Informatics Publishing Limited

T. Arun ¹, Arangannal Ponnudurai ², J. Jeevarathan ³, M. Vijayakumar ⁴, S. Amudha ⁵, J. Aarthi ⁵

Affiliations
1 Post Graduate Student, Department of Pedodontics, Sree Balaji Dental College, BIHER, Pallikarani, Chennai, IN
2 Professor and Head of the Department, Sree Balaji Dental College, BIHER, Pallikarani, Chennai, IN
3 Professor, Sree Balaji Dental College, BIHER, Pallikarani, Chennai, IN
4 Senior Lecturer, Sree Balaji Dental College, BIHER, Pallikarani, Chennai, IN
5 Reader, Sree Balaji Dental College, BIHER, Pallikarani, Chennai, IN

Abstract

Mesenchymal Stem cells-have been considered a promising tool for tissue repair and regeneration. Different sources of mesenchymal stem cells may differ in their biological characteristics and clinical applications. This short communication gives an over view about the isolation, characterization, multi lineage and proliferation capacity of mesenchymal stem cells from umbilical cord and stem cells from human exfoliated deciduous teeth (SHED).The differences may be associated with different levels of cytokines, growth factors, surface markers, fibroblast growth factors, vascular endothelial growth factor expression and receptor activity.

Keywords

Mesenchymal Stem Cells, Dental Stem Cells, Umbilical Cord Stem Cells, Stem Cells from Human Exfoliated Deciduous Teeth.

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R. Ishwarya ¹, J. Aarthi ², Arangannal Ponnudurai ³, J. Jeevarathan ⁴, S. Amudha ⁵, M. Vijayakumar ⁵

Affiliations
1 Post Graduate Student, Department of Pedodontics, Sree Balaji Dental College, BIHER, Pallikarani, Chennai, IN
2 Reader, Department of Pedodontics, Sree Balaji Dental College, BIHER, Pallikarani, Chennai, IN
3 Professor and Head of the Department, Sree Balaji Dental College, BIHER, Pallikarani, Chennai, IN
4 Professor, Sree Balaji Dental College, BIHER, Pallikarani, Chennai, IN
5 Reader, Sree Balaji Dental College, BIHER, Pallikarani, Chennai, IN

Abstract

Over the years several products have been proposed and testified as pulpotomy medicaments for primary teeth. Formocresol has been considered as gold standard for this procedure. Despite its clinical success, the use of formocresol has declined due to its apparent mutagenic and carcinogenic property. Controversies regarding the use of formocresol has urged the researchers to constantly pursuit for a promising alternative. Phytotherapy has been a recent trend. The aim of this paper is to analyse the existing literature on the various pulpotomy medicaments available for primary teeth and the evolution of natural products for the same.

Keywords

Pulpotomy Medicaments, Formocresol, Controversies, Phytotheraphy.

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M. Madhumitha ¹, M. Vijayakumar ², Arangannal Ponnudurai ³, J. Jeevarathan ⁴, J. Aarthi ⁵

Affiliations
1 Post Graduate Student, Department of Paedodontics, Sree Balaji Dental College, BIHER, Pallikarani, Chennai, IN
2 Senior Lecturer, Sree Balaji Dental College, BIHER, Pallikarani, Chennai, IN
3 Professor and Head of the Department, Sree Balaji Dental College, BIHER, Pallikarani, Chennai, IN
4 Professor, Sree Balaji Dental College, BIHER, Pallikarani, Chennai, IN
5 Reader, Sree Balaji Dental College, BIHER, Pallikarani, Chennai, IN

Abstract

Background: Dental caries is an infectious microbiologic disease of the teeth and is one of the most common diseases in humans. It is a multifactorial disease caused by interaction between four principal factors-the host (saliva and teeth), the microflora, the substrate (diet) and the time. Targeting the microbial factor of the disease, researchers have been developing vaccination to protect the caries prone children and adults. Immunization includes active and passive immunization. Vaccines should be safe and effective. This article gives an insight into the shortcomings and challenges of caries vaccinations.

Keywords

Caries Vaccination, Active Immunization, Passive Immunization.

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