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Jayakumari, S.
- A Study on Cord Blood Zinc Levels with Age and Parity in Sgapregenant Mothers
Authors
1 Professor, Department of General Medicine, Sree Balaji Medical College & Hospital, Bharath Institute of Higher Education and Research, Chennai, IN
Source
Indian Journal of Public Health Research & Development, Vol 10, No 11 (2019), Pagination: 2983-2986Abstract
Zinc deficiency is one of the most common micronutrient deficiencies in developing countries. Maternal zinc deficiency is associated with fetal growth retardation and other adverse fetal outcomes. The study aimed to determine cord blood zinc level in correlation with age and parity in the term SGA mothers. This is a prospective cross-sectional study conducted in 50 terms SGA babies and their mothers and 50 term AGA babies and their mothers. Maternal and cord blood samples were taken at delivery and zinc was estimated by endpoint nitro PAPS dye binding colorimetric method. Out of 50 study participants in parity of SGA groups, 29 were primigravida and 21 were multigravida mothers. Most of the mothers were having zinc levels ranging from 95.1 to 110 followed by 80.1 to 95. The result shows that there is no statistical significance between cord blood zinc and parity of mothers in the SGA group. Out of 50 study participants in the mode of delivery of SGA groups, 30 were NVD and 20 were LSCS mothers. Most of the mothers were having zinc levels ranging from 95.1 to 110 followed by 80.1 to 95. The zinc levels were seen more than 140 among one NVD mothers. The result shows that there is no statistical significance between cord blood zinc and mode of delivery in SGA groups. Maternal zinc level influences the cord blood zinc level. Cord blood zinc level influences the birth weight of the baby. Thus we conclude that zinc deficiency can also be one of the reasons for low birth weight babies and providing zinc supplementation to the pregnant mothers can be recommendedKeywords
Zinc, Maternal Blood, Appropriate Gestation Age, [AGE] Small Gestation Age [SGA].
- A Study on Cord Blood Zinc Levels with Age and Parity in Sgapregenant Mothers
Authors
1 Professor, Department of General Medicine, Sree Balaji Medical College & Hospital, Bharath Institute of Higher Education and Research, Chennai, IN
Source
Indian Journal of Public Health Research & Development, Vol 10, No 11 (2019), Pagination: 2983-2986Abstract
Zinc deficiency is one of the most common micronutrient deficiencies in developing countries. Maternal zinc deficiency is associated with fetal growth retardation and other adverse fetal outcomes. The study aimed to determine cord blood zinc level in correlation with age and parity in the term SGA mothers. This is a prospective cross-sectional study conducted in 50 terms SGA babies and their mothers and 50 term AGA babies and their mothers. Maternal and cord blood samples were taken at delivery and zinc was estimated by endpoint nitro PAPS dye binding colorimetric method. Out of 50 study participants in parity of SGA groups, 29 were primigravida and 21 were multigravida mothers. Most of the mothers were having zinc levels ranging from 95.1 to 110 followed by 80.1 to 95. The result shows that there is no statistical significance between cord blood zinc and parity of mothers in the SGA group. Out of 50 study participants in the mode of delivery of SGA groups, 30 were NVD and 20 were LSCS mothers. Most of the mothers were having zinc levels ranging from 95.1 to 110 followed by 80.1 to 95. The zinc levels were seen more than 140 among one NVD mothers. The result shows that there is no statistical significance between cord blood zinc and mode of delivery in SGA groups. Maternal zinc level influences the cord blood zinc level. Cord blood zinc level influences the birth weight of the baby. Thus we conclude that zinc deficiency can also be one of the reasons for low birth weight babies and providing zinc supplementation to the pregnant mothers can be recommendedKeywords
Zinc, Maternal Blood, Appropriate Gestation Age, [AGE] Small Gestation Age [SGA].- Ki-67 Proliferative Marker in Thyroid Lesions
Authors
1 Professor, Department of Anatomy, Sree Balaji Medical College and Hospital, Chrompet, Chennai, IN
Source
Indian Journal of Public Health Research & Development, Vol 10, No 11 (2019), Pagination: 3911-3916Abstract
Introduction: Approximately 5 percent of thyroid cancers happen in all thyroid nodules, regardless of their size. PTC is the most prevalent type of thyroid cancer in all thyroid cancers. Although it is hard to distinguish PTC from benign papillary hyperplasia of the thyroid gland on the basis of its morphology, it is essential to distinguish benign ones from malignant ones for early therapy and better patient management. Although the diagnostic and prognostic values of Ki-67/MIB-1 in thyroid cancer stay uncertain, it has been noted that Ki-67/MIB-1 has an impact.
Materials and Method: 60 gross samples have been taken for research. These biopsy samples were regularly fixed in 10% formalin and processed in paraffin wax. Five micron dense parts were sliced and drawn for research and hematoxylin and eosin staining of the parts was performed. Histopathological examination of these segments has been carried out. The immunohistochemistry survey using Ki-67 monoclonal antibody as a proliferation marker was conducted in 60 cases. The current survey was conducted to determine the function of ki-67 in distinct kinds of neoplastic and non-neoplastic thyroid lesions.
Results: Mean Ki67 LI values in our research were 14.12 ± 2.29, 61.42 ± 3.77 and 34.90 ± 3.49 and 18.60 ± 1.96 for PTC, FTC, FTA and NG, respectively. In this research, numerous group comparisons were made using the Bonferroni post-hoc test, and Ki-67 values were discovered to be statistically important among all thyroid lesions.
Conclusion: Although the Ki-67 marker is costly, it was discovered to be very simple to conduct and to get better outcomes. It is therefore found that the Ki-67 marker is suggested to be used in instances of dubious capsular and/or vascular invasion and follicular lesions with questionable nuclear characteristics.