of all garlic varieties was comparable to standard antioxidant, ascorbic acid. Methanol extract of single bulb variety of garlic exhibited better antioxidant activity among all three garlic varieties. The study provides evidence for the beneficial role of garlic. The antioxidant activity of garlic extracts will effectively contribute to the prevention of various chronic conditions and also confirms its ancient traditional claims.
Keywords
Garlic, Allium sativum, Antioxidant, Free Radical Scavenging.- Isolation and Quantitative Analysis of a Bioactive Polyphenol - Catechin in Anacardium occidentale Linn. (Leaves and Testa) by HPLC Analysis
Authors
1 C.U.Shah College of Pharmacy, S.N.D.T Women’s University, Mumbai-400049, IN
2 C. U. Shah College of Pharmacy, S.N.D.T. Women's University, Juhu Campus, Juhu Tara Road, Santacruz West, Mumbai-400 049, M.S., IN
3 ICMR Advanced Centre of Reverse Pharmacology in Traditional Medicine, Kasturba, Health Society, Vile Parle-(W), Mumbai-400 056, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 5 (2010), Pagination: 372-376Abstract
The present paper reports a method developed for isolation, characterization, structural elucidation and quantitative analysis of bioactive polyphenol - Catechin, from extracts of leaves and testa of Anacardium occidentale Linn (Cashew). Isolation of Catechin was carried out by Preparative TLC. The isolated Catechin was characterized by P-NMR, MS, IR spectroscopy and various chemical and chromatographic analysis. The method was established by using HPLC analysis and quantitation of isolated Catechin with marker Catechin. The purity of isolated Catechin was found to be 99.30% based upon the comparison of peak purity and peak areas of isolated Catechin and marker Catechin.
The HPLC separation system consisted of a C18 reversed-phase column, an isocratic elution system of methanol-water (9:1 v/v), and a UV-Visible detector with 254nm as the detection wavelength. The limit of detection (LOD) and limit of quantitation (LOQ) were found to be 0.2 μg and 0.6 μg respectively with an Rt value of 2.5 min.
The maximum amount of Catechin was found in aqueous extract of leaves (5.70%) and testa (13.65%).
Thus the developed HPLC method is rapid and simple technique for separation and determination of Catechin from extracts of A.occidentale leaves and testa. The method can be suitably applied for determination of Catechin from various plant extracts.
Keywords
Catechin, Anacardium occidentale Linn., Polyphenol, HPLC.- Relevance of Fast Track Integrative Approaches for the Control of COVID-19
Authors
1 Managing Director, Pharmanza Herbal Pvt. Ltd. Gujarat, IN
2 CEO, Synergia Life Sciences Pvt. Ltd. Mumbai, IN
3 Director, Division of Endocrine and Metabolic Disorders, Medical and Research Centre - Kasturba Health Society, Mumbai, IN
4 Research Director, Kasturba Health Society-Medical Research Centre, Mumbai, IN
Source
The Indian Practitioner, Vol 73, No 5 (2020), Pagination: 44-47Abstract
The current global pandemic of COVID-19 has spread over 212 countries with marked morbidity and substantial mortality. This has resulted in colossal burden on the worldwide healthcare system. Globally the management of this new disease is primarily supportive and resuscitative. Vaccine and anti-COVID-19 drugs are still under development. Oriental medicine of India and China and the medicinal plants offer a potential for a fast track development of phytopharmaceuticals. In the present overview we have shortlisted the following Indian medicinal plants, based on their traditional usage and scientific rationale: Phyllanthus amarus Schum and Thonn., Berberis aristata DC., Swertia chirata and Androgaphis paniculata (Burm. f.). These medicinal plants and the phytoactives can be rapidly evaluated for anti-COVID-19 activity through reverse pharmacology.Keywords
COVID-19, Reverse Pharmacology, Medicinal Plants, Antiviral Activity, Phytopharmaceuticals.References
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