Refine your search
Collections
Co-Authors
Year
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Hazarika, N K
- Candida rugosa - an Emerging Cause of Nosocomial Candidemia
Abstract Views :342 |
PDF Views:0
Authors
Affiliations
1 Department of Microbiology, Gauhati Medical College & Hospital, IN
2 Department of Microbiology, Jorhat Medical College & Hospital, Assam, IN
1 Department of Microbiology, Gauhati Medical College & Hospital, IN
2 Department of Microbiology, Jorhat Medical College & Hospital, Assam, IN
Source
Indian Journal of Public Health Research & Development, Vol 4, No 3 (2013), Pagination: 49-52Abstract
Fungemia is usually nosocomial and develops in the setting of antimicrobial therapy, cancer chemotherapy, bowel surgery or the use of intravenous plastic catheters. Here we report a case of intravenous catheter associated fungemia caused by Candida rugosa. Multiple samples of blood and catheter tip were cultured on Blood Agar, Sabouraud's Dextrose Agar media. Morphology was studied on Corn Meal Agar and HiChrome Candida Differential Agar. The isolate was further confirmed by biochemical tests and Mini API (bioMerieux, Etoile, France). The strain was also confirmed by molecular analysis in reference centre. Antifungal susceptibility test was done following M-44A Clinical and Laboratory Standard Institute (CLSI) guidelines. The isolate was labeled as Candida rugosa. The isolate was sensitive to nystatin and itraconazole. The patient expired subsequently despite antifungal therapy. Candida rugosa may represent an emerging pathogen associated with invasive medical procedures causing serious systemic infection and associated with high mortality rates.Keywords
Blood Stream Infection, Nosocomial, Candida Rugosa, Diabetes Mellitus
References
- Morse SS. Factors and determinations of disease emergence. Revue Scientifique et Technique. 2004; 2:443-446.
- Kao AS, Brandt ME, Pruitt WR et al. The epidemiology of candidemia in 2 United States cities: results of a population-based active surveillance. Clin Infect Dis 1999; 29: 1164-70.
- Ostrosky- Zeichner L, Rex J, Bennet J, Kullberg B. Deeply invasive candidiasis. Infect Dis Clin 2002; 16: 821-35.
- Milne LJR. Fungi. In: Collee JG, Fraser AG, Marmion BP, Simmons A.(eds) Mackie & Mc Cartney Practical Medical Microbiology. 14th edition. London, Churchill Livingstone, 1996:695- 717.
- Clinical and Laboratory Standards Institute. Method for antifungal disk diffusion susceptibility testing of yeasts. Approved Guideline. Document M 44-A CLSI. 2004; 24 (15), Wayne PA.
- Pfaller MA, Diekema DJ. Rare and emerging opportunistic fungal pathogens: concern for resistance beyond Candida albicans and Aspergillus fumigates. J Clin Microbiol. 2004; 42:4419-4431.
- Singh RI, Xess I, Mathur P, Behera B, Gupta B, Misra MC. Epidemiology of Candidemia in critically ill trauma patients: Experiences of a level I trauma centre in North India. J Med Microbiol. 2010; DOI: 10.1099/jmm.0.023739-0.
- Pfaller MA, Diekema DJ, Colombo AL et al. Candida rugosa, an emerging fungal pathogen with resistance to Azoles: Geographic and temporal trends from the ARTEMIS DISK antifungal surveillance program. J Clin Microbiol. 2006; 44:3578-3582.