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Raghavendra Jayesh, S.
- Progression of Nephropathy in Age Related Diabetes
Abstract Views :473 |
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Authors
Affiliations
1 Department of Biochemistry, Sree Balaji Dental College and Hospital Bharath Institute of Higher Education and Research, (Bharath University), Narayanapuram, Pallikaranai, IN
2 Department of Biochemistry, Prince Shrivenkateshwara Arts and Science College,Venkatsennagar, IN
3 Department of Prosthodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, (Bharath University), Narayanapuram, Pallikaranai,, IN
4 Department of Prosthodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, (Bharath University), Narayanapuram, Pallikaranai, IN
5 Department of Pathology, Sree Balaji Dental College and Hospital, Narayanapuram, Pallikaranai, Chennai, IN
1 Department of Biochemistry, Sree Balaji Dental College and Hospital Bharath Institute of Higher Education and Research, (Bharath University), Narayanapuram, Pallikaranai, IN
2 Department of Biochemistry, Prince Shrivenkateshwara Arts and Science College,Venkatsennagar, IN
3 Department of Prosthodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, (Bharath University), Narayanapuram, Pallikaranai,, IN
4 Department of Prosthodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, (Bharath University), Narayanapuram, Pallikaranai, IN
5 Department of Pathology, Sree Balaji Dental College and Hospital, Narayanapuram, Pallikaranai, Chennai, IN
Source
Indian Journal of Public Health Research & Development, Vol 10, No 12 (2019), Pagination: 975-979Abstract
Diabetes and aging are associated with reduced vascular endothelial function, 20 controls and 20 subjects with type 2 diabetes age 40 participated, a series of experiments were conducted to examine the interrelationship between age, Type 2 Diabetes Mellitus and endothelial renal function. This complication is first manifested as an increase in UAE [microalbuminuria] which progresses to over albuminuria and then to renal failure In subjects with diabetes age < 40 were more prone to nephropathy which progress to End Stage Renal Disease [ESRD]Keywords
Diabetes Mellitus, Aging, Type 2 Diabetes Mellitus, ESRP, Nephropathy.- Role of Oxidative Stress in Development of Nephropathy in Diabetic Patients
Abstract Views :462 |
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Authors
Affiliations
1 Department of Biochemistry, Sree Balaji Dental College and Hospital Bharath Institute of Higher Education and Research, (Bharath University), Narayanapuram, Pallikaranai, Chennai, IN
2 Department of Biochemistry, Prince Shrivenkateshwara Arts and Science College,Venkatsennagar, Chennai, IN
3 Department of Prosthodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, (Bharath University), Narayanapuram, Pallikaranai, Chennai, IN
4 Department of Pathology, Sree Balaji Dental College and Hospital, Narayanapuram, Pallikaranai, Chennai, IN
1 Department of Biochemistry, Sree Balaji Dental College and Hospital Bharath Institute of Higher Education and Research, (Bharath University), Narayanapuram, Pallikaranai, Chennai, IN
2 Department of Biochemistry, Prince Shrivenkateshwara Arts and Science College,Venkatsennagar, Chennai, IN
3 Department of Prosthodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, (Bharath University), Narayanapuram, Pallikaranai, Chennai, IN
4 Department of Pathology, Sree Balaji Dental College and Hospital, Narayanapuram, Pallikaranai, Chennai, IN
Source
Indian Journal of Public Health Research & Development, Vol 10, No 12 (2019), Pagination: 2210-2214Abstract
Diabetes Nephropathy is a major microvascular complication of Diabetes Mellitus and the most common cause of End Stage Renal Disease (ESRD) worldwide. Hyperglycemia, a well recognized pathogentic factor of long term complications of Diabetes Mellitus, generates ROS. This attenuates antioxidative mechanisms through glycation of the scavenging enzymes. Excess amount of ROS modulate activation of protein kinaseC, mitogin activated protien kinares and various cytokines and transcription factors which eventually cause increased expression of extracellular matrix (ECM) genes with progression of fibrosis and end stage renal disease. Therefore, this study was carried out to investigate oxidant and antioxidant status in Diabetic patients for manifesting the progression to diabetic nephropathy.Keywords
Diabetic Nephropathy, Hyperglycemia, Reactive Oxygem Species, Extracellular Matrix, Oxidative Stress.- Role of Free Radicals in Cellular Signaling: A Review
Abstract Views :109 |
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Authors
Jayamathi Govindaraj
1,
Keerthidaa Govindaraj
2,
S. Raghavendra Jayesh
3,
Padmavathy Kesavaram
4,
U. Vidyarekha
5
Affiliations
1 Professor, Department of Biochemistry, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Pallikaranai, IN
2 MDS Department of Periodontics, Thai Mookambihai Dental College and Hospital, MGR University, Maduravoyal, IN
3 Professor, Department of Prosthodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, (BIHER) Pallikaranai, IN
4 Associate Professor, Department of Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Pallikaranai, IN
5 Senior Lecturer in Public Health Dentistry, Sree Balaji Dental College and Hospital, Bharath institute of Higher education and Research, Pallikaaranai, Chennai, IN
1 Professor, Department of Biochemistry, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Pallikaranai, IN
2 MDS Department of Periodontics, Thai Mookambihai Dental College and Hospital, MGR University, Maduravoyal, IN
3 Professor, Department of Prosthodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, (BIHER) Pallikaranai, IN
4 Associate Professor, Department of Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Pallikaranai, IN
5 Senior Lecturer in Public Health Dentistry, Sree Balaji Dental College and Hospital, Bharath institute of Higher education and Research, Pallikaaranai, Chennai, IN
Source
Indian Journal of Public Health Research & Development, Vol 10, No 11 (2019), Pagination: 2799-2802Abstract
Reactive oxygen species (ROS) were once considered to be deleterious agents, contributing to a vast range of pathologies. Both their damaging and beneficial effects are initiated when they target distinct molecules and consequently begin functioning as part of complex signal-transduction pathways. The recognition of ROS as signaling mediators has driven a wealth of research into their roles in both normal and pathophysiological states. The present review assesses the outline of current perspectives on redox-signaling mechanisms.Keywords
Reactive Oxygen Species, Oxidative Stress, Nitric Oxide.- A Review on Visfatin/Nicotinamide Phosphoribosyltransferase/Pre-B Cell Colony-Enhancing Factor
Abstract Views :143 |
PDF Views:0
Authors
Jayamathi Govindaraj
1,
Keerthidaa Govindaraj
2,
S. Raghavendra Jayesh
3,
Padmavathy Kesavaram
4,
U. Vidyarekha
5
Affiliations
1 Professor, Department of Biochemistry, Sree Balaji Dental College & Hospital, Bharath Institute of Higher Education and Research, Pallikaranai, IN
2 MDS Department of Periodontics, Thai Mookambihai Dental College and Hospital, MGR University, Maduravoyal, IN
3 Professor, Department of Prosthodontics, Sree Balaji Dental College & Hospital, Bharath Institute of Higher Education and Research, (BIHER), Pallikaranai, IN
4 Associate Professor, Department of Microbiology, Sree Balaji Dental College & Hospital, Bharath Institute of Higher Education and Research, Pallikaranai, IN
5 Senior Lecturer in Public Health Dentistry, Sree Balaji Dental College & Hospital, Bharath institute of Higher education and Research, Pallikaaranai, Chennai, IN
1 Professor, Department of Biochemistry, Sree Balaji Dental College & Hospital, Bharath Institute of Higher Education and Research, Pallikaranai, IN
2 MDS Department of Periodontics, Thai Mookambihai Dental College and Hospital, MGR University, Maduravoyal, IN
3 Professor, Department of Prosthodontics, Sree Balaji Dental College & Hospital, Bharath Institute of Higher Education and Research, (BIHER), Pallikaranai, IN
4 Associate Professor, Department of Microbiology, Sree Balaji Dental College & Hospital, Bharath Institute of Higher Education and Research, Pallikaranai, IN
5 Senior Lecturer in Public Health Dentistry, Sree Balaji Dental College & Hospital, Bharath institute of Higher education and Research, Pallikaaranai, Chennai, IN