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Ganjare, A. B.
- Evaluation of Antioxidant Activity of the Aerial Parts of the Abutilon Indicum (linn) Sweet (Malvaceae)
Authors
1 Department of Pharmacognosy, S. N. D. College of Pharmacy, Yeola, A/P- Babhulgaon, Tal - Yeola, Dist-Nasik, Pin- 423401, Maharashtra, IN
2 Department of Pharmacology, S. N. D. College of Pharmacy, Yeola, (M. S.), IN
3 Department of Pharmacognosy, Pravara Rural College of Pharmacy, Loni, (M. S.), IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 2, No 5 (2010), Pagination: 324-327Abstract
Abutilon indicum (Linn) sweet (Malvaceae) is a weed found on way side and at west place throughout the India, commonly known as Atibala. Phytochemical study of the plant revealed that the plant contains various phytoconstituent like flavonoids, tannins and phenolic compounds. Plant may give antioxidant activity as these phytoconstituents are reported to have antioxidant potential. Antioxidant activity of the various extracts of the aerial parts of A. indicum viz. petroleum ether extract, chloroform extract, methanol extract and aqueous extract was evaluated by using DPPH assay method, ABTS assay method and FRAP assay method. Total phenolic content of all the extracts was also determined. Results showed that methanol extract shows potent antioxidant activity and highest phenolic content.Keywords
Abutilon indicum, DPPH Assay, ABTS Assay, FRAP Assay, Total Phenolic Content.References
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Authors
1 Department of Pharmacognosy, Pravara Rural College of Pharmacy, Pravaranagar, A/P- Loni, Tal -Rahata, Dist- Ahmednagar, Pin- 413736, Maharashtra, IN
2 Dep. of Pharmacognosy, Pravara Rural College of Pharmacy, Pravaranagar, IN
3 Dep. of Pharmacology, Pravara Rural College of Pharmacy, Pravaranagar, IN
4 Deparrment of Pharmacognosy, M.M. College of Pharmacy, Pune, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 1, No 3 (2009), Pagination: 220-223Abstract
Achyranthes aspera is common weed found in India and has great medicinal importance. The plant is beneficial in various ailments including stomachache, piles, boils, skin eruption and in asthma. It is also used as anti-inflammatory and as immunomodulator drug. It may act on reactive oxygen species which are one of the factor in the pathogenesis of these diseases. Various extracts of A. aspera, viz., petroleum ether extract, chloroform extract, ethyl acetate extract, ethanol extract and aqueous extract were screened for the antioxidant activity of the plant by using DPPH assay, ABTS assay and FRAP assay. Among all these extracts petroleum ether extract was found to be active as it shows lowest IC50 value in DPPH assay and highest trolox equivalent antioxidant concentration (TEAC) in ABTS assay and FRAP assay. Phytochemical screening revealed that as flavonoids, tannins and phenolic compound are absent in the plant, nonpolar compounds like steroids may be responsible for the antioxidant activity of the plant.