A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Madan, Jyotsna
- Retrospective and Prospective Study of Germ Cell Tumors of the Ovary in Young and Adolescent Girls
Authors
1 Department of Pathology, Santosh Medical College, Ghaziabad.
Source
Indian Journal of Public Health Research & Development, Vol 4, No 2 (2013), Pagination: 169-172Abstract
Background and Objectives: Objective in this retrospective and prospective study was to find out the incidence of various germ cell tumors of the ovary up to 20 years of the age in the last 10 years, and to correlate clinical and pathological findings for better outcome.
Materials and Methods: Forty Two cases of ovarian germ cell tumors were studied from 2000 to 2010.Clinical data and histopathological findings were recorded.
Result: On analysis of these forty two cases, mature teratoma (57%) was the most common benign tumor and dysgerminoma (31%) was the commonest malignant tumor. Majority of the tumors were in the age group of 10-20 years.
Conclusion: Ovarian germ cell tumors are uncommon but in children and adolescent, more than 60% of ovarian neoplasms are of germ cell origin and one third are malignant. Clinical stage of the neoplasm is one of the important prognostic factors. So, early diagnosis is necessary for the better and timely management in terms of preservation of reproductive life and 5 years survival rate in cases of malignant tumors.
Keywords
Germ Cell Tumors, Ovary, Young and Adolescent Girls
References
- Talerman A.Germ cell tumours of the ovary.In: Kurman RJ,editor.Blaustein’s Pathology of the Female Genital Tract.5thed.Springer- Verleg;2002.p.967-1027.
- Young RH , Clement PB, Scully RE.Sex cordstromal, steroid cell, and germ cell tumors of the ovary.In: Mills SE,editor.Sternberg’s Diagnostic Surgical Pathology. 4thed. Philadelphia: Lippincott Williams and Wilkins; 2004. p.2595-2611.
- Scully RE.Histological typing of ovarian tumours.World Health Organization histological classification of tumors.2nded. Springer, Heidelberg;1999.
- Panteli C, Curry J, Keily E, Pierro A, Coppi P, Anderson J et al.Ovarian Germ cell tumours:a 17 year study in a single unit.Eur J Pediatr Surg 2009;19(2): 96-100.
- Gorska-Rzepka I, Blogocoska A, Zajaczek S, Zielinska D.Germinal cell tumors in young and adolescent girls.Ginekol Pol 2003;74(9):840-6.
- Bhattacharya NK, Anuradha De, Pranati B, Sristidhar M,Chakraborty S, Bandopadhyay R.Ovarian tumours in pediatric age group-A clinicopathologic study of 10 years cases in West Bengal,India.Indian J Med Paediatr Oncol 2010;31(2):54-5.
- Biswajit D, Patil CN, Sagar TG. Clinical presentation and outcome of pediatric ovarian germ cell tumors:A study of 40 patients. J Pediatr Haematol/Oncol.2010;32(2):54-57.
- Mohammed A, Malami SA, Calvin B, Abdullahi K.A histopathological study of ovarian neoplasmsin children in a tertiary hospital in northern Nigeria.Afr J Paediatr Surg2010;7:75-7.