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Edianto, Deri
- Correlation of Osteocalcin Urine Levels with Bone Mass Density in Menopause Women in H. Adam Malik General Hospital Medan
Authors
1 Department of Obstetric and Gynecology, Medical Faculty, Universitas Sumatera Utara, H. Adam Malik General Hospital Medan, ID
2 Professor of Fertility Endocrinology and Reproduction Division, Department of Obstetric and Gynecology, Medical Faculty of Universitas Sumatera Utara/President of Indonesian Menopause Society, Perkumpulan Menopause Indonesia, ID
3 Staff of Oncology and Gynecology, Department of Obstetric and Gynecology Division, Medical Faculty of Universitas Sumatera Utara, ID
4 Staff of Feto Maternal Division, Department of Obstetric and Gynecology Divison, Medical Faculty of Universitas Sumatera Utara, ID
5 Staff of Oncology and Gynecology, Department of Obstetric and Gynecology Division, Medical Faculty of Universitas Sumatera Utara, ID
Source
Indian Journal of Public Health Research & Development, Vol 11, No 1 (2020), Pagination: 1011-1016Abstract
Aim: This research is expected to revealed the correlation between urinary osteocalcin and bone density in menopausal women. Method: Descriptive study with case series design, conducted at Department of Obstetrics and Gynecology H. Adam Malik General Hospital Medan and Integrated Laboratory of Medical Faculty, University of North Sumatra and Setia Budi Hospital for DEXA Scan measurements in January 2019. The research sample was taken by 21 menopausal women using non‑probability sampling with consecutive sampling techniques. Analysis of the correlation of urinary osteocalcin with bone mass density using Pearson correlation. Results: The mean value of urinary osteocalcin in women with normal bone mass density was 6.67 ± 0,53 and the mean value for the osteopenia group was 9.05± 1.30. The results of the Pearson correlation showed a r score ‑0.803 and p <0.001. In this research shows that the higher level of urinary osteocalcin, the lower the T score. Conclusion: This research shows a significant negative correlation of urinary osteocalcin levels with bone mass density (T score) in menopausal women.Keywords
Osteocalcin, Bone Mass Density, Menopause, DEXA, Osteoporosis
- Correlation of Interleukin-6 with Serum Estradiol Mean Levels in Menopause Women at Rsup H Adam Malik Medan
Authors
1 Department of Obstetric and Gynecology, Medicine Faculty, Universitas Sumatera Utara, ID
2 Professor of Fertility Endocrine Reproduction, Department of Obstetrics and Gynecology, Medical Faculty of Universitas Sumatera Utara/President of Indonesian Menopause Association (Perkumpulan Menopause Indonesia), ID
3 Staff of Social Obstetric Division, Department of Obstetrics and Gynecology, Medical Faculty of Universitas Sumatera Utara, ID
4 Professor of Feto Maternal Division, Department of Obstetrics and Gynecology, Medical Faculty of Universitas Sumatera Utara, ID
5 Staff of Oncology Gynecology Division, Department of Obstetrics and Gynecology, Medical Faculty of Universitas Sumatera Utara, ID
Source
Indian Journal of Public Health Research & Development, Vol 11, No 1 (2020), Pagination: 1337-1342Abstract
Aim: To determine the correlation of Interleukin-6 (IL-6) with serum estradiol levels in menopausal women.
Method: This research is a case series research in postmenopausal women to assess the correlation between Interleukin-6 (IL-6) and serum estradiol levels that performed at H Adam Malik General Hospital Medan, starting in August 2017 until 38 samples which met the inclusion and exclusion criteria were fulfill,using non probability sampling technique with consecutive sampling. Serum estradiol and IL-6 levels was examined, then sent to the clinical laboratory. Data tabulated to be analyzed statistically.
Results: The mean serum estradiol level in menopausal women is 29.74 ± 18.69. The mean IL-6 level was 85.03 ± 33.66, in this research showed that in menopausal women there was an increase in IL-6 levels. By using the Spearman Test, the results showed that there was a significant correlation between estradiol and IL-6 with p value <0.004.
Conclusion: There is a significant negative correlation between serum estradiol and IL-6 levels, which means that there is an inverse relationship between serum estradiol and IL-6 levels with weak negative strength, where decreasing estradiol does not always increase IL-6 levels.