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Sahu, Archana
- Importance of the Oxidation Reaction of Sodium Metaperiodate for Spectrophotometric Assay of Reserpine
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Authors
D. K. Singh
1,
Archana Sahu
1
Affiliations
1 Department of Chemistry, H. B. Technological Institute, Kanpur-208 002, IN
1 Department of Chemistry, H. B. Technological Institute, Kanpur-208 002, IN
Source
Scientia Pharmaceutica, Vol 72, No 2 (2004), Pagination: 121-129Abstract
A new simple, accurate and reasonably sensitive spectrophotometric method is described for the determination of reserpine based on the oxidation with sodium metaperiodate in the presence of acetic acid and coupling with 3-methyl-2-benzo thiazolinone hydazone hydrochloride (MBTH) to form highly blue coloured product showing maximum absorbance at 630 nm. Beer's law is obeyed in the range 0.2-1.6 μg ml-1. The relative standard deviation was found to be less than 1%. The proposed method can be applied for the estimation of reserpine in tablets with no evidence of interference from excipients.Keywords
Reserpine; Spectrophotometry; Sodium Metaperiodate; 3-Methyl-2-Benzo Thiazolinone Hydrazone Hydrochloride.
References
- Katzung B G, In: Farmacologia Basica e Clinica. 5th ed. Guanabara Koogan, Rio de Janeiro. 1994:114.
- Goldman L S, Gilman A, In: The Pharmacological Basis of Therapeutics. 4th ed., Macmillan, New York, 1970
- Varma S R, Calatatud J M, Mottola H A. Continuous Flow Determination of Reserpine by Oxidation with Periodate Ion and Catalysis by Manganese Dioxide Reactor. Anal. Chim. Acta, 1990; 233: 235-241.
- Manzar A, Qazi N, Hussein I, Azhar I. Spectrophotometric Determination of Some Indole Drugs. J. Chem. Soc. Pak. 2000; 22:111-114.
- Blazneavskii N E, Batalov A I. Oxidimetric Determination of Alkaloids Based on the N-oxidation with Peroxycarboxylic acid. J. Anal. Chem. 1999; 54: 78-80.
- Wang J, Ozsoz M. Hydrophobic Stripping Voltametry of Antihypertensive Drugs at Lipid Modified Electrodes. Analyst 1990; 115: 831-834.
- Miguel S, Sanchez-Aibar Juan J. Spectrofluorometric Determination of Reserpine by Oxidation with Cerium (IV) Sulphate. Analyst 1996; 121: 1581-1582.
- Cieri Ugo R. Determination of Reserpine and Chlorothiazide in Commercial Tablets by LC with Fluorescence and UV Absorbance Detector in Series. J. AoAc Int. 1995; 78:1384-1387.
- Yakimov S A, Tuzova T P, Kuzovkina I N, Wulfson A N, Miroshnikov A I. Determination of lndole Alkaloids from R. Serpentina and R. Vomitoria by HPTLC and HPLC. J. Chromatogr A 1995; 704: 357-362.
- Ke Jing, Yancey M, Zhang S, Lowes S, Henion J. Quantitative Liquid Chromatographic Tendam Mass Spectrometric Determination of Reserpine in FVB/N Mouse Plasma Using a Chelating Agent (disodium EDTA) for Releasing Protein Bonded Analytes During 96 Well Liquid-Liquid Extraction. J. Chromatogr A 2000; 742: 369-380.
- Disimone L, Portelli G, Del Giudice M R, Gatta F, Settimj G. Application of a New Method for the Determination of Reserpine and Rescinnamine to the Control of Chemical Drugs. Farmaco 1980; 35: 223-232.
- Aucelio R Q. Campiglia A D. Solid Surface Room Temperature Phosphometry Analysis of Reserpine in Pharmaceutical Formulations. Talanta 1994; 41: 2131-2136.
- Arruda A F, Aucelio R Q. Room Temperature Phosphometry for the Selective Determination of Yohimbine in Presence of Reserpine like lndolic Alkaloids. Anal. Sci. 2002; 18: 831-834.
- Qiao-Hua W, Huisheng Z, Qiang er W, Guo-War C. New Flow Injection Chemiluminescence's System for the Determination of Reserpine. Fenxi Kexue Xuebao 2001; 17: 501-504.
- Taira A, Smith D E. Diffential Pulse and ac Polarography of Reserpine Using Aprotic Organic Solvent System. J. Assoc. Off. Anal. Chem. 1978; 61: 941-948.
- Spiegel M R. In: Theory and Problems of Probability and Statistics: Mc Graw-Hill. New York, 1975: 215.
- British Pharmacopoeia, H. M. Stationary office, London, 2000.