Informatics Publishing Limited

K. Malathi ¹, Arjun Singh ¹

Affiliations
1 Periodontics, Government Dental college and Hospital, Tamil Nadu, IN

Abstract

The relationship between the periodontal health and the restoration of teeth is intimate and inseparable. Maintenance of gingival health constitutes one of the keys for tooth and dental restoration longevity. An adequate understanding of relationship between the periodontal tissue and restorative dentistry is essential to ensure adequate form and function of dentition and Esthetics and comfort to the patients. Restoration of fractured (traumatized), severely decayed, partially erupted (delayed passive eruption), worn or poorly restorated teeth is often difficult for the dentist without surgical and orthodontic intervention. Surgical crown lengthening of these teeth is necessary to provide adequate tooth structure for restoration or Esthetics enhancement, thus adhering to basic biological principles by preventing impingement on the periodontal attachment apparatus or biological width. Many clinicians have been unable to utilize the concept of biologic width in practical manner. Hence the purpose of this article is to describe the biologic width anatomy, evaluations & correction of its violation by different methods.

Keywords

Biologic Width, Crown Lengthening, Orthodontic Extrusion.

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Pallavi Shrirang Jamadagni ¹, Shrirang B. Jamadagni ¹, Arjun Singh ², Rajendra Kumar Singh ¹, Sachchidanand N. Upadhyay ¹, Sudesh N. Gaidhani ², Jayram Hazra ¹

Affiliations
1 Department of Pharmacology, Central Ayurveda Research Institute of Drug Development, CCRAS, Ministry of AYUSH, Kolkata - 700 091, West Bengal, IN
2 HQ, CCRAS, AYUSH, Janakpuri- 110058, New Delhi, IN

Abstract

Objectives: This study was conducted to estimate No Observed Effect Level (NOEL) or no observed adverse effect level of Swarna Bhasma an Ayurvedic classical preparation of gold in Wistar rats. Materials and Methods: Swarna Bhasma was prepared as per classical Ayurvedic text and analyzed for physicochemical properties. A total of 40 Wistar rats of either sex with an average body weight of 150-200 g were divided into four groups with 10 animals of both sexes in each group. Group I served as control and was given vehicle (Honey:Water in 2:3 ratio) Group II, III, IV were orally administered Swarna Bhasma @ 13.5, 6.75, 1.35 mg/kg body weight for 90 consecutive days. The effect of the drug was observed on ponderal changes, hematological, and biochemical parameters. At the end of the study, all animals were sacrificed and examined for gross pathological changes. Histopathological evaluation was performed only for control and high-dose group and of animals that were moribund sacrificed. Results: Swarna Bhasma was found to be safe at all levels tested. No significant treatment-related clinical signs were noted in all groups studied. The food and water consumption was not affected at highest given dose, i.e., 13.5 mg/kg body weight. No major alterations were observed during histopathological evaluation. Conclusion: This study indicates 13.5 mg/kg body weight as NOEL for Swarna Bhasma in Wistar rats.

Keywords

Ayurvedic Classical Drugs, Swarna Bhasma, Toxicity Study.

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Arjun Singh ¹, Pranaav S. Chandy ¹, Angad Singh ¹

Affiliations
1 Beroe Inc., IN

Abstract

The importance of assisting in building a strong social base for a better future and laying the foundation for a better society has gained attention from all aspects as well as corners in life. Corporate social responsibility is also one part of this attention.

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Amit Kumar ¹, Shri Krishna ², Arjun Singh ³

Affiliations
1 Regional Drugs Testing Laboratory, Government of India, Ministry of Health and Family Welfare, Chandigarh, IN
2 Department of Chemistry, Gurukula Kangari University, Haridwar, IN
3 Central Council of Research in Ayurveda and Sidha, Government of India, Ministry of Health and Family Welfare, Janakpuri, New Delhi, IN

Abstract

Present studies were carried out to screen Abutilon indicum Linn. (Malvaceae), for the point of view of its mineral analysis. The Plant had found throughout tropical and subtropical regions. The plant was mentioned in Indian Meteria medica which is commonly used in the indigenous system of medicine under the name "Atibala" in various ailments. The plant is used to treat various types of ailments and diseases such as neurological disorders, epistaxis and heart diseases as astringent, diuretic demulcent, in rheumatism and post delivery complaints in cattle. Leaves are used in toothache as demulcent, in gonorrhoea inflammation and wounds for stomachache, diabetes, diarrhoea, hydrococle Jaundice, boil, piles headache as a tonic in rheumatism and as an antipyretic agent. Elemental analysis indicated that plant had the sufficient presence of minerals. The nine elements Na, K, Ca, Mg, Fe, Cu, Co, Mn and Ni were determined in all parts of plant ash. The present investigation of mineral elements was carried out using AAS&ICP techniques. While some physico-chemical parameters viz. physical state, colour, taste, total ash content, ash value (water, acid and alcohol soluble), pH and moisture content were also studied. It showed the presence of different minerals, which can be suggested for therapeutic efficacy and vitality as dietary supplement.

Keywords

Abutilon indicum Linn, Mineral Elements, AAS, ICP, Dietary Supplements.

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Arjun Singh ¹, Ajay Kr. Meena ², M. M. Rao ², Sudeep Mishra ¹, M. M. Padhi ¹, Ramesh Babu ¹

Affiliations
1 Central Council for Research in Ayurveda and Siddha, Janakpuri, Delhi-110058, IN
2 National Institute of Ayurvedic Pharmaceutical Research, Patiala - 47001, Punjab, IN

Abstract

Herbal drugs are traditionally used in various parts of the world to cure different diseases. The present study has been conducted to evaluate the quality control parameters of the hydro alcoholic extracts of Tephrosia purpurea Linn ;an important Indian medicinal plant widely used in the preparation of Ayurvedic formulations. Tephrosia purpurea Linn. is a highly branched, sub-erect herb commonly known in Sanskrit as Sharapunkha. It has been used in Indian traditional medicine for the treatment of various inflammatory disorders. The plant is used to cure diseases of the kidney, liver, spleen, heart, blood, skin eruptions, bronchitis, bilious febrile attack, boils, pimples, and bleeding piles. The dried herb is effective as a tonic, laxative, and diuretic. The ischolar_mains and seeds are have insecticidal, piscicidal and vermifugal properties.

As there is no detailed standardisation work reported on Tephrosia purpurea Linn extract, the physicochemical parameters, phytochemical analysis, toxic heavy metals and microbial contamination analysis are carried out. The study revealed specific identities for the particular crude drug which will be useful in identification and control to adulterations of the raw drug and Ayurvedic formulations.

Keywords

Tephrosia purpurea Linn, Ayurvedic, Physicochemical Parameters, Toxic Metals.

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Ajay Kumar Meena ¹, Uttam Singh ², Arjun Singh ³, Sudeep Mishra ³, M. M. Rao ¹, M. M. Padhi ³, Ramesh Babu ³, A. Gaurav ²

Affiliations
1 National Institute of Ayurvedic Pharmaceutical Research, Patiala- 147001, Punjab, IN
2 School of Pharmaceutical Sciences, Shobhit University, Meerut, UP, IN
3 Central Council for Research in Ayurveda and Siddha (CCRAS), Janakpuri, Delhi-110058, IN

Abstract

Vitex negundo Linn (Five-leaved chaste tree), Hindi-Nirgundi, Sanskrit-Sindhuvara, Tamil and Malyalam-Vennochi, Telugu-Nalla vavili and Punjabi-Marwan (Family: Verbenaceae), is an important medicinal plant found throughout India. All parts of this plant especially the leaf and ischolar_main extracts are being used in various formulations in Ayurveda and Unani systems of medicine. Vitex negundo Linn is pungent, bitter and astringent in taste and according to Ayurveda , it alleviates vata and kapha doshas, but aggravates pitta dosha. It possesses light and dry attributes. Its leaves and seeds are widely used externally for rheumatism and inflammations of joints and also reported to have insecticidal properties. Internally, decoction of its leaves is taken as diuretic, expectorant, vermifuge, tonic and febrifuge. The chemical components of the essential oil of leaf isolated from the plant are used to treat colds and coughing spells. Vitex negundo Linn is used in Classical Ayurvedic Preparations like Nirgundi kalka, Nirgundi ghrta, Nirgundi kvatha, Vranasodhana taila, Visagarbha taila etc. The evaluation studies of Pharmacopoeial standards, phytochemical parameters suggested that the observed physiochemical parameters are of great value in quality control and formulation development of Vitex negundo Linn. Physicochemical parameters like preliminary characteristics, toxic heavy metals, and aflatoxin analysis were carried out. The study revealed that the results on different parameters of the crude drug will be useful in identification and control of adulterations.

Keywords

Ayurveda, Vitex negundo Linn, Toxic Metals, Aflatoxin and Quality Control.

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Arjun Singh ¹, Saumya Ranjan Jena ¹, Bhupati B. Mishra ¹

Affiliations
1 Department of Mathematics, School of Applied Sciences, KIIT University, Bhubaneswar – 751024, Odisha, IN

Abstract

In recent years mixed quadrature rule for analytic functions has been utilized in the field of Science and Technology. A mixed quadrature rule for degree of precision eleven has been established by taking two constituent rules each of degree of precision nine. The proposed mixed quadrature rule has been tested on different functions and comparable with different authors to find the best approximate solution to the exact results. Mixed quadrature rule on analytic function is applied in the field of adaptive quadrature which is essential in the physical sciences.

Keywords

Analytic Functions, Degree of Precision, Maclaurin’s Theorem, Mixed Quadrature, Richardson Extrapolation MSC 2010: 65D30, 65D32

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Saurabh Mishra ¹, Arjun Singh ¹, Satyam Gupta ¹

Affiliations
1 Department of Electronics and Communication Engineering, Invertis University, Bareilly, IN

Abstract

Wireless Sensor Networks (WSNs) have faced major challenges in security. The sensor nodes are deployed in non controlled environment, facing the danger of information leakage, adversary attacks and other threats. Trust and Reputation models are required to solve this problem and to identify malicious, selfish and compromised nodes. However, Cryptography is the traditional approach to provide network security through borrowing tools and mechanisms. Reputation-based frameworks, where nodes maintain reputation of other nodes and use it to evaluate their trustworthiness are deployed to provide scalable, diverse and generalized approach to counter misbehaviors resulting from malicious and selfish nodes in the networks. This paper aims to feature of the role and importance of security aspects in Wireless Sensor Networks (WSNs). An attempt has been made for the same by comparing some important trust and reputation models that are purely dedicated to protect the WSNs from adversary attacks and maintain the security issues. The comparison has been made with respect to accuracy and path length and founded that modified reputation models give the best accuracy in different wireless sensing modes as compared to other reputation models. Additionally, it consumes lesser path length and resources in oscillating and collusive environments.

Keywords

WSNs, Security Threats, Trust and Reputation Models (TRMs), Malicious Nodes, Cryptography.

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M. Prem Blaisie Rajula ¹, Malathi Subramanioum ², Muthukumaraswamy ², Arjun Singh ³

Affiliations
1 SRM Kattankulathur Dental College & Hospital, Chennai, IN
2 Tamil Nadu Government Dental College & Hospital, Chennai, IN
3 Post Graduate Student, Tamil Nadu Government Dental College & Hospital, Chennai, IN

Abstract

Background: Platelet-Rich Fibrin (PRF), the second-generation platelet concentrate has various fringe benefits over other platelet concentrates. Just finite number of research works have concentrated on the utilization of PRF in combination with various kinds of bone grafts in intra-bony defects. Objective: The primary intention of this study was to determine the clinical and radiographical efficacy of Bioactive-glass with and without autologous PRF in the management of three-wall vertical defects. Methods: Twenty intrabony defects were arbitrarily chosen and treated either with Bioactive Glass (BG) alone or in mix with PRF (PRF/BG). Clinical parameters were documented preoperatively (baseline) and at six months post-operatively. Radiographic analysis was performed at baseline, third and sixth-month intervals. Results: The study outcome demonstrated that both treatment approaches were effectual. Significant decrease in the mean probing depth and gain in clinical attachment was observed in BG+PRF and BG groups as compared to baseline but was statistically insignificant at 6 months. (p=0.475, p=0.245 respectively). Radiographically, reduction in defect depth was significantly greater in BG+PRF group than BG group (p=0.007) at 6 months. Conclusion: Within the limitation of the current study, it is proposed that both treatment modalities are effective in the management of 3-wall intra-bony defects. The outcomes additionally uncovered that incorporation of PRF with BG has more successful and promising results. Hence in future, clinical trials with bigger sample size may be employed to further explore the potential benefits of PRF as a sole grafting material.

Keywords

Blood Platelets, Glass, Intrabony, Regeneration.

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Arjun Singh ¹

Affiliations
1 Political Science, Guru Nanak Dev University College, Sujanpur, Punjab, IN

Abstract

Rajasthan the largest state of India is located in the west of the country, near the border with Pakistan. It covers 10 per cent of the country's area. The population of the state is approaching to 70 million people. The latitude of Rajasthan is 27.391277 and the longitude is 73.432617. It came into existence on 30 March 1949 as a result of the integration of 22 princely states. It faces major hindrance in economic development that is poverty which  tend to perpetuate low level of development in the region. This is due to politicians, who hold the power equation over the years but haven’t  took any solid initiative to curb poverty in the state. As a matter fact the hostile atmosphere conditions prevailing in the state have proved a potent blockade for economic growth and development. But in the present scenario Vasundhra Government has made some serious efforts towards economic development of the state. This paper is an attempt to understand current political vision and efforts of present Government for economic development of Rajasthan. A thorough research study regarding political influence and its role over economic development of Rajasthan has elicited many hidden issues of economic development  who’s answer lies in political approach. The study has tried its best to present the problems of economic development in the Rajasthan due to political business and has also suggested ways to overcome development problems of the state.

Keywords

Perpetuate, Aspirations, Fostering, Prominence, Anti-Incumbency, Thumping, Lacklustre, Confederation, Apprenticeship, Supersedes, Reinventing.

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Cheemalapati Venkata Narasimhaji ¹, A. K. Meena ¹, B. Maheshwari ¹, Arjun Singh ², Ravindra Singh ², R. Ilavarasan ¹

Affiliations
1 Captain Srinivasa Murthy Regional Ayurveda Drug Development Institute, A. A. Hospital Campus, Arumbakkam, Chennai - 600106, IN
2 Central Council for Research in Ayurvedic Science, Janakpuri, Ministry of AYUSH, New Delhi - 110058, IN

Abstract

The present study was carried out for evaluation of TLC fingerprint profiles of volatile oils/essential oils of the each ingredient of the polyherbal formulation of Trikatu churna and comparison of the volatile oil of the finished product or formulation as such. Essential oils/volatile oil contents are characteristic to the ingredients or raw botanicals to identify them easily. In the raw botanicals, where ever its presence is possible and its verification through the TLC/HPTLC fingerprint profile is the one of the best ways to identify and evaluate the quality of the finished formulation in the course of development of a standardization protocol as a quality control tool.

Keywords

Volatile Oil, HPTLC, Fingerprint Profile, Poly Herbal Formulation, Standardization and Quality Control.

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Amit Kumar ¹, Sonia Setia ², Arjun Singh ³, Thomas Abraham ⁴, Yashaswi Shakya ⁴

Affiliations
1 Assistant Professor, Sharda University, Greater Noida, Uttar Pradesh,, IN
2 Assistant Professor, Sharda University, Uttar Pradesh, Greater Noida,, IN
3 Student, Sharda University, Greater Noida, Uttar Pradesh,, IN
4 Sharda University, Greater Noida, Uttar Pradesh,, IN

Abstract

Our work systematically analyze the sentiment of product reviews and evaluate the correlation with their corresponding ratings.Sentiment analysis identifies the positive or negative mood represented in a piece of literature. Consumers write reviews withprecise ratings on e-commerce platforms such as Amazon. We’ve noticed that there are occasionally discrepancies between thereview and the rating. We performed deep learning guided sentiment analysis to identify such mismatches from amazon productreview data. We convert reviews to vectors using paragraph vector and use them to develop a neural network using a GRU orgated recurrent unit our perspective makes advantage of both the semantic link between review content and product information.

Keywords

Sentiment Analysis, RNN, SVM, GRU.

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Arjun Singh ¹

Affiliations
1 Department of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, US

Abstract

Traditional medicine is a body of knowledge, skills, and practices based on traditional cultures' presumptions, beliefs, and experiences in order to maintain their health. Traditional herbal treatments are highly valued among many rural or indigenous people in many underdeveloped nations. According to the World Health Organization, about 80% of the world's population relies on traditional medicine, with 60% of rural Indians using herbal treatments. During the previous five years, utilization of herbal supplements grew from 2.5% to 12 percent. The assessment of novel medications, particularly phytochemically derived materials, has opened up a large arena for study and has aided India's shift from traditional to modern medicine. Tannins, alkaloids, carbohydrates, terpenoids, steroids, flavonoids, and phenols are some of the chemical components found in medicinal plants that have a distinct physiological effect on the human body. Medicinal plants do not only exhibit natural therapeutic properties, but also provide natural prevention against various diseases. As a result, we are attempting to summarize, gather the number of plants, and their ethnopharmacological qualities in this complete review study research.

Keywords

Traditional Medicine, Herbal Medicine, Ethnopharmacological, Phytochemicals, Medicinal Plants

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