Informatics Publishing Limited

Y. S. Tanwar , Amit Kumar Jain

Abstract

The present research has been undertaken with the aim to develop a topical gel formulation of Diclofenac sodium using different gelling agent carbopol, Na CMC, HPMC (K4M) and sodium alginate in different concentration, which would attenuate the gastrointestinal relater toxicities associated with oral administration. They were evaluated for physicochemical properties such as homogeneity, grittiness, viscosity, pH, Spreadability, drug content, skin irritancy , in vitro drug release, stability studies. The in vitro drug release rate of gel was evaluated using Franz diffusion cell containing cellophane membrane with phosphate buffer pH 6.8 as the recept or medium. Studies showed that drug release was decrease with increase in gelling agent concentration because polymer concentration increases, viscosity increases. Drug was absorbed from site of application as long as it remains in higher concentration gelling agent in solution form.

Keywords

Diclofenac Sodium, Carbopol, Hydroxyl Propyl Methyl Cellulose, Sodium Alginate Anti - Inflammatory Activity.

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Amit Kumar Jain ¹, Aashish Khaira ¹, Amit Suhane ¹

Affiliations
1 Department of Mechanical Engineering, M.A.N.I.T., Bhopal, IN

Abstract

This paper illustrates how an effective implementation of NDT (Non Destructive testing) could influence the productivity and profitability of a manufacturing process. It was possible to show how changes in the productivity affect profit, separately from the effects of changes in the uncontrollable factors, i.e. price recovery. NDT is not a cost centre, but a profit generating function. Markets are affected by diverse customer needs, which demand higher quality, shorter delivery time, higher customer service level and lower prices. At the same time, product life cycles are becoming shorter and shorter. Success in any competitive context depends on having either a cost advantage or a value advantage, or, ideally, both. So involvement of new and effective technology in companies working is required, NDT is one of them.

Keywords

Non Destructive Testing, Maintenance, Non Destructive Techniques, Cost Effective Maintenance, Efficiency, Effectiveness, Productivity, Profitability.

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Amit Kumar Jain ¹, Usha ¹, Bhalendra Singh Rajput ¹

Affiliations
1 Rani Lakshmi Bai Central Agricultural University, Jhansi (U.P.), IN

Abstract

Computer technology in agriculture field : Agriculture is a most common occupation in India. More than 50 per cent people lived in villages and the most of the family depends on the agriculture. Indian GDP also depend on agriculture so as agriculture will grow as well as Indian GDP also grow. Todays are computer world as well as day passes new technology also introduce. So use of computer technologies in Agriculture are most important for the farmers. Many of the agriculture equipment's, machines and farmers tools fully programmed by the Computer PCBs.

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