Refine your search
Collections
Co-Authors
Year
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Murugesan, Ambika
- Cytomorphometric Analysis of Exfoliative Cytology in Buccal Mucosa of Smokers and Non Smokers in Diabetic Patients in Salem Population – A Comparative Study
Abstract Views :166 |
PDF Views:0
Authors
Affiliations
1 Department of Oral Pathology, Vinayaka Mission’s Sankarachariyar Dental College, Vinayaka Mission’s Research Foundation (Deemed to be University), Ariyanur - 636308, Salem, Tamil Nadu, IN
2 Professor, Department of Oral Pathology, Vinayaka Mission’s Sankarachariyar Dental College, Vinayaka Mission’s Research Foundation (Deemed to be University), Ariyanur - 636308, Salem, Tamil Nadu, IN
1 Department of Oral Pathology, Vinayaka Mission’s Sankarachariyar Dental College, Vinayaka Mission’s Research Foundation (Deemed to be University), Ariyanur - 636308, Salem, Tamil Nadu, IN
2 Professor, Department of Oral Pathology, Vinayaka Mission’s Sankarachariyar Dental College, Vinayaka Mission’s Research Foundation (Deemed to be University), Ariyanur - 636308, Salem, Tamil Nadu, IN
Source
Journal of Pierre Fauchard Academy (India Section), Vol 34, No 4 (2020), Pagination: 107-112Abstract
Introduction: Altered cellular microenvironment of oral cavity is a not an uncommon finding in diabetes mellitus patients. Environmental factors also play a pivotal role in cellular changes where tobacco smoking is one of the major risk factor. Aim & Objective: The aim of the study is to find the cytological changes in oral mucosal cells of diabetic people with and without smoking by using cytomorphometric analysis. Materials and Methods: Oral smears were taken from 50 diabetic patients where 25 with smoking habit and 25 without smoking habit from the oral pathology department of Vinayaka mission’s Sankarachariyar dental college and hospital. The smears were fixed with 95%ethyl alcohol and stained with hematoxylin and eosin stain. The stained section observed under image analyzer for cytomorphometric analysis. Results: Cellular and nuclear alterations was significantly increased in diabetic patients with smoking habit when compared to diabetic patients without smoking, with a significant P value of 0.001. Conclusion: Diabetes mellitus influences a definite changes in cellular microenvironment in oral mucosa of smokers. However, further research is required to analyze the significance of these findings as a tool for identifying precancerous condition of oral tissues at an early stage.Keywords
Buccal Mucosa, Cytomorphometric Analysis, Diabetic Patients, H&E Staining, Non-smokers, Oral Exfoliative Cytology, Smokers
References
- Avanindra Kumar, Avanish Kumar, Ritu, Sufia Parveen, Md. Jawed Akhtar. “Clinopathological and Cytological Changes in Oral Mucosa of Patients having Tobacco Smoking Habbit”. Journal of Evolution of Medical and Dental Sciences. 2014; 3(66): 14250–14256.
- Tandon A, Bordoloi B, Jaiswal R, Srivastava A, Singh RB, Shafique U. Demographic and clinicopathological profile of oral squamous cell carcinoma patients of North India: A retrospective institutional study. SRM Journal of Research in dental sciences. 2018; 9: 114–8.
- Fatemeh Ahmadi-Motamayel, Parisa Falsafi, Zahra Hayati, Farzad Rezaei and Jalal Poorolajal. Prevalence of Oral Mucosal Lesions in Male Smokers and Non-smokers. Chonnam Medical Journal. 2013; 49: 65–68.
- Gianluca Tenore, Alessandro Nuvoli, Ahmed Mohsen, Andrea Cassoni, Andrea Battisti, Valentina Terenzi et al. Tobacco, Alcohol and Family History of Cancer as Risk Factors of Oral Squamous Cell Carcinoma: Case-Control Retrospective Study. MDPI, 2020; 10 (3896): 1–11.
- Jay O. Boyle, Zeynep H. Gümüş, Ashutosh Kacker, Vishal L. Choksi, Jennifer M. Bocker, Xi Kathy Zhou, Rhonda K. Yantiss, Duncan B. Hughes et al. Effects of Cigarette Smoke on the Human Oral Mucosal Transcriptome. American Association of Cancer Research. 2010; 3(3): 266–278.
- Parmar D, Sawke G K, Sawke N. A cytomorphometric Evaluation of the Oral Mucosal Cells in Type II Diabetics. People’s Journal of Scientific Research. 2014; 7(2): 22–27.
- Alliny de Souza Bastos, Andressa Rosa Perin Leite, Rubens Spin-Neto, Patrıcia Oehlmeyer Nassar, Elaine Maria Sgavioli Massucato, Silvana Regina Perez Orrico. Diabetes mellitus and oral mucosa alterations: Prevalence and risk factors. Elsevier. 2011; 100–105.
- Rajesh P. Dikshit, K. Ramadas, Mia Hashibe, Gigi Thomas, Thara Somanathan and R. Sankaranarayanan. Association between diabetes mellitus and pre-malignant oral diseases: A cross sectional study in Kerala, India. International Agency for Research on Cancer. 2006; 118: 453–457.
- Renuka Verma, Anil Singh, Manjunath Badni, Akhilesh Chandra, Shalini Gupta, and Ruchita Verma. Evaluation of exfoliative cytology in the diagnosis of oral premalignant and malignant lesions: A cytomorphometric analysis. Dental Research Journal. 2015; 12(1): 83–88.
- Nandita KP, Boaz K, Srikant N, Lewis AJ, Manaktala N. Oral epithelium in diabetics: A cytomorphometric correlation. Dent Hypotheses. 2014; 5(2): 59–65.
- Anthony S Fauci, M.D. Harrison’s Principles of Internal Medicine. 17th ed. Vol. II. McGraw-Hill Professional Publishing. 2008.
- Ogden GR, Cowpe JG, Green MW. Quantitative exfoliative cytology of normal buccal mucosa: Effect of smoking. J Oral Pathol Med. 1990; 19: 53–5.
- Goregen M, Akgul HM, Gundoğdu C; The cytomorphological analysis of buccal mucosa cells in smokers; Turk J Med Sci. 2011; 41 (2):205–210.
- Seifi S, Feizi F, Mehdizadeh M, Khafri S, Ahmadi B; Evaluation of Cytological Alterations of Oral Mucosa in Smokers and Waterpipe Users; CELL JOURNAL (Yakhteh). 2014; 15 (4): 302–09.
- Alberti S, Spadella CT, Francischone TR, Assis GF, Cestari TM, Taveira LA. Exfoliative cytology of the oral mucosa in type II diabetic patients: morphology and cytomorphometry. J Oral Pathol Med. 2003; 32: 538–43.
- Jajarm HH, Mohtasham N, Moshaverinia M, Rangiani A. Evaluation of oral mucosa epithelium in type II diabetic patients by an exfoliative cytology method. J Oral Sci. 2008; 3: 335–40.
- Shareef BT, Ang KT, Naik VR. Qualitative and Quantitative Exfoliative Cytology of Normal Oral Mucosa in type II Diabetic patients. Med Oral Patol Oral Cir Bucal. 2008; 13: 693–6.
- Tozoglu U, Bilge OM. Exfoliative cytology of type I diabetic patients. Eur J Gen Med. 2010; 7: 264–8.
- Prasad H, Ramesh V, Balamurali P. Morphologic and cytomorphometric analysis of exfoliated buccal mucosal cells in diabetes patients. J Cytol. 2010; 27: 113–7.
- Suvarna M, Anuradha C, Kumar KK, Sekhar PC, Chandra KLP, Reddy BVM. Cytomorphometric analysis of exfoliative buccal cells in type II diabetic patients. J NTR Univ Health Sci. 2013; 1:33–7.