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Patil, Aniket
- Preparation and Evaluation of Fast Dissolving Tablet Tramadol Hydrochloride
Abstract Views :163 |
PDF Views:4
Authors
Rohan Patil
1,
Neha Patil
1,
Aniket Patil
1,
S. J. Shid
1,
V. N. Dange
1,
C. S. Magdum
1,
S. K. Mohite
1
Affiliations
1 Department of Pharmaceutics, Rajarambapu College of Pharmacy, Kasegaon, Tal-Walwa, Dist-Satara, IN
1 Department of Pharmaceutics, Rajarambapu College of Pharmacy, Kasegaon, Tal-Walwa, Dist-Satara, IN
Source
Asian Journal of Pharmacy and Technology, Vol 6, No 3 (2016), Pagination: 183-185Abstract
Novel drug delivery system assists to achieve better patient compliance. Fast dissolving tablets are one of them. FDT have benefits such as accurate dosing, easy portability and manufacturing, good physical and chemical stability and an ideal alternative for pediatric and geriatric patients. FDDT formulation combines the advantage of both liquid and conventional tablet formulation while also offering advantage over both traditional dosage forms. This review gives a view of advantages, limitations, need for formulating FDTS, Formulation factors, excipients used, and methodology and evaluation parameters.
Fast dissolving tablets (FDTs) can be prepared by different methods, such as direct compression, freeze-drying, spray drying, sublimation, wet granulation method4. The basic approach for the development of FDTs is the use of superdisintegrants. The aim of this study was to formulate FDTs with sufficient mechanical integrity and to achieve faster disintegration in the oral cavity without water. To achieve this goal, mannitol used as diluent as well as sweetening agent for the formulation of tablets. Attempts were made to enhance dissolution rate along with faster disintegration using superdisintegrants, like microcrystalline cellulose. Tramadol hydrochloride, a centrally acting synthetic opioid analgesic, was selected as the active pharmaceutical ingredient in the study.
Keywords
Tramadol Hydrochloride, Direct Compression Method, Microcrystalline Cellulose.
- Graphene Quantum Dots: A Pharmaceutical Review
Abstract Views :146 |
PDF Views:0
Authors
Affiliations
1 Department of Pharmaceutics, Ashokrao Mane Institute of Pharmaceutical Sciences and Research, Save Maharashtra, 416213, IN
2 Department of Pharmaceutics, Bharati Vidyapeeth College of Pharmacy, Kolhapur, Maharashtra, 416013 Department of Pharmaceutical Chemistry, Y.D. Mane Institute of Pharmacy Kagal, IN
1 Department of Pharmaceutics, Ashokrao Mane Institute of Pharmaceutical Sciences and Research, Save Maharashtra, 416213, IN
2 Department of Pharmaceutics, Bharati Vidyapeeth College of Pharmacy, Kolhapur, Maharashtra, 416013 Department of Pharmaceutical Chemistry, Y.D. Mane Institute of Pharmacy Kagal, IN
Source
Asian Journal of Pharmaceutical Research, Vol 12, No 4 (2022), Pagination: 341 - 348Abstract
Quantum dots (QDs) possess exclusive physicochemical and optical properties which are suitable for devices like, optoelectronic devices, light-emitting diodes, and photovoltaic cells. Compared to the selenium and tellurium/metasulfide- based QDs, graphene quantum dots (GQDs) are less toxic and have more biocompatibility, these properties make them ideal candidates for the application in various fields like, drug delivery agents, bio-imaging, therapeutics, and theranostics. Different types of methods for the synthesis of GQDs like top-down and bottom-up methods are systematically deliberated in this study. Different physicochemical, optical, and biological properties are included in this particular text. These properties include size- and chemical-composition-dependent fluorescence, therapeutics, cellular toxicity, disease diagnostics, and biocompatibility. At last, predictions and possible directions of GQDs in drug delivery and bioimaging systems are deliberated concerning challenges such as synthesis, biocompatibility, and cellular toxicity.
Keywords
Bioimaging, Graphene Quantum Dots, Nanostructured graphene, Optical properties, Photoluminescence, Quantum dotsReferences
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